Fe2+ block and permeation of CaV3.1 (α1G) T-type calcium channels: Candidate mechanism for non-transferrin-mediated Fe2+ influx

Molecular Pharmacology

Volumn 82, Issue 6, 2012, Pages 1194-1204

  Lopin, Kyle V ^a   Gray, I Patrick ^a   Obejero Paz, Carlos A ^a,c   Thévenod, Frank ^b   Jones, Stephen W ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF WITTEN HERDECKE   (Germany)

^c ChanTest Corporation   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 ( 2 ( N [( 3 BENZIMIDAZOL 2 YL)PROPYL] N METHYLAMINO)ETHYL) 6 FLUORO 1,2,3,4 TETRAHYDRO 1 ISOPROPYL 2 NAPHTHYL CYCLOPROPANECARBOXYLIC ACID; ASCORBIC ACID; CALCIUM CHANNEL; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM CHANNEL CAV3.1; CALCIUM CHANNEL T TYPE; CALCIUM ION; FERROUS ION; IRON; IRON BINDING PROTEIN; MAGNESIUM ION; NNC 550396; NON TRANSFERRIN BOUND IRON; TRANSFERRIN; UNCLASSIFIED DRUG;

ARTICLE; CELL LINE; CELL MEMBRANE DEPOLARIZATION; CELL MEMBRANE PERMEABILITY; CHANNEL GATING; CONTROLLED STUDY; ELECTRIC POTENTIAL; EXTRACELLULAR SPACE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IRON TRANSPORT; PH; PRIORITY JOURNAL; PROBABILITY; RELATIVE DENSITY; SURFACE CHARGE; WHOLE CELL;

BARIUM; CALCIUM; CALCIUM CHANNELS, T-TYPE; CELL LINE; FERROUS COMPOUNDS; HEK293 CELLS; HUMANS; ION CHANNEL GATING; MAGNESIUM; MEMBRANE POTENTIALS; PATCH-CLAMP TECHNIQUES; TRANSFERRIN;

EID: 84869751720     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.112.080184     Document Type: Article

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