Mycolic acid modification by the mmaA4 gene of M. tuberculosis modulates IL-12 production

PLoS Pathogens

Volumn 4, Issue 6, 2008, Pages

  Dao, Dee N ^a   Sweeney, Kari ^a   Hsu, Tsungda ^a   Gurcha, Sudagar S ^b   Nascimento, Ivan P ^c   Roshevsky, Dan ^a   Besra, Gurdyal S ^b   Chan, John ^a   Porcelli, Steven A ^a   Jacobs Jr , William R ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^c INSTITUTO BUTANTAN   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

CORD FACTOR; INTERLEUKIN 12; INTERLEUKIN 12P40; METHYLTRANSFERASE; MYCOLIC ACID; TUMOR NECROSIS FACTOR ALPHA; BACTERIAL PROTEIN; MIXED FUNCTION OXIDASE; MMA4 PROTEIN, MYCOBACTERIUM TUBERCULOSSIS;

ADOLESCENT; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BACTERIAL GENE; BACTERIAL VIRULENCE; BACTERIUM MUTANT; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; GENE IDENTIFICATION; GENETIC TRANSCRIPTION; IMMUNE SYSTEM; MACROPHAGE; MALE; MMAA4 GENE; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; REPORTER GENE; TRANSPOSON; ANIMAL; BAGG ALBINO MOUSE; BIOSYNTHESIS; BONE MARROW CELL; CELL CULTURE; ENZYMOLOGY; GENETICS; IMMUNITY; IMMUNOLOGY; METABOLISM; MUTATION; PATHOGENICITY; PHYSIOLOGY; VIROLOGY;

MUS; MYCOBACTERIUM TUBERCULOSIS;

ANIMALS; BACTERIAL PROTEINS; BONE MARROW CELLS; CELLS, CULTURED; FEMALE; IMMUNITY; INTERLEUKIN-12 SUBUNIT P40; MACROPHAGES; METHYLTRANSFERASES; MICE; MICE, INBRED BALB C; MIXED FUNCTION OXYGENASES; MUTATION; MYCOBACTERIUM TUBERCULOSIS; MYCOLIC ACIDS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 46449096343     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1000081     Document Type: Article

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