ATP and glutamate released via astroglial connexin 43 hemichannels mediate neuronal death through activation of pannexin 1 hemichannels

Journal of Neurochemistry

Volumn 118, Issue 5, 2011, Pages 826-840

  Orellana, Juan A ^a   Froger, Nicolas ^b   Ezan, Pascal ^b   Jiang, Jean X ^c   Bennett, Michael V L ^d   Naus, Christian C ^e   Giaume, Christian ^b   Sáez, Juan C ^a,d,f  

^a PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE   (Chile)

^b l'alimentation et l'Environnement   (France)

^c UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^d ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^e UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^f Centro Interdisciplinario de Neurociencias de Valparaíso   (Chile)

Author keywords

Alzheimer's disease; amyloid peptide; connexin; cytokines; diabetes mellitus; gap junctions; pannexin; stroke

Indexed keywords

ADENOSINE TRIPHOSPHATE; AMYLOID BETA PROTEIN; CONNEXIN 43; GLUTAMIC ACID; MEMBRANE PROTEIN; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; PROBENECID; PROTEIN PANNEXIN 1; PURINERGIC P2X RECEPTOR; PURINERGIC P2X RECEPTOR ANTAGONIST; SURAMIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; ASTROCYTE; CELL PERMEABILIZATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME RELEASE; FEMALE; HYPOXIA; MICROGLIA; MOUSE; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REOXYGENATION;

ADENOSINE TRIPHOSPHATE; AMYLOID BETA-PEPTIDES; ANIMALS; ANIMALS, NEWBORN; ASTROCYTES; BIOTINYLATION; CELL DEATH; CELL HYPOXIA; CELLS, CULTURED; CEREBRAL CORTEX; COCULTURE TECHNIQUES; CONNEXIN 43; CONNEXINS; CULTURE MEDIA, CONDITIONED; FEMALE; FLUORESCEINS; GLUTAMIC ACID; INTERLEUKIN-1BETA; LANTHANUM; MICE; MICE, KNOCKOUT; MICROTUBULE-ASSOCIATED PROTEINS; NERVE TISSUE PROTEINS; NEURONS; NEUROPEPTIDES; OXYGEN; PEPTIDE FRAGMENTS; TIME FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 80051759671     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2011.07210.x     Document Type: Article

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