Fluorogenic quantum dot-gold nanoparticle assembly for beta secretase inhibitor screening in live cell

Analytical Chemistry

Volumn 84, Issue 20, 2012, Pages 8595-8601

  Choi, Youngseon ^a,c   Cho, Yoojin ^a,d   Kim, Minjung ^a   Grailhe, Regis ^b   Song, Rita ^a  

^a Institute Pasteur Korea   (South Korea)

^b Institut Pasteur Korea IP K   (South Korea)

^c NONE   (South Korea)

^d Drug Biology Group   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE MOLECULES; ALZHEIMER'S DISEASE; AU NANOPARTICLE; CDSE/ZNS; CELL-BASED ASSAYS; DRUG SCREENING; ENZYMATIC DIGESTIONS; FLUORESCENCE RESONANCE ENERGY TRANSFER; FLUORESCENCE SIGNALS; FLUOROGENICS; HIGH THROUGHPUT SYSTEMS; IN-VITRO; INHIBITORY CONCENTRATION; LIVE CELL; LIVING CELL; NANOPARTICLE ASSEMBLIES; POTENTIAL APPLICATIONS; QUENCHING EFFICIENCY; SECRETASES; SUBSTRATE PEPTIDES;

AMINO ACIDS; DIAGNOSIS; ENERGY TRANSFER; FLUORESCENCE; NANOPARTICLES; QUENCHING; SEMICONDUCTOR QUANTUM DOTS;

GOLD;

ASPARTIC PROTEINASE; BACE1 PROTEIN, HUMAN; ENZYME INHIBITOR; FLUORESCENT DYE; GOLD; NANOPARTICLE; PEPTIDE; QUANTUM DOT; SECRETASE;

AMINO ACID SEQUENCE; ARTICLE; CELL STRAIN HEK293; CHEMISTRY; DRUG ANTAGONISM; DRUG SCREENING; FLUORESCENCE RESONANCE ENERGY TRANSFER; HUMAN; METABOLISM; METHODOLOGY; MOLECULAR GENETICS;

AMINO ACID SEQUENCE; AMYLOID PRECURSOR PROTEIN SECRETASES; ASPARTIC ACID ENDOPEPTIDASES; DRUG EVALUATION, PRECLINICAL; ENZYME INHIBITORS; FLUORESCENCE RESONANCE ENERGY TRANSFER; FLUORESCENT DYES; GOLD; HEK293 CELLS; HUMANS; MOLECULAR SEQUENCE DATA; NANOPARTICLES; PEPTIDES; QUANTUM DOTS;

EID: 84869418570     PISSN: 00032700     EISSN: 15206882     Source Type: Journal    
DOI: 10.1021/ac301574b     Document Type: Article

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