메뉴 건너뛰기




Volumn 12, Issue 12, 2012, Pages 1601-1610

An update on vaccines for tuberculosis - there is more to it than just waning of BCG efficacy with time

Author keywords

Clinical trials; Cytolytic t cells; Dna vaccine; Latency; Prime boost protocols; Tuberculosis; Vaccine

Indexed keywords

ADAG 85A; AERAS 402; AERAS 422; BCG VACCINE; DNA VACCINE; GAMMA INTERFERON; GSK 692342; HYBRID 1; ID 93; IKEPLUS; INTERLEUKIN 17; INTERLEUKIN 2; LIVE VACCINE; MVA AG 85A; RUTI VACCINE; SUBUNIT VACCINE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VPM 1002;

EID: 84869429756     PISSN: 14712598     EISSN: None     Source Type: Journal    
DOI: 10.1517/14712598.2012.721768     Document Type: Review
Times cited : (27)

References (62)
  • 1
    • 53049085393 scopus 로고    scopus 로고
    • Origin, spread and demography of the mycobacterium tuberculosis complex
    • Wirth T, Hildebrand F, Allix- Buegec C. Origin, spread and demography of the mycobacterium tuberculosis complex. PLoS Pathog 2008;4:e1000160
    • (2008) PLoS Pathog , vol.4
    • Wirth, T.1    Hildebrand, F.2    Allix- Buegec, C.3
  • 2
    • 0003635217 scopus 로고    scopus 로고
    • WHO 2011. Available From: who Inttbpublicationsglobal report 2011
    • WHO 2011. Global tuberculosis control 2011. Available from: who int/tb/publications/global report 2011
    • Global Tuberculosis Control 2011
  • 4
    • 43949107191 scopus 로고    scopus 로고
    • Thinking in three dimensions: A web-based algorithm to aid the interpretation of tuberculin skin test results
    • Menzies D, Gardiner G, Farhat M, et al. Thinking in three dimensions: A web-based algorithm to aid the interpretation of tuberculin skin test results. Intl J Tuberc Lung Dis 2008;12:498-505
    • (2008) Intl J Tuberc Lung Dis , vol.12 , pp. 498-505
    • Menzies, D.1    Gardiner, G.2    Farhat, M.3
  • 5
    • 0012746992 scopus 로고    scopus 로고
    • The growing burden of tuberculosis: Global trends and interactions with the HIV epidemic
    • Corbett EL, Watt CJ, Walker N, et al. The growing burden of tuberculosis: Global trends and interactions with the HIV epidemic. Arch Intern Med 2003;163:1009-21
    • (2003) Arch Intern Med , vol.163 , pp. 1009-1021
    • Corbett, E.L.1    Watt, C.J.2    Walker, N.3
  • 7
    • 84869410925 scopus 로고    scopus 로고
    • Takii T, Maeyama J, Yamamoto S, editors. BCG -vaccine and adjuvant. Japan Anti-Tuberculosis Association Tokyo
    • Jackson M, Yamamoto S. Historical background of Mycobacterium bovis BCG. In: TAKII T, Maeyama J, Yamamoto S, editors. BCG -vaccine and adjuvant. Japan Anti-Tuberculosis Association; Tokyo: 2011. p. 3-12
    • (2011) Historical Background Of Mycobacterium Bovis BCG , pp. 3-12
    • Jackson, M.1    Yamamoto, S.2
  • 8
    • 0028153628 scopus 로고    scopus 로고
    • Recombinant live vaccine candidates against tuberculosis
    • Epub ahead of print 9. Colditz GA, Brewer TF, Berkey CS, et al. Efficacy of BCG vaccine in the prevention of tuberculosis: Meta-analysis of the published literature. JAMA 1994
    • Kaufmann S, Gengerbacher M. Recombinant live vaccine candidates against tuberculosis. Curr Opin Biotechnol 2012;Epub ahead of print 9. Colditz GA, Brewer TF, Berkey CS, et al. Efficacy of BCG vaccine in the prevention of tuberculosis: Meta-analysis of the published literature. JAMA 1994;271:689-702
    • (2012) Curr Opin Biotechnol , vol.271 , pp. 689-702
    • Kaufmann, S.1    Gengerbacher, M.2
  • 9
    • 0028872014 scopus 로고
    • Variation in protection by BCG: Implications of and for heterologous immunity
    • Fine PEM. Variation in protection by BCG: Implications of and for heterologous immunity. Lancet 1995;346:1339-45
    • (1995) Lancet , vol.346 , pp. 1339-1345
    • Fine, P.E.M.1
  • 10
    • 0029068308 scopus 로고
    • The efficacy of bacillus Calmette-Guerin vaccination of newborns and infants in the prevention of tuberculosis: Meta-analyses of the published literature
    • Colditz G, Berkey C, Mosteller F. The efficacy of bacillus Calmette-Guerin vaccination of newborns and infants in the prevention of tuberculosis: Meta-analyses of the published literature. Pediatrics 1995;96:29-35
    • (1995) Pediatrics , vol.96 , pp. 29-35
    • Colditz, G.1    Berkey, C.2    Mosteller, F.3
  • 11
    • 84856843927 scopus 로고    scopus 로고
    • Tuberculosis pathogenesis and immunity
    • Philips JA, Ernst JD. Tuberculosis pathogenesis and immunity. Ann Rev Pathol 2012;7:353-84
    • (2012) Ann Rev Pathol , Issue.7 , pp. 353-384
    • Philips, J.A.1    Ernst, J.D.2
  • 12
    • 0043163431 scopus 로고    scopus 로고
    • HIV and tuberculosis: Surveillance revisited
    • Corbett EL. HIV and tuberculosis: Surveillance revisited. Intl J Tuberc Lung Dis 2003;7:709
    • (2003) Intl J Tuberc Lung Dis , vol.7 , pp. 709
    • Corbett, E.L.1
  • 13
    • 0347089095 scopus 로고    scopus 로고
    • The human model: A genetic dissection of immunity to infection in natural conditions
    • Casanova JL, Abel L. The human model: A genetic dissection of immunity to infection in natural conditions. Nature Rev Immunol 2004;4:55-66
    • (2004) Nature Rev Immunol , vol.4 , pp. 55-66
    • Casanova, J.L.1    Abel, L.2
  • 14
    • 77953274576 scopus 로고    scopus 로고
    • How tumour necrosis factor blockers interfere with tuberculosis immunity
    • Harris J, Keane J. How tumour necrosis factor blockers interfere with tuberculosis immunity. Clin Exp Immunol 2010; 161:1-9
    • (2010) Clin Exp Immunol , Issue.161 , pp. 1-9
    • Harris, J.1    Keane, J.2
  • 15
    • 65849488547 scopus 로고    scopus 로고
    • Analysis of mycobacterium tuberculosis -specific CD8+ T cells in patients with active tuberculosis and in individuals with latent infection
    • Caccamo N, Guggino G, Meraviglia S, et al. Analysis of mycobacterium tuberculosis -specific CD8+ T cells in patients with active tuberculosis and in individuals with latent infection. PLoS One 2009;4:e5528
    • (2009) PLoS One , vol.4
    • Caccamo, N.1    Guggino, G.2    Meraviglia, S.3
  • 16
    • 66449083072 scopus 로고    scopus 로고
    • Anti-TNF immunotherapy reduces CD8+ T cell-mediated antimicrobial activity against Mycobacterium tuberculosis in humans
    • Bruns H, Meinken C, Schauenberg P, et al. Anti-TNF immunotherapy reduces CD8+ T cell-mediated antimicrobial activity against Mycobacterium tuberculosis in humans. J Clin Invest 2009;119:1167-77
    • (2009) J Clin Invest , vol.119 , pp. 1167-1177
    • Bruns, H.1    Meinken, C.2    Schauenberg, P.3
  • 17
    • 77958475885 scopus 로고    scopus 로고
    • Specific T cell frequency and cytokine expression profile do not correlate with protection against tuberculosis after bacillus Calmette-Guerin vaccination of newborns
    • Kagina BM, Abel B, Scriba TJ, Hughes E. Specific T cell frequency and cytokine expression profile do not correlate with protection against tuberculosis after bacillus Calmette-Guerin vaccination of newborns. Am J Respir Crit Care Med 2010;182:1073-9
    • (2010) Am J Respir Crit Care Med , Issue.182 , pp. 1073-1079
    • Kagina, B.M.1    Abel, B.2    Scriba, T.J.3    Hughes, E.4
  • 19
    • 77955894773 scopus 로고    scopus 로고
    • An interferon-inducible neutrophildriven blood transcriptional signature in human tuberculosis
    • Berry MP, Graham CM, McNab FW, et al. An interferon-inducible neutrophildriven blood transcriptional signature in human tuberculosis. Nature 2010;466:973-7
    • (2010) Nature , Issue.466 , pp. 973-977
    • Berry, M.P.1    Graham, C.M.2    McNab, F.W.3
  • 20
    • 80055042377 scopus 로고    scopus 로고
    • Functional correlations of pathogenesisdriven gene expression signatures in tuberculosis
    • Maertzdorf J, Ota M, Repsilber D, et al. Functional correlations of pathogenesisdriven gene expression signatures in tuberculosis. PLoS One 2011;6:e26938
    • (2011) PLoS One , Issue.6
    • Maertzdorf, J.1    Ota, M.2    Repsilber, D.3
  • 21
    • 80053577116 scopus 로고    scopus 로고
    • Immunodiagnosis of tuberculosis: A dynamic view of biomarker discovery
    • Kunnath-Velayudhan S, Gennaro ML. Immunodiagnosis of tuberculosis: A dynamic view of biomarker discovery. Clin Microbiol Rev 2011;24:792-805
    • (2011) Clin Microbiol Rev , Issue.24 , pp. 792-805
    • Kunnath-Velayudhan, S.1    Gennaro, M.L.2
  • 22
    • 79952732234 scopus 로고    scopus 로고
    • Human lung immunity against Mycobacterium tuberculosis: Insights into pathogenesis and protection
    • Schwander S, Dheda K. Human lung immunity against Mycobacterium tuberculosis: Insights into pathogenesis and protection. Am J Respir Crit Care Med 2011;183:696-707
    • (2011) Am J Respir Crit Care Med , Issue.183 , pp. 696-707
    • Schwander, S.1    Dheda, K.2
  • 23
    • 84858711974 scopus 로고    scopus 로고
    • Tuberculosis vaccines: A strategic blueprint for the next decade
    • BrennanMJ, Thole J. Tuberculosis vaccines: A strategic blueprint for the next decade. Tuberculosis (Edinb) 2012;92:S6-S13
    • (2012) Tuberculosis (Edinb , Issue.92
    • Brennan, M.J.1    Thole, J.2
  • 24
    • 84870805025 scopus 로고    scopus 로고
    • Stop TB Partnership Working Group on New TB Vaccines. StopTB partnership 2011
    • Stop TB Partnership Working Group on New TB Vaccines. Tuberculosis Vaccine Pipeline-2011. StopTB partnership 2011
    • Tuberculosis Vaccine Pipeline-2011
  • 25
    • 84863690353 scopus 로고    scopus 로고
    • Vaccines against tuberculosis: Where are we and where do we need to go ?
    • Ottenhoff THM, Kaufmann SHE. Vaccines against tuberculosis: Where are we and where do we need to go ? PLoS Pathog 2012;8:e1002607
    • (2012) PLoS Pathog , Issue.8
    • Ottenhoff, T.H.M.1    Kaufmann, S.H.E.2
  • 26
    • 55649113699 scopus 로고    scopus 로고
    • PhoP: A missing piece in the intricate puzzle of mycobacterium tuberculosis Virulence
    • Gonzalo-Asensio J, Mostowy S, Harders-Westerveen J, et al. PhoP: A missing piece in the intricate puzzle of mycobacterium tuberculosis Virulence. PLoS one 2008;3:e3496
    • (2008) PLoS one , vol.3
    • Gonzalo-Asensio, J.1    Mostowy, S.2    Harders-Westerveen, J.3
  • 28
    • 84869412737 scopus 로고    scopus 로고
    • Takii T, Maeyama J-I, Yamamoto S, editors. BCG- vaccine and aduvant. Japan Anti-Tuberculosis Association Tokyo
    • Mori T. Efficacy of BCG vaccination. In: TAKII T, Maeyama J-I, Yamamoto S, editors. BCG- vaccine and aduvant. Japan Anti-Tuberculosis Association; Tokyo: 2011. p. 13-45
    • (2011) Efficacy Of BCG Vaccination , pp. 13-45
    • Mori, T.1
  • 29
    • 2342584774 scopus 로고    scopus 로고
    • Long-term efficacy of BCG vaccine in American Indians and Alaska Natives: A 60 year follow-up study
    • Aronson NE, Santosham M, Comstock GW, et al. Long-term efficacy of BCG vaccine in American Indians and Alaska Natives: A 60 year follow-up study. JAMA 2004;291:2086-91
    • (2004) JAMA , vol.291 , pp. 2086-2091
    • Aronson, N.E.1    Santosham, M.2    Comstock, G.W.3
  • 30
    • 2342485039 scopus 로고    scopus 로고
    • A booster for tuberculosis vaccines
    • Dye C. A booster for tuberculosis vaccines. JAMA 2004;291:2127-8
    • (2004) JAMA , vol.291 , pp. 2127-2128
    • Dye, C.1
  • 31
    • 22944433876 scopus 로고    scopus 로고
    • The success and failure of BCG-implications for a novel tuberculosis vaccine
    • Andersen P, Doherty M. The success and failure of BCG-implications for a novel tuberculosis vaccine. Nat Rev Microbiol 2005;3:656-65
    • (2005) Nat Rev Microbiol , vol.3 , pp. 656-665
    • Andersen, P.1    Doherty, M.2
  • 32
    • 33645224419 scopus 로고    scopus 로고
    • Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response
    • Liu PT, Stenger S, Li H, et al. Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response. Science 2006;311:1770-3
    • (2006) Science , vol.311 , pp. 1770-1773
    • Liu, P.T.1    Stenger, S.2    Li, H.3
  • 33
    • 80053351516 scopus 로고    scopus 로고
    • Tuberculosis vaccines: Progress and chalenges
    • Checkley AM, McShane H. Tuberculosis vaccines: Progress and chalenges. Trends Pharm Sci 2011;32:601-6
    • (2011) Trends Pharm Sci , Issue.32 , pp. 601-606
    • Checkley, A.M.1    McShane, H.2
  • 34
    • 84863393669 scopus 로고    scopus 로고
    • A human challenge model for mycobacterium tuberculosis using mycobacterium bovis bacille calmette-guerin
    • Minassian AM, Satti I, Poulton ID, et al. A human challenge model for mycobacterium tuberculosis using mycobacterium bovis bacille calmette-guerin. J Infect Dis 2012;205:1035-42
    • (2012) J Infect Dis , Issue.205 , pp. 1035-1042
    • Minassian, A.M.1    Satti, I.2    Poulton, I.D.3
  • 35
    • 7244236723 scopus 로고    scopus 로고
    • Novel human in vitro system for evaluating antimycobacterial vaccines
    • Kampmann B, Tena GN, Mzazi S, et al. Novel human in vitro system for evaluating antimycobacterial vaccines. Infect Immun 2004;72:6401-7
    • (2004) Infect Immun , vol.72 , pp. 6401-6407
    • Kampmann, B.1    Tena, G.N.2    Mzazi, S.3
  • 36
    • 70449570269 scopus 로고    scopus 로고
    • An immunologic model for rapid vaccine assessment - A clinical trial in a test tube
    • Higbee RG, Byers AM, Dhir V. An immunologic model for rapid vaccine assessment - a clinical trial in a test tube. Altern Lab Anim 2009;37:19-27
    • (2009) Altern Lab Anim , vol.37 , pp. 19-27
    • Higbee, R.G.1    Byers, A.M.2    Dhir, V.3
  • 37
    • 80053963965 scopus 로고    scopus 로고
    • A recombinant mycobacterium smegmatis induces potent bactericidal immunity against Mycobacterium tuberculosis
    • Sweeney KA, Dao DN, Goldberg MF, et al. A recombinant mycobacterium smegmatis induces potent bactericidal immunity against Mycobacterium tuberculosis. Nat Med 2011;17:1261-8
    • (2011) Nat Med , Issue.17 , pp. 1261-1268
    • Sweeney, K.A.1    Dao, D.N.2    Goldberg, M.F.3
  • 38
    • 84863815961 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis lacking all mycolic acid cyclopropanation is viable but highly attenuated and hyperinflammatory in mice
    • Barkan D, Hedhli D, Yan H-G, et al. Mycobacterium tuberculosis lacking all mycolic acid cyclopropanation is viable but highly attenuated and hyperinflammatory in mice. Infect Immun 2012;80:1958-68
    • (2012) Infect Immun , vol.80 , pp. 1958-68
    • Barkan, D.1    Hedhli, D.2    Yan, H.-G.3
  • 39
    • 46449096343 scopus 로고    scopus 로고
    • Mycolic acid modification by the mmaA4 gene of M. tuberculosis modulates IL-12 production
    • Dao DN, Sweeney K, Hsu T, et al. Mycolic acid modification by the mmaA4 gene of M. tuberculosis modulates IL-12 production. PLoS Pathog 2008;4:e1000081
    • (2008) PLoS Pathog , vol.4
    • Dao, D.N.1    Sweeney, K.2    Hsu, T.3
  • 40
    • 78851469937 scopus 로고    scopus 로고
    • Molecular structure of the Mycobacterium tuberculosis virulence factor, mycolic acid, determines the elicited inflammatory pattern
    • Vander Beken S, Dulayymi J, Naessens et al. Molecular structure of the Mycobacterium tuberculosis virulence factor, mycolic acid, determines the elicited inflammatory pattern. Eur J Immunol 2011;41:450-60
    • (2011) Eur J Immunol , Issue.41 , pp. 450-460
    • Vander Beken, S.1    Dulayymi, J.2    Naessens3
  • 41
    • 84858692080 scopus 로고    scopus 로고
    • Antigen 85C inhibition restricts Mycobacterium tuberculosis growth through disruption of cord factor biosynthesis
    • Warrier T, Tropis M, Werngren J, et al. Antigen 85C inhibition restricts Mycobacterium tuberculosis growth through disruption of cord factor biosynthesis. Antimicrob Agents Chemother 2012;56:1735-43
    • (2012) Antimicrob Agents Chemother , Issue.56 , pp. 1735-1743
    • Warrier, T.1    Tropis, M.2    Werngren, J.3
  • 42
    • 79953276682 scopus 로고    scopus 로고
    • Disruption of the SapM locus in mycobacterium bovis BCG improves its protective efficacy as a vaccine against M. tuberculosis
    • Festjens N, Bogaert P, Batni A, et al. Disruption of the SapM locus in mycobacterium bovis BCG improves its protective efficacy as a vaccine against M. tuberculosis. EMBO Mol Med 2011;3:222-34
    • (2011) EMBO Mol Med , Issue.3 , pp. 222-234
    • Festjens, N.1    Bogaert, P.2    Batni, A.3
  • 43
    • 9244234486 scopus 로고    scopus 로고
    • A Mutant of mycobacterium tuberculosis H37Rv that lacks expression of antigen 85A is attenuated in mice but retains vaccinogenic potential
    • Copenhaver RH, Sepulveda E, Armitige LY, et al. A Mutant of mycobacterium tuberculosis H37Rv that lacks expression of antigen 85A is attenuated in mice but retains vaccinogenic potential. Infect Immun 2004;72:7084-95
    • (2004) Infect Immun , vol.72 , pp. 7084-7095
    • Copenhaver, R.H.1    Sepulveda, E.2    Armitige, L.Y.3
  • 44
    • 84860502287 scopus 로고    scopus 로고
    • The fbpA/SapM double knock out strain of mycobacterium tuberculosis is highly attenuated and immunogenic in macrophages
    • Saikolappan S, Estrella J, Sasindran SJ, et al. The fbpA/SapM double knock out strain of mycobacterium tuberculosis is highly attenuated and immunogenic in macrophages. PLoS One 2012;7:e36198
    • (2012) PLoS One , Issue.7
    • Saikolappan, S.1    Estrella, J.2    Sasindran, S.J.3
  • 45
    • 84858997919 scopus 로고    scopus 로고
    • Preclinical evidence for implementing a prime-boost vaccine strategy for tuberculosis
    • BrennanMJ, Clagett B, FitzgeraldH, et al. Preclinical evidence for implementing a prime-boost vaccine strategy for tuberculosis. Vaccine 2012;30:2811-23
    • (2012) Vaccine , Issue.30 , pp. 2811-2823
    • Brennan, M.J.1    Clagett, B.2    Fitzgerald, H.3
  • 46
    • 52449104809 scopus 로고    scopus 로고
    • DNA vaccines: Ready for prime time?
    • Kutzler MA, Weiner DB. DNA vaccines: Ready for prime time? Nat Rev Genet 2008;9:776-88
    • (2008) Nat Rev Genet , vol.9 , pp. 776-788
    • Kutzler, M.A.1    Weiner, D.B.2
  • 47
    • 67449113507 scopus 로고    scopus 로고
    • Antigen load governs the differential priming of CD8+ T cells in response to BCG vaccine or M. tuberculosis
    • Ryan AA, Nambiar JK, Wozniak TM, et al. Antigen load governs the differential priming of CD8+ T cells in response to BCG vaccine or M. tuberculosis. J Immunol 2009;182:7172-7
    • (2009) J Immunol , vol.182 , pp. 7172-7177
    • Ryan, A.A.1    Nambiar, J.K.2    Wozniak, T.M.3
  • 48
    • 70249109227 scopus 로고    scopus 로고
    • DNA vaccines against mycobacterial diseases
    • Romano M, Huygen K. DNA vaccines against mycobacterial diseases. Expert Rev Vaccines 2009;8:1237-50
    • (2009) Expert Rev Vaccines , vol.8 , pp. 1237-1250
    • Romano, M.1    Huygen, K.2
  • 49
    • 33645064822 scopus 로고    scopus 로고
    • Priming but not boosting with plasmid DNA encodingmycolyl-transferase Ag85A fromM. tuberculosis increases the survival time of M. bovis BCGvaccinated mice against low dose intravenous challenge with M. tuberculosis H37Rv
    • Romano M,D'Souza S, Adnet PY, et al. Priming but not boosting with plasmid DNA encodingmycolyl-transferase Ag85A fromM. tuberculosis increases the survival time of M. bovis BCGvaccinated mice against low dose intravenous challenge with M. tuberculosis H37Rv. Vaccine 2006;24:3353-64
    • (2006) Vaccine , vol.24 , pp. 3353-3364
    • Romano, M.D.1    Souza, S.2    Adnet, P.Y.3
  • 50
    • 84858071905 scopus 로고    scopus 로고
    • Protection against mycobacterium tuberculosis challenge in mice by DNA vaccine Ag85A-ESAT-6-IL-21 priming and BCG boosting
    • Dou J, Wang Y, Yu F, et al. Protection against mycobacterium tuberculosis challenge in mice by DNA vaccine Ag85A-ESAT-6-IL-21 priming and BCG boosting. Int J Immunogenet 2012;39:183-90
    • (2012) Int J Immunogenet , Issue.39 , pp. 183-190
    • Dou, J.1    Wang, Y.2    Yu, F.3
  • 51
    • 53649109237 scopus 로고    scopus 로고
    • BCG vaccination induces poor responses against DosR regulon encoded antigens that are upregulated in latent Mycobacterium tuberculosis infection
    • Lin MY, Geluk A, Verduyn M, et al. BCG vaccination induces poor responses against DosR regulon encoded antigens that are upregulated in latent Mycobacterium tuberculosis infection. Infect Immun 2007;75:3523-30
    • (2007) Infect Immun , vol.75 , pp. 3523-3530
    • Lin, M.Y.1    Geluk, A.2    Verduyn, M.3
  • 52
    • 33846786584 scopus 로고    scopus 로고
    • Immunogenicity of eight dormancy (DosR) regulon encoded proteins of mycobacterium tuberculosis in DNA vaccinated and tuberculosisinfected mice
    • Roupie V, Romano M, Zhang L, et al. Immunogenicity of eight dormancy (DosR) regulon encoded proteins of mycobacterium tuberculosis in DNA vaccinated and tuberculosisinfected mice. Infect Immun 2007;75:941-9
    • (2007) Infect Immun , vol.75 , pp. 941-949
    • Roupie, V.1    Romano, M.2    Zhang, L.3
  • 53
    • 67650932256 scopus 로고    scopus 로고
    • Cell-mediated immune responses in tuberculosis
    • Cooper AM. Cell-mediated immune responses in tuberculosis. Annu Rev Immunol 2009;27:393-422
    • (2009) Annu Rev Immunol , vol.27 , pp. 393-422
    • Cooper, A.M.1
  • 55
    • 79551481126 scopus 로고    scopus 로고
    • Aerosol vaccines for tuberculosis: A fine line between protection and pathology
    • Hokey DA, Misra A. Aerosol vaccines for tuberculosis: A fine line between protection and pathology. Tuberculosis (Edinb) 2011;91:82-5
    • (2011) Tuberculosis (Edinb , Issue.91 , pp. 82-85
    • Hokey, D.A.1    Misra, A.2
  • 56
    • 54049113801 scopus 로고    scopus 로고
    • Airway Delivery of soluble mycobacterial antigens restores protective mucosal immunity by single intramuscular plasmid DNA tuberculosis vaccination: Role of proinflammatory signals in the lungs
    • Jeyanathan M, Mu J, Kugathasan K, et al. Airway Delivery of soluble mycobacterial antigens restores protective mucosal immunity by single intramuscular plasmid DNA tuberculosis vaccination: Role of proinflammatory signals in the lungs. J Immunol 2008;181:5618-26
    • (2008) J Immunol , vol.181 , pp. 5618-5626
    • Jeyanathan, M.1    Mu, J.2    Kugathasan, K.3
  • 58
    • 15044347334 scopus 로고    scopus 로고
    • Role of IgA in the defense against respiratory infections IgA deficient mice exhibited increased susceptibility to intranasal infection with Mycobacterium bovis BCG
    • Rodriguez A, Tjarnlund A, Ivanyi J, et al. Role of IgA in the defense against respiratory infections IgA deficient mice exhibited increased susceptibility to intranasal infection with Mycobacterium bovis BCG. Vaccine 2005;23:2565-72
    • (2005) Vaccine , vol.23 , pp. 2565-2572
    • Rodriguez, A.1    Tjarnlund, A.2    Ivanyi, J.3
  • 59
    • 79952759532 scopus 로고    scopus 로고
    • A novel human IgA monoclonal antibody protects against tuberculosis
    • Balu S, Reljic R, Lewis MJ, et al. A novel human IgA monoclonal antibody protects against tuberculosis. J Immunol 2011;186:3113-19
    • (2011) J Immunol , Issue.186 , pp. 3113-3119
    • Balu, S.1    Reljic, R.2    Lewis, M.J.3
  • 60
    • 81155131557 scopus 로고    scopus 로고
    • Simultaneous immunization against tuberculosis
    • Tchillian EZ, Ronan EO, de Lara C, et al. Simultaneous immunization against tuberculosis. PLoS One 2011;6:e27477
    • (2011) PLoS One , Issue.6
    • Tchillian, E.Z.1    Ronan, E.O.2    De Lara, C.3
  • 62
    • 9144267735 scopus 로고    scopus 로고
    • Recombinant modified vaccinia ankara expressing antigen 85A boosts BCG-primed and naturally acquired antimycobacterial immunity in humans
    • McShane H, Pathan AA, Sander C, et al. Recombinant modified vaccinia ankara expressing antigen 85A boosts BCG-primed and naturally acquired antimycobacterial immunity in humans. Nature Med 2004;10:1240-4
    • (2004) Nature Med , vol.10 , pp. 1240-1244
    • McShane, H.1    Pathan, A.A.2    Sander, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.