Evaluation of a two-site, three-barrier model for permeation in Ca V3.1 (α1G) T-type calcium channels: Ca2+, Ba 2+, Mg2+, and Na+

Journal of Membrane Biology

Volumn 235, Issue 2, 2010, Pages 131-143

  Lopin, Kyle V ^a   Obejero Paz, Carlos A ^a   Jones, Stephen W ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Channel block; Chord conductance; Eyring model; Ion selectivity; Patch clamp; Rate theory; Reversal potential

Indexed keywords

BARIUM ION; CALCIUM CHANNEL T TYPE; CALCIUM ION; MAGNESIUM ION; NICKEL; SODIUM ION;

ARTICLE; CELL STRAIN HEK293; CONCENTRATION (PARAMETERS); CYTOPLASM; DEPOLARIZATION; ELECTRIC POTENTIAL; EXPERIMENT; HUMAN; HUMAN CELL; WHOLE CELL;

BARIUM; CALCIUM; CALCIUM CHANNELS, T-TYPE; CELL LINE; HUMANS; MAGNESIUM; MODELS, BIOLOGICAL; SODIUM;

EID: 77954424228     PISSN: 00222631     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00232-010-9264-3     Document Type: Article

References (29)

1. W Almers EW McCleskey 1984 Non-selective conductance in calcium channels of frog muscle: calcium selectivity in a single-file pore J Physiol 353 585 608 1:STN:280:DyaL2M%2FgvFehsg%3D%3D 6090646 (Pubitemid 14061541)
2. W Almers EW McCleskey PT Palade 1984 A non-selective cation conductance in frog muscle membrane blocked by micromolar external calcium ions J Physiol 353 565 583 1:STN:280:DyaL2M%2FgvFeiuw%3D%3D 6090645
3. OS Andersen 1999 Graphic representation of the results of kinetic analyses [editorial] J Gen Physiol 114 589 590 10.1085/jgp.114.4.589 1:STN:280:DC%2BD3c%2FjsFKksg%3D%3D 10577023 (Pubitemid 29473426)
4. S Bergling 1999 Which model is best? Let the data decide J Gen Physiol 114 591 10.1085/jgp.114.4.591 1:STN:280:DC%2BD3c%2FjsFKksw%3D%3D 10577024 (Pubitemid 29473427)
5. V3.1 Biophys J 95 931 941 10.1529/biophysj.107.128124 1:CAS:528:DC%2BD1cXotlKhsbg%3D 18375519
6. D Boda M Valisko B Eisenberg W Nonner D Henderson D Gillespie 2006 The effect of protein dielectric coefficient on the ionic selectivity of a calcium channel J Chem Phys 125 34901 10.1063/1.2212423 16863379 (Pubitemid 44107163)
7. D Boda M Valisko D Henderson B Eisenberg D Gillespie W Nonner 2009 Ionic selectivity in L-type calcium channels by electrostatics and hard-core repulsion J Gen Physiol 133 497 509 10.1085/jgp.200910211 1:CAS:528:DC%2BD1MXmtVOjsLY%3D 19398776
8. CC Chow JA White 1996 Spontaneous action potentials due to channel fluctuations Biophys J 71 3013 3021 10.1016/S0006-3495(96)79494-8 1:CAS:528:DyaK28XnsFKlt7c%3D 8968572
9. TX Dang EW McCleskey 1998 Ion channel selectivity through stepwise changes in binding affinity J Gen Physiol 111 185 193 10.1085/jgp.111.2.185 1:CAS:528:DyaK1cXhtFWlt7s%3D 9450938
10. DT Gillespie 1977 Exact stochastic simulation of coupled chemical reactions J Phys Chem 81 2340 2361 10.1021/j100540a008 1:CAS:528: DyaE1cXht1GntA%3D%3D
11. P Hess RW Tsien 1984 Mechanism of ion permeation through calcium channels Nature 309 453 456 10.1038/309453a0 1:CAS:528:DyaL2cXksFShsLY%3D 6328315
12. AL Hodgkin AF Huxley 1952 The components of membrane conductance in the giant axon of Loligo J Physiol 116 473 496 1:STN:280:DyaG38%2Fns1yhtg%3D%3D 14946714
13. + J Gen Physiol 132 223 238 10.1085/jgp.200809986 1:CAS:528:DC%2BD1cXhtVeksbnP 18663131
14. 2+ channels: estimates of the size and surface potential at the pore mouths Neuron 9 515 526 10.1016/0896-6273(92)90189-K 1:CAS:528: DyaK38XmsVOhsbg%3D 1381926
15. DG Levitt 1986 Interpretation of biological ion channel flux data-reaction-rate versus continuum theory Annu Rev Biophys Biophys Chem 15 29 57 10.1146/annurev.bb.15.060186.000333 1:CAS:528:DyaL28XkvFaqt7o%3D 2424476
16. 2+ J Physiol 430 159 188 1:STN:280:DyaK3M3gt1erug%3D%3D 1964965
17. EW McCleskey 1999 Calcium channel permeation: a field in flux J Gen Physiol 113 765 772 10.1085/jgp.113.6.765 1:CAS:528:DyaK1MXktVSrs70%3D 10352027 (Pubitemid 29270405)
18. EW McCleskey W Almers 1985 The Ca channel in skeletal muscle is a large pore Proc Natl Acad Sci USA 82 7149 7153 10.1073/pnas.82.20.7149 1:STN:280:DyaL28%2Fhs1ymsA%3D%3D 2413461 (Pubitemid 16209710)
19. W Nonner B Eisenberg 1998 Ion permeation and glutamate residues linked by Poisson-Nernst-Planck theory in L-type calcium channels Biophys J 75 1287 1305 10.1016/S0006-3495(98)74048-2 1:CAS:528:DyaK1cXlvVCrurk%3D 9726931
20. W Nonner DP Chen B Eisenberg 1999 Progress and prospects in permeation J Gen Physiol 113 773 782 10.1085/jgp.113.6.773 1:CAS:528:DyaK1MXktVSrs7o%3D 10352028 (Pubitemid 29270406)
21. W Nonner L Catacuzzeno B Eisenberg 2000 Binding and selectivity in L-type calcium channels: a mean spherical approximation Biophys J 79 1976 1992 10.1016/S0006-3495(00)76446-0 1:CAS:528:DC%2BD3cXnt12ht70%3D 11023902
22. 2+ channel J Gen Physiol 124 631 640 10.1085/jgp.200409167 1:CAS:528:DC%2BD2MXjt1Onsg%3D%3D 15572343 (Pubitemid 39628131)
23. V3.1 (α1G) T-type calcium channels J Gen Physiol 132 239 250 10.1085/jgp.200809988 1:CAS:528:DC%2BD1cXhtVeksbnJ 18663132
24. E Perez-Reyes LL Cribbs A Daud AE Lacerda J Barclay MP Williamson M Fox M Rees JH Lee 1998 Molecular characterization of a neuronal low-voltage-activated T-type calcium channel Nature 391 896 900 10.1038/36110 1:CAS:528: DyaK1cXhsFylu7g%3D 9495342 (Pubitemid 28157667)
25. 2+ selectivity of α1G T-type calcium channels Biophys J 79 3052 3062 10.1016/S0006-3495(00)76540-4 1:CAS:528:DC%2BD3MXitFeg 11106611
26. AM Woodhull 1973 Ionic blockage of sodium channels in nerve J Gen Physiol 61 687 708 10.1085/jgp.61.6.687 1:CAS:528:DyaE3sXktlSjsro%3D 4541078
27. + on the Ca channel outward current in mouse neoplastic B lymphocytes J Gen Physiol 96 559 579 10.1085/jgp.96.3.559 1:STN:280:DyaK3M%2Fjsl2hsg%3D%3D 2172442 (Pubitemid 20301276)
28. 2+ channels Nature 366 158 161 10.1038/366158a0 1:CAS:528:DyaK2cXivVShtw%3D%3D 8232554 (Pubitemid 23351820)
29. 2+ J Gen Physiol 95 911 939 10.1085/jgp.95.5.911 1:CAS:528:DyaK3cXktlyjsbk%3D 2163433 (Pubitemid 20171078)