Quinine, a blocker of neuronal Cx36 channels, suppresses seizure activity in rat neocortex in vivo

Epilepsia

Volumn 46, Issue 10, 2005, Pages 1581-1591

  Gajda, Zita ^a   Szupera, Zoltán ^a   Blazsó, Gábor ^a   Szente, Magdolna ^a  

^a UNIVERSITY OF SZEGED   (Hungary)

Author keywords

4 AP induced seizure; Carbenoxolone; Cx36; Epileptogenesis; Gap junctions; Ictogenesis; In vivo; Quinine

Indexed keywords

4 AMINOPYRIDINE; CARBENOXOLONE; CONNEXIN 36; OCTANOL; QUININE; GAP JUNCTION PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICONVULSANT ACTIVITY; ARTICLE; ASTROCYTE; CONTROLLED STUDY; CORTICAL SYNCHRONIZATION; DISEASE DURATION; DRUG SELECTIVITY; EPILEPTIC DISCHARGE; EPILEPTIC FOCUS; EPILEPTOGENESIS; GAP JUNCTION; GLIA; IN VIVO STUDY; LATENT PERIOD; NEOCORTEX; NONHUMAN; PRIORITY JOURNAL; QUALITATIVE ANALYSIS; RAT; SEIZURE; TREATMENT OUTCOME; ANIMAL; BRAIN CORTEX; CELL JUNCTION; CHEMICALLY INDUCED DISORDER; DOSE RESPONSE; DRUG EFFECT; ELECTROENCEPHALOGRAPHY; FEMALE; MALE; NERVE CELL; NERVE TRACT; PATHOPHYSIOLOGY; STATISTICS; WISTAR RAT;

4-AMINOPYRIDINE; ANIMALS; ASTROCYTES; CARBENOXOLONE; CEREBRAL CORTEX; CONNEXINS; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROENCEPHALOGRAPHY; FEMALE; GAP JUNCTIONS; MALE; NEOCORTEX; NEURAL PATHWAYS; NEURONS; OCTANOLS; QUININE; RATS; RATS, WISTAR; SEIZURES;

EID: 27244443051     PISSN: 00139580     EISSN: 15281167     Source Type: Journal    
DOI: 10.1111/j.1528-1167.2005.00254.x     Document Type: Article

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