Autophagy is a cell self-protective mechanism against arsenic-induced cell transformation

Toxicological Sciences

Volumn 130, Issue 2, 2012, Pages 298-308

  Zhang, Tao ^a,b   Qi, Yuanlin ^a,b   Liao, Mingjun ^a   Xu, Mei ^a   Bower, Kimberley A ^a   Frank, Jacqueline A ^a   Shen, Han Ming ^c   Luo, Jia ^a   Shi, Xianglin ^a   Chen, Gang ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

^b FUJIAN MEDICAL UNIVERSITY   (China)

^c NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Arsenic; Autophagy; Oxidative stress; Transformation; Tumorigenesis

Indexed keywords

ARSENIC; COPPER ZINC SUPEROXIDE DISMUTASE; MAMMALIAN TARGET OF RAPAMYCIN; MICROTUBULE ASSOCIATED PROTEIN 1; REACTIVE OXYGEN METABOLITE; WORTMANNIN;

ARTICLE; AUTOPHAGY; CARCINOGENESIS; CELL PROTECTION; CELL TRANSFORMATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DOWN REGULATION; EXPOSURE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; LIGHT CHAIN; MALE; MITOCHONDRION; MOUSE; NONHUMAN; PROTEIN EXPRESSION; TUMOR VOLUME; UPREGULATION;

ANIMALS; ARSENITES; AUTOPHAGY; CELL LINE; CELL TRANSFORMATION, NEOPLASTIC; EPITHELIAL CELLS; HUMANS; LUNG NEOPLASMS; MALE; MICE; MICE, NUDE; MICROTUBULE-ASSOCIATED PROTEINS; MITOCHONDRIA; OXIDATIVE STRESS; PROTEIN KINASE INHIBITORS; REACTIVE OXYGEN SPECIES; RESPIRATORY MUCOSA; SIGNAL TRANSDUCTION; SIROLIMUS; SODIUM COMPOUNDS; TIME FACTORS; TOR SERINE-THREONINE KINASES; TRANSFECTION; TUMOR BURDEN;

MAMMALIA;

EID: 84869393183     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfs240     Document Type: Article

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