메뉴 건너뛰기




Volumn 41, Issue 2, 2011, Pages 450-460

Molecular structure of the Mycobacterium tuberculosis virulence factor, mycolic acid, determines the elicited inflammatory pattern

Author keywords

Alveolar macrophage; Mycobacterium tuberculosis; Mycolic acid; Pulmonary inflammation

Indexed keywords

CYCLOPROPANE; MYCOLIC ACID; VIRULENCE FACTOR;

EID: 78851469937     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201040719     Document Type: Article
Times cited : (78)

References (64)
  • 1
    • 0021035163 scopus 로고
    • Taxonomic value of Mycobacterial fatty-acids: proposal for a method of analysis
    • Daffe, M., Laneelle, M. A., Asselineau, C., Levyfrebault, V. and David, H., Taxonomic value of Mycobacterial fatty-acids: proposal for a method of analysis. Ann. Microbiol. 1983. B134: 241-256.
    • (1983) Ann. Microbiol. , vol.B134 , pp. 241-256
    • Daffe, M.1    Laneelle, M.A.2    Asselineau, C.3    Levyfrebault, V.4    David, H.5
  • 2
    • 0036045346 scopus 로고    scopus 로고
    • Current status and future development of antitubercular chemotherapy
    • Kremer, L. S. and Besra, G. S., Current status and future development of antitubercular chemotherapy. Expert Opin. Investig. Drugs 2002. 11: 1033-1049.
    • (2002) Expert Opin. Investig. Drugs , vol.11 , pp. 1033-1049
    • Kremer, L.S.1    Besra, G.S.2
  • 3
    • 0037844364 scopus 로고    scopus 로고
    • Structure, function, and biogenesis of the cell wall of Mycobacterium tuberculosis
    • Brennan, P. J., Structure, function, and biogenesis of the cell wall of Mycobacterium tuberculosis. Tuberculosis 2003. 83: 91-97.
    • (2003) Tuberculosis , vol.83 , pp. 91-97
    • Brennan, P.J.1
  • 4
    • 33751256585 scopus 로고    scopus 로고
    • Multiple roles of cord factor in the pathogenesis of primary, secondary, and cavitary tuberculosis, including a revised description of the pathology of secondary disease
    • Hunter, R. L., Olsen, M. R., Jagannath, C. and Actor, J. K., Multiple roles of cord factor in the pathogenesis of primary, secondary, and cavitary tuberculosis, including a revised description of the pathology of secondary disease. Ann. Clin. Lab. Sci. 2006. 36: 371-386.
    • (2006) Ann. Clin. Lab. Sci. , vol.36 , pp. 371-386
    • Hunter, R.L.1    Olsen, M.R.2    Jagannath, C.3    Actor, J.K.4
  • 5
    • 1642431986 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis cell envelope lipids and the host immune response
    • Karakousis, P. C., Bishai, W. R. and Dorman, S. E., Mycobacterium tuberculosis cell envelope lipids and the host immune response. Cell. Microbiol. 2004. 6: 105-116.
    • (2004) Cell. Microbiol. , vol.6 , pp. 105-116
    • Karakousis, P.C.1    Bishai, W.R.2    Dorman, S.E.3
  • 6
    • 0035663960 scopus 로고    scopus 로고
    • Immunological properties of trehalose dimycolate (cord factor) and other mycolic acid-containing glycolipids - a review
    • Ryll, R., Kumazawa, Y. and Yano, I., Immunological properties of trehalose dimycolate (cord factor) and other mycolic acid-containing glycolipids - a review. Microbiol. Immunol. 2001. 45: 801-811.
    • (2001) Microbiol. Immunol. , vol.45 , pp. 801-811
    • Ryll, R.1    Kumazawa, Y.2    Yano, I.3
  • 7
    • 45149110879 scopus 로고    scopus 로고
    • Growth of Mycobacterium tuberculosis biofilms containing free mycolic acids and harbouring drug-tolerant bacteria
    • Ojha, A. K., Baughn, A. D., Sambandan, D., Hsu, T., Trivelli, X., Guerardel, Y., Alahari, A. et al., Growth of Mycobacterium tuberculosis biofilms containing free mycolic acids and harbouring drug-tolerant bacteria. Mol. Microbiol. 2008. 69: 164-174.
    • (2008) Mol. Microbiol. , vol.69 , pp. 164-174
    • Ojha, A.K.1    Baughn, A.D.2    Sambandan, D.3    Hsu, T.4    Trivelli, X.5    Guerardel, Y.6    Alahari, A.7
  • 8
    • 77952914135 scopus 로고    scopus 로고
    • Enzymatic hydrolysis of trehalose dimycolate releases free mycolic acid during mycobacterial growth in biofilms
    • Ojha, A. K., Trivelli, X., Guerardel, Y., Kremer, L. and Hatfull, G., Enzymatic hydrolysis of trehalose dimycolate releases free mycolic acid during mycobacterial growth in biofilms. J. Biol. Chem. 2010. 285: 17380-17389.
    • (2010) J. Biol. Chem. , vol.285 , pp. 17380-17389
    • Ojha, A.K.1    Trivelli, X.2    Guerardel, Y.3    Kremer, L.4    Hatfull, G.5
  • 9
    • 15844382344 scopus 로고    scopus 로고
    • The Mycobacterium tuberculosis cell wall component mycolic acid elicits pathogen-associated host innate immune responses
    • Korf, J., Stoltz, A., Verschoor, J., De Baetselier, P. and Grooten, J., The Mycobacterium tuberculosis cell wall component mycolic acid elicits pathogen-associated host innate immune responses. Eur. J. Immunol. 2005. 35: 890-900.
    • (2005) Eur. J. Immunol. , vol.35 , pp. 890-900
    • Korf, J.1    Stoltz, A.2    Verschoor, J.3    De Baetselier, P.4    Grooten, J.5
  • 10
    • 69049108875 scopus 로고    scopus 로고
    • Foamy macrophages and the progression of the human tuberculosis granuloma
    • Russell, D. G., Cardona, P. J., Kim, M. J., Allain, S. and Altare, F., Foamy macrophages and the progression of the human tuberculosis granuloma. Nat. Immunol. 2009. 10: 943-948.
    • (2009) Nat. Immunol. , vol.10 , pp. 943-948
    • Russell, D.G.1    Cardona, P.J.2    Kim, M.J.3    Allain, S.4    Altare, F.5
  • 12
    • 0032886437 scopus 로고    scopus 로고
    • Anti-cord factor (trehalose 6,6'dimycolate) IgG antibody in tuberculosis patients recognizes mycolic acid subclasses
    • Pan, J., Fujiwara, N., Oka, S., Maekura, R., Ogura, T. and Yano, I., Anti-cord factor (trehalose 6, 6'dimycolate) IgG antibody in tuberculosis patients recognizes mycolic acid subclasses. Microbiol. Immunol. 1999. 43: 863-869.
    • (1999) Microbiol. Immunol. , vol.43 , pp. 863-869
    • Pan, J.1    Fujiwara, N.2    Oka, S.3    Maekura, R.4    Ogura, T.5    Yano, I.6
  • 13
    • 0036406815 scopus 로고    scopus 로고
    • Prevalence of anti-mycolic acid antibodies in patients with pulmonary tuberculosis co-infected with HIV
    • Schleicher, G. K., Feldman, C., Vermaak, Y. and Verschoor, J. A., Prevalence of anti-mycolic acid antibodies in patients with pulmonary tuberculosis co-infected with HIV. Clin. Chem. Lab. Med. 2002. 40: 882-887.
    • (2002) Clin. Chem. Lab. Med. , vol.40 , pp. 882-887
    • Schleicher, G.K.1    Feldman, C.2    Vermaak, Y.3    Verschoor, J.A.4
  • 14
    • 0035987344 scopus 로고    scopus 로고
    • Location of functional groups in mycobacterial meromycolate chains; the recognition of new structural principles in mycolic acids
    • Watanabe, M., Aoyagi, Y., Mitome, H., Fujita, T., Naoki, H., Ridell, M. and Minnikin, D. E., Location of functional groups in mycobacterial meromycolate chains; the recognition of new structural principles in mycolic acids. Microbiology 2002. 148: 1881-1902.
    • (2002) Microbiology , vol.148 , pp. 1881-1902
    • Watanabe, M.1    Aoyagi, Y.2    Mitome, H.3    Fujita, T.4    Naoki, H.5    Ridell, M.6    Minnikin, D.E.7
  • 15
    • 0034924433 scopus 로고    scopus 로고
    • Separation and characterization of individual mycolic acids in representative mycobacteria
    • Watanabe, M., Aoyagi, Y., Ridell, M. and Minnikin, D. E., Separation and characterization of individual mycolic acids in representative mycobacteria. Microbiology (Reading, England) 2001. 147: 1825-1837.
    • (2001) Microbiology (Reading, England) , vol.147 , pp. 1825-1837
    • Watanabe, M.1    Aoyagi, Y.2    Ridell, M.3    Minnikin, D.E.4
  • 17
    • 0018648998 scopus 로고
    • Major mycolic acids of Mycobacterium-Smegmatis - characterization of their homologous series
    • Wong, M. Y. H., Steck, P. A. and Gray, G. R., Major mycolic acids of Mycobacterium-Smegmatis - characterization of their homologous series. J. Biol. Chem. 1979. 254: 5734-5740.
    • (1979) J. Biol. Chem. , vol.254 , pp. 5734-5740
    • Wong, M.Y.H.1    Steck, P.A.2    Gray, G.R.3
  • 18
    • 0000900934 scopus 로고
    • Methoxymycolic and ketomycolic acids from human Tubercle Bacilli
    • Minnikin, D. E. and Polgar, N., Methoxymycolic and ketomycolic acids from human Tubercle Bacilli. Chem. Commun. 1967. 22: 1172-1174.
    • (1967) Chem. Commun. , vol.22 , pp. 1172-1174
    • Minnikin, D.E.1    Polgar, N.2
  • 19
    • 0022966194 scopus 로고
    • Mycolic acid analysis for clinical-identification of Mycobacterium-Avium and related Mycobacteria
    • Levyfrebault, V., Goh, K. S. and David, H. L., Mycolic acid analysis for clinical-identification of Mycobacterium-Avium and related Mycobacteria. J. Clin. Microbiol. 1986. 24: 835-839.
    • (1986) J. Clin. Microbiol. , vol.24 , pp. 835-839
    • Levyfrebault, V.1    Goh, K.S.2    David, H.L.3
  • 20
    • 0034073375 scopus 로고    scopus 로고
    • Oxygenated mycolic acids are necessary for virulence of Mycobacterium tuberculosis in mice
    • Dubnau, E., Chan, J., Raynaud, C., Mohan, V. P., Laneelle, M. A., Yu, K. M., Quemard, A. et al., Oxygenated mycolic acids are necessary for virulence of Mycobacterium tuberculosis in mice. Mol. Microbiol. 2000. 36: 630-637.
    • (2000) Mol. Microbiol. , vol.36 , pp. 630-637
    • Dubnau, E.1    Chan, J.2    Raynaud, C.3    Mohan, V.P.4    Laneelle, M.A.5    Yu, K.M.6    Quemard, A.7
  • 21
    • 33847797216 scopus 로고    scopus 로고
    • Liposome-based drug delivery to alveolar macrophages
    • Vyas, S. P. and Khatri, K., Liposome-based drug delivery to alveolar macrophages. Expert Opin. Drug Deliv. 2007. 4: 95-99.
    • (2007) Expert Opin. Drug Deliv. , vol.4 , pp. 95-99
    • Vyas, S.P.1    Khatri, K.2
  • 22
    • 0030953845 scopus 로고    scopus 로고
    • Analysis of the local kinetics and localization of interleukin-1 alpha, tumour necrosis factor-alpha and transforming growth factor-beta, during the course of experimental pulmonary tuberculosis
    • Hernandez-Pando, R., Orozco, H., Arriaga, K., Sampieri, A., Larriva-Sahd, J. and Madrid-Marina, V., Analysis of the local kinetics and localization of interleukin-1 alpha, tumour necrosis factor-alpha and transforming growth factor-beta, during the course of experimental pulmonary tuberculosis. Immunology 1997. 90: 607-617.
    • (1997) Immunology , vol.90 , pp. 607-617
    • Hernandez-Pando, R.1    Orozco, H.2    Arriaga, K.3    Sampieri, A.4    Larriva-Sahd, J.5    Madrid-Marina, V.6
  • 23
    • 48449094384 scopus 로고    scopus 로고
    • A role for tumour necrosis factor-alpha, complement C5 and interleukin-6 in the initiation and development of the mycobacterial cord factor trehalose 6,6'-dimycolate induced granulomatous response
    • Welsh, K. J., Abbott, A. N., Hwang, S. A., Indrigo, J., Armitige, L. Y., Blackburn, M. R., Hunter, R. L., Jr., and Actor, J. K., A role for tumour necrosis factor-alpha, complement C5 and interleukin-6 in the initiation and development of the mycobacterial cord factor trehalose 6, 6'-dimycolate induced granulomatous response. Microbiology (Reading, England) 2008. 154: 1813-1824.
    • (2008) Microbiology (Reading, England) , vol.154 , pp. 1813-1824
    • Welsh, K.J.1    Abbott, A.N.2    Hwang, S.A.3    Indrigo, J.4    Armitige, L.Y.5    Blackburn, M.R.6    Hunter, R.L.7    Actor, J.K.8
  • 24
    • 20044387192 scopus 로고    scopus 로고
    • Macrophage galactose-type C-type lectins as novel markers for alternatively activated macrophages elicited by parasitic infections and allergic airway inflammation
    • Raes, G., Brys, L., Dahal, B. K., Brandt, J., Grooten, J., Brombacher, F., Vanham, G. et al., Macrophage galactose-type C-type lectins as novel markers for alternatively activated macrophages elicited by parasitic infections and allergic airway inflammation. J. Leukoc. Biol. 2005. 77: 321-327.
    • (2005) J. Leukoc. Biol. , vol.77 , pp. 321-327
    • Raes, G.1    Brys, L.2    Dahal, B.K.3    Brandt, J.4    Grooten, J.5    Brombacher, F.6    Vanham, G.7
  • 25
    • 67650485985 scopus 로고    scopus 로고
    • Alternative activation of macrophages: An immunologic functional perspective
    • Martinez, F. O., Helming, L. and Gordon, S., Alternative activation of macrophages: An immunologic functional perspective. Annu. Rev. Immunol. 2009. 27: 451-483.
    • (2009) Annu. Rev. Immunol. , vol.27 , pp. 451-483
    • Martinez, F.O.1    Helming, L.2    Gordon, S.3
  • 27
    • 0036015838 scopus 로고    scopus 로고
    • The methyl-branched fortifications of Mycobacterium tuberculosis
    • Minnikin, D. E., Kremer, L., Dover, L. G. and Besra, G. S., The methyl-branched fortifications of Mycobacterium tuberculosis. Chem. Biol. 2002. 9: 545-553.
    • (2002) Chem. Biol. , vol.9 , pp. 545-553
    • Minnikin, D.E.1    Kremer, L.2    Dover, L.G.3    Besra, G.S.4
  • 28
    • 78851471001 scopus 로고
    • Structure and distribution of mycolic acids of Mycobacteria
    • Minnikin, D. E., Kusamran, K. and Polgar, N., Structure and distribution of mycolic acids of Mycobacteria. J. Gen. Microbiol. 1971. 68: iii-iv.
    • (1971) J. Gen. Microbiol. , vol.68
    • Minnikin, D.E.1    Kusamran, K.2    Polgar, N.3
  • 29
    • 78851472486 scopus 로고
    • Nuclear magnetic-resonance studies on the mycolic acids
    • Minnikin, D. E. and Minnikin, S. M., Nuclear magnetic-resonance studies on the mycolic acids. J. Am. Oil Chem. Soc. 1980. 57: A163-A163.
    • (1980) J. Am. Oil Chem. Soc. , vol.57
    • Minnikin, D.E.1    Minnikin, S.M.2
  • 30
    • 0013913967 scopus 로고
    • Studies on the mycolic acids from human tubercle bacilli
    • Minnikin, D. E. and Polgar, N., Studies on the mycolic acids from human tubercle bacilli. Tetrahedron Lett. 1966. 23: 2643-2647.
    • (1966) Tetrahedron Lett. , vol.23 , pp. 2643-2647
    • Minnikin, D.E.1    Polgar, N.2
  • 31
    • 4244015073 scopus 로고
    • Stereochemical studies on mycolic acids
    • Minnikin, D. E. and Polgar, N., Stereochemical studies on mycolic acids. Chem. Commun. 1966. 18: 648-649.
    • (1966) Chem. Commun. , vol.18 , pp. 648-649
    • Minnikin, D.E.1    Polgar, N.2
  • 32
    • 37049119478 scopus 로고
    • Mycolic Acids from Human and Avian Tubercle Bacilli
    • Minnikin, D. E. and Polgar, N., Mycolic Acids from Human and Avian Tubercle Bacilli. Chem. Commun. 1967. 18: 916-918.
    • (1967) Chem. Commun. , vol.18 , pp. 916-918
    • Minnikin, D.E.1    Polgar, N.2
  • 33
    • 37049133945 scopus 로고
    • Structural Studies on Mycolic Acids
    • Minnikin, D. E. and Polgar, N., Structural Studies on Mycolic Acids. Chem. Commun. 1967. 7: 312-314.
    • (1967) Chem. Commun. , vol.7 , pp. 312-314
    • Minnikin, D.E.1    Polgar, N.2
  • 34
    • 24044458848 scopus 로고    scopus 로고
    • Temperature dependence of the Langmuir monolayer packing of mycolic acids from Mycobacterium tuberculosis
    • Villeneuve, M., Kawai, M., Kanashima, H., Watanabe, M., Minnikin, D. E. and Nakahara, H., Temperature dependence of the Langmuir monolayer packing of mycolic acids from Mycobacterium tuberculosis. Biochim. Biophys. Acta 2005. 1715: 71-80.
    • (2005) Biochim. Biophys. Acta , vol.1715 , pp. 71-80
    • Villeneuve, M.1    Kawai, M.2    Kanashima, H.3    Watanabe, M.4    Minnikin, D.E.5    Nakahara, H.6
  • 35
    • 65749086909 scopus 로고    scopus 로고
    • Mycolic acid cyclopropanation is essential for viability, drug resistance, and cell wall integrity of Mycobacterium tuberculosis
    • Barkan, D., Liu, Z., Sacchettini, J. C. and Glickman, M. S., Mycolic acid cyclopropanation is essential for viability, drug resistance, and cell wall integrity of Mycobacterium tuberculosis. Chem. Biol. 2009. 16: 499-509.
    • (2009) Chem. Biol. , vol.16 , pp. 499-509
    • Barkan, D.1    Liu, Z.2    Sacchettini, J.C.3    Glickman, M.S.4
  • 36
    • 34247572374 scopus 로고    scopus 로고
    • Deletion of kasB in Mycobacterium tuberculosis causes loss of acid-fastness and subclinical latent tuberculosis in immunocompetent mice
    • Bhatt, A., Fujiwara, N., Bhatt, K., Gurcha, S. S., Kremer, L., Chen, B., Chan, J. et al., Deletion of kasB in Mycobacterium tuberculosis causes loss of acid-fastness and subclinical latent tuberculosis in immunocompetent mice. Proc. Natl. Acad. Sci. USA 2007. 104: 5157-5162.
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 5157-5162
    • Bhatt, A.1    Fujiwara, N.2    Bhatt, K.3    Gurcha, S.S.4    Kremer, L.5    Chen, B.6    Chan, J.7
  • 38
    • 0141677776 scopus 로고    scopus 로고
    • Requirement for kasB in Mycobacterium mycolic acid biosynthesis, cell wall impermeability and intracellular survival: implications for therapy
    • Gao, L. Y., Laval, F., Lawson, E. H., Groger, R. K., Woodruff, A., Morisaki, J. H., Cox, J. S. et al., Requirement for kasB in Mycobacterium mycolic acid biosynthesis, cell wall impermeability and intracellular survival: implications for therapy. Mol. Microbiol. 2003. 49: 1547-1563.
    • (2003) Mol. Microbiol. , vol.49 , pp. 1547-1563
    • Gao, L.Y.1    Laval, F.2    Lawson, E.H.3    Groger, R.K.4    Woodruff, A.5    Morisaki, J.H.6    Cox, J.S.7
  • 39
    • 0037424531 scopus 로고    scopus 로고
    • The mmaA2 gene of Mycobacterium tuberculosis encodes the distal cyclopropane synthase of the alpha-mycolic acid
    • Glickman, M. S., The mmaA2 gene of Mycobacterium tuberculosis encodes the distal cyclopropane synthase of the alpha-mycolic acid. J. Biol. Chem. 2003. 278: 7844-7849.
    • (2003) J. Biol. Chem. , vol.278 , pp. 7844-7849
    • Glickman, M.S.1
  • 40
    • 0033634971 scopus 로고    scopus 로고
    • A novel mycolic acid cyclopropane synthetase is required for cording, persistence, and virulence of Mycobacterium tuberculosis
    • Glickman, M. S., Cox, J. S. and Jacobs, W. R., A novel mycolic acid cyclopropane synthetase is required for cording, persistence, and virulence of Mycobacterium tuberculosis. Mol. Cell 2000. 5: 717-727.
    • (2000) Mol. Cell , vol.5 , pp. 717-727
    • Glickman, M.S.1    Cox, J.S.2    Jacobs, W.R.3
  • 41
    • 14244260489 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis controls host innate immune activation through cyclopropane modification of a glycolipid effector molecule
    • Rao, V., Fujiwara, N., Porcelli, S. A. and Glickman, M. S., Mycobacterium tuberculosis controls host innate immune activation through cyclopropane modification of a glycolipid effector molecule. J. Exp. Med. 2005. 201: 535-543.
    • (2005) J. Exp. Med. , vol.201 , pp. 535-543
    • Rao, V.1    Fujiwara, N.2    Porcelli, S.A.3    Glickman, M.S.4
  • 42
    • 33745217856 scopus 로고    scopus 로고
    • Trans-cyclopropanation of mycolic acids on trehalose dimycolate suppresses Mycobacterium tuberculosis-induced inflammation and virulence
    • Rao, V., Gao, F., Chen, B., Jacobs, W. R., Jr., and Glickman, M. S., Trans-cyclopropanation of mycolic acids on trehalose dimycolate suppresses Mycobacterium tuberculosis-induced inflammation and virulence. J. Clin. Invest. 2006. 116: 1660-1667.
    • (2006) J. Clin. Invest. , vol.116 , pp. 1660-1667
    • Rao, V.1    Gao, F.2    Chen, B.3    Jacobs, W.R.4    Glickman, M.S.5
  • 43
    • 12844278679 scopus 로고    scopus 로고
    • Pathway to synthesis and processing of mycolic acids in Mycobacterium tuberculosis
    • Takayama, K., Wang, C. and Besra, G. S., Pathway to synthesis and processing of mycolic acids in Mycobacterium tuberculosis. Clin. Microbiol. Rev. 2005. 18: 81-101.
    • (2005) Clin. Microbiol. Rev. , vol.18 , pp. 81-101
    • Takayama, K.1    Wang, C.2    Besra, G.S.3
  • 44
    • 0031694056 scopus 로고    scopus 로고
    • The effect of oxygenated mycolic acid composition on cell wall function and macrophage growth in Mycobacterium tuberculosis
    • Yuan, Y., Zhu, Y., Crane, D. D. and Barry, C. E., 3rd., The effect of oxygenated mycolic acid composition on cell wall function and macrophage growth in Mycobacterium tuberculosis. Mol. Microbiol. 1998. 29: 1449-1458.
    • (1998) Mol. Microbiol. , vol.29 , pp. 1449-1458
    • Yuan, Y.1    Zhu, Y.2    Crane, D.D.3    Barry, C.E.4
  • 45
    • 33748645974 scopus 로고    scopus 로고
    • Is the mycobacterial cell wall a hopeless drug target for latent tuberculosis?
    • Boshoff, H. I. and Barry Iii, C. E., Is the mycobacterial cell wall a hopeless drug target for latent tuberculosis? Drug Discov. Today Dis. Mech. 2006. 3: 237-245.
    • (2006) Drug Discov. Today Dis. Mech. , vol.3 , pp. 237-245
    • Boshoff, H.I.1    Barry Iii, C.E.2
  • 46
    • 57149096869 scopus 로고    scopus 로고
    • Foamy macrophages from tuberculous patients' granulomas constitute a nutrient-rich reservoir for M. tuberculosis persistence
    • e1000204.
    • Peyron, P., Vaubourgeix, J., Poquet, Y., Levillain, F., Botanch, C., Bardou, F., Daffe, M. et al., Foamy macrophages from tuberculous patients' granulomas constitute a nutrient-rich reservoir for M. tuberculosis persistence. PLoS Pathog. 2008. 4: e1000204.
    • (2008) PLoS Pathog. , vol.4
    • Peyron, P.1    Vaubourgeix, J.2    Poquet, Y.3    Levillain, F.4    Botanch, C.5    Bardou, F.6    Daffe, M.7
  • 47
    • 0034596455 scopus 로고    scopus 로고
    • The synthesis of single enantiomers of a meromycolic acid
    • Al Dulayymi, J. R., Baird, M. S. and Roberts, E., The synthesis of single enantiomers of a meromycolic acid. Tetrahedron Lett. 2000. 41: 7107-7110.
    • (2000) Tetrahedron Lett. , vol.41 , pp. 7107-7110
    • Al Dulayymi, J.R.1    Baird, M.S.2    Roberts, E.3
  • 48
    • 0037244370 scopus 로고    scopus 로고
    • The synthesis of a single enantiomer of a major alpha-mycolic acid of Mycobacterium tuberculosis
    • Al Dulayymi, J. R., Baird, M. S. and Roberts, E., The synthesis of a single enantiomer of a major alpha-mycolic acid of Mycobacterium tuberculosis. Chem. Commun. 2003. 228-229.
    • (2003) Chem. Commun. , pp. 228-229
    • Al Dulayymi, J.R.1    Baird, M.S.2    Roberts, E.3
  • 49
    • 27844453864 scopus 로고    scopus 로고
    • The synthesis of a single enantiomer of a major alpha-mycolic acid of M-tuberculosis
    • Al Dulayymi, J. R., Baird, M. S. and Roberts, E., The synthesis of a single enantiomer of a major alpha-mycolic acid of M-tuberculosis. Tetrahedron 2005. 61: 11939-11951.
    • (2005) Tetrahedron , vol.61 , pp. 11939-11951
    • Al Dulayymi, J.R.1    Baird, M.S.2    Roberts, E.3
  • 50
    • 33846922093 scopus 로고    scopus 로고
    • The first syntheses of single enantiomers of the major methoxymycolic acid of Mycobacterium tuberculosis
    • Al Dulayymi, J. R., Baird, M. S., Roberts, E., Deysel, M. and Verschoor, J., The first syntheses of single enantiomers of the major methoxymycolic acid of Mycobacterium tuberculosis. Tetrahedron 2007. 63: 2571-2592.
    • (2007) Tetrahedron , vol.63 , pp. 2571-2592
    • Al Dulayymi, J.R.1    Baird, M.S.2    Roberts, E.3    Deysel, M.4    Verschoor, J.5
  • 51
    • 33750738531 scopus 로고    scopus 로고
    • The synthesis of single enantiomers of meromycolic acids from mycobacterial wax esters
    • Al Dulayymi, J. R., Baird, M. S., Roberts, E. and Minnikin, D. E., The synthesis of single enantiomers of meromycolic acids from mycobacterial wax esters. Tetrahedron 2006. 62: 11867-11880.
    • (2006) Tetrahedron , vol.62 , pp. 11867-11880
    • Al Dulayymi, J.R.1    Baird, M.S.2    Roberts, E.3    Minnikin, D.E.4
  • 53
    • 33646070297 scopus 로고    scopus 로고
    • The synthesis of one enantiomer of the alpha-methyl-trans-cyclopropane unit of mycolic acids
    • Al-Dulayymi, J. R., Baird, M. S., Mohammed, H., Roberts, E. and Clegg, W., The synthesis of one enantiomer of the alpha-methyl-trans-cyclopropane unit of mycolic acids. Tetrahedron 2006. 62: 4851-4862.
    • (2006) Tetrahedron , vol.62 , pp. 4851-4862
    • Al-Dulayymi, J.R.1    Baird, M.S.2    Mohammed, H.3    Roberts, E.4    Clegg, W.5
  • 54
    • 0345791445 scopus 로고    scopus 로고
    • Synthesis and properties of methyl 5-(1' R,2' S)-(2-octadecylcycloprop-1-yl)pentanoate and other omega-19 chiral cyclopropane fatty acids and esters related to mycobacterial mycolic acids
    • Coxon, G. D., Al Dulayymi, J. R., Morehouse, C., Brennan, P. J., Besra, G. S., Baird, M. S. and Minnikin, D. E., Synthesis and properties of methyl 5-(1' R, 2' S)-(2-octadecylcycloprop-1-yl)pentanoate and other omega-19 chiral cyclopropane fatty acids and esters related to mycobacterial mycolic acids. Chem. Phys. Lipids 2004. 127: 35-46.
    • (2004) Chem. Phys. Lipids , vol.127 , pp. 35-46
    • Coxon, G.D.1    Al Dulayymi, J.R.2    Morehouse, C.3    Brennan, P.J.4    Besra, G.S.5    Baird, M.S.6    Minnikin, D.E.7
  • 56
    • 33847077227 scopus 로고    scopus 로고
    • The first synthesis of single enantiomers of ketomycolic acids
    • Koza, G. and Baird, M. S., The first synthesis of single enantiomers of ketomycolic acids. Tetrahedron Lett. 2007. 48: 2165-2169.
    • (2007) Tetrahedron Lett. , vol.48 , pp. 2165-2169
    • Koza, G.1    Baird, M.S.2
  • 57
    • 70449129831 scopus 로고    scopus 로고
    • The synthesis of single enantiomers of trans-alkene-containing mycolic acids
    • Koza, G., Rowles, R., Theunissen, C., Al-Dulayymi, J. R. and Baird, M. S., The synthesis of single enantiomers of trans-alkene-containing mycolic acids. Tetrahedron Lett. 2009. 50: 7259-7262.
    • (2009) Tetrahedron Lett. , vol.50 , pp. 7259-7262
    • Koza, G.1    Rowles, R.2    Theunissen, C.3    Al-Dulayymi, J.R.4    Baird, M.S.5
  • 58
    • 70350517433 scopus 로고    scopus 로고
    • The synthesis of single enantiomers of mycobacterial ketomycolic acids containing cis-cyclopropanes
    • Koza, G., Theunissen, C., Al Dulayymi, J. R. and Baird, M. S., The synthesis of single enantiomers of mycobacterial ketomycolic acids containing cis-cyclopropanes. Tetrahedron 2009. 65: 10214-10229.
    • (2009) Tetrahedron , vol.65 , pp. 10214-10229
    • Koza, G.1    Theunissen, C.2    Al Dulayymi, J.R.3    Baird, M.S.4
  • 59
    • 33745221673 scopus 로고    scopus 로고
    • Of mice, men, and elephants: Mycobacterium tuberculosis cell envelope lipids and pathogenesis
    • Riley, L. W., Of mice, men, and elephants: Mycobacterium tuberculosis cell envelope lipids and pathogenesis. J. Clin. Invest. 2006. 116: 1475-1478.
    • (2006) J. Clin. Invest. , vol.116 , pp. 1475-1478
    • Riley, L.W.1
  • 60
    • 33645450141 scopus 로고    scopus 로고
    • Trehalose 6,6'-dimycolate and lipid in the pathogenesis of caseating granulomas of tuberculosis in mice
    • Hunter, R. L., Olsen, M., Jagannath, C. and Actor, J. K., Trehalose 6, 6'-dimycolate and lipid in the pathogenesis of caseating granulomas of tuberculosis in mice. Am. J. Pathol. 2006. 168: 1249-1261.
    • (2006) Am. J. Pathol. , vol.168 , pp. 1249-1261
    • Hunter, R.L.1    Olsen, M.2    Jagannath, C.3    Actor, J.K.4
  • 61
    • 77951932177 scopus 로고    scopus 로고
    • Cutting edge: Mincle is essential for recognition and adjuvanticity of the mycobacterial cord factor and its synthetic analog trehalose-dibehenate
    • Schoenen, H., Bodendorfer, B., Hitchens, K., Manzanero, S., Werninghaus, K., Nimmerjahn, F., Agger, E. M. et al., Cutting edge: Mincle is essential for recognition and adjuvanticity of the mycobacterial cord factor and its synthetic analog trehalose-dibehenate. J. Immunol. 184: 2756-2760.
    • J. Immunol , vol.184 , pp. 2756-2760
    • Schoenen, H.1    Bodendorfer, B.2    Hitchens, K.3    Manzanero, S.4    Werninghaus, K.5    Nimmerjahn, F.6    Agger, E.M.7
  • 64
    • 2942617055 scopus 로고    scopus 로고
    • A rapid flow cytometric method for determining the cellular composition of bronchoalveolar lavage fluid cells in mouse models of asthma
    • van Rijt, L. S., Kuipers, H., Vos, N., Hijdra, D., Hoogsteden, H. C. and Lambrecht, B. N., A rapid flow cytometric method for determining the cellular composition of bronchoalveolar lavage fluid cells in mouse models of asthma. J. Immunol. Methods 2004. 288: 111-121.
    • (2004) J. Immunol. Methods , vol.288 , pp. 111-121
    • van Rijt, L.S.1    Kuipers, H.2    Vos, N.3    Hijdra, D.4    Hoogsteden, H.C.5    Lambrecht, B.N.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.