TIS21/BTG2/PC3 accelerates the repair of DNA double strand breaks by enhancing Mre11 methylation and blocking damage signal transfer to the Chk2T68-p53S20 pathway

DNA Repair

Volumn 11, Issue 12, 2012, Pages 965-975

  Choi, Kyu Sung ^a   Kim, Ji Yeon ^a   Lim, Seo Kyung ^a   Choi, Yong Won ^a   Kim, Young Hwa ^a   Kang, So Young ^a   Park, Tae Jun ^a   Lim, In Kyoung ^a  

^a Ajou University School of Medicine   (South Korea)

Author keywords

ATM; Chk2; Chk2T68; DNA damage; DSBs; Mre11; Mre11 methylation; MRN complex; P53S20; PRMT1; Rad50; TIS21; TIS21 MEF; TIS21 BTG2 PC3; Wt MEF

Indexed keywords

ATM PROTEIN; CASPASE 3; CASPASE 7; CHECKPOINT KINASE 2; COMPLEMENTARY DNA; CYCLIN E; CYCLINE; DNA; DOUBLE STRANDED DNA; ETOPOSIDE; PROTEIN BAX; PROTEIN P53; TRANSCRIPTION FACTOR E2F1;

ADENOVIRUS; ANIMAL CELL; APOPTOSIS; ARTICLE; AUTORADIOGRAPHY; CELL LYSATE; COMET ASSAY; DNA DAMAGE; DNA METHYLATION; DNA STRAND BREAKAGE; EMBRYO; ENZYME ASSAY; ENZYME INHIBITION; FLUORESCENCE ACTIVATED CELL SORTER; GENE EXPRESSION; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOCYTOCHEMISTRY; IMMUNOPRECIPITATION; ISOTOPE LABELING; MOUSE; MULTIGENE FAMILY; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TIS21 GENE; TUMOR CELL;

ADENOVIRIDAE; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CLONING, MOLECULAR; COMET ASSAY; DNA BREAKS, DOUBLE-STRANDED; DNA METHYLATION; DNA REPAIR; DNA-BINDING PROTEINS; E2F1 TRANSCRIPTION FACTOR; ENZYME ACTIVATION; ETOPOSIDE; GENETIC VECTORS; HEK293 CELLS; HELA CELLS; HISTONES; HUMANS; IMMEDIATE-EARLY PROTEINS; PHOSPHORYLATION; PROTEIN-ARGININE N-METHYLTRANSFERASES; PROTEIN-SERINE-THREONINE KINASES; REPRESSOR PROTEINS; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS;

EID: 84869199434     PISSN: 15687864     EISSN: 15687856     Source Type: Journal    
DOI: 10.1016/j.dnarep.2012.09.009     Document Type: Article

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