Dose-dependent protective effect of connexin43 mimetic peptide against neurodegeneration in an ex vivo model of epileptiform lesion

Epilepsy Research

Volumn 92, Issue 2-3, 2010, Pages 153-162

  Yoon, Jinny J ^a   Green, Colin R ^a   O'Carroll, Simon J ^a   Nicholson, Louise F B ^a  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

Connexin; Epilepsy; Hippocampal slice culture; Mimetic peptide; Propidium iodide

Indexed keywords

BICUCULLINE METHOCHLORIDE; CONNEXIN 43; PEPTIDOMIMETIC AGENT; PROPIDIUM IODIDE; UNCLASSIFIED DRUG; VALYLASPARTYLCYSTEINYLPHENYLALANYLLEUCYLSERYLARGINYLPROLYLTHREONYLGLUTAMYLLYSYLTHREONINE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN DAMAGE; BRAIN REGION; BRAIN SLICE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG TARGETING; EPILEPSY; EX VIVO STUDY; GAP JUNCTION; HIPPOCAMPUS; NERVE DEGENERATION; NERVE INJURY; NEUROPATHOLOGY; NEUROPROTECTION; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT; TISSUE SURVIVAL;

ANIMALS; ANIMALS, NEWBORN; BICUCULLINE; CA1 REGION, HIPPOCAMPAL; CELL DEATH; CONNEXIN 43; CULTURE MEDIA, SERUM-FREE; DOSE-RESPONSE RELATIONSHIP, DRUG; GABA ANTAGONISTS; MICROTUBULE-ASSOCIATED PROTEINS; NERVE DEGENERATION; PEPTIDES; RATS; RATS, WISTAR; TIME FACTORS;

EID: 78650176658     PISSN: 09201211     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.eplepsyres.2010.08.014     Document Type: Article

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