The Ubiquitin Ligase TRAF6 Negatively Regulates the JAK-STAT Signaling Pathway by Binding to STAT3 and Mediating Its Ubiquitination

PLoS ONE

Volumn 7, Issue 11, 2012, Pages

  Wei, Juncheng ^a,b   Yuan, Yanzhi ^a   Jin, Chaozhi ^a   Chen, Hui ^a   Leng, Ling ^a   He, Fuchu ^a,b,c   Wang, Jian ^a  

^a BEIJING INSTITUTE OF RADIATION MEDICINE   (China)

^b INSTITUTE OF BASIC MEDICAL SCIENCES   (China)

^c FUDAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 1 ANTICHYMOTRYPSIN; ALPHA INTERFERON; C REACTIVE PROTEIN; JANUS KINASE 2; STAT3 PROTEIN; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6;

ACT GENE; ARTICLE; CONTROLLED STUDY; CRP GENE; DOWN REGULATION; GENE; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; PROTEIN PROTEIN INTERACTION; RING FINGER MOTIF; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; UBIQUITINATION; ZINC FINGER MOTIF;

CYTOKINES; DOWN-REGULATION; GENE EXPRESSION REGULATION; HEK293 CELLS; HUMANS; INFLAMMATION; JANUS KINASES; LUCIFERASES; NF-KAPPA B; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; TNF RECEPTOR-ASSOCIATED FACTOR 6; TRANSCRIPTION, GENETIC; UBIQUITIN; UBIQUITIN-PROTEIN LIGASES;

EID: 84869767938     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0049567     Document Type: Article

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