Mutations in the M-gene segment can substantially increase replication efficiency of NS1 deletion influenza a virus in MDCK cells

Journal of Virology

Volumn 86, Issue 22, 2012, Pages 12341-12350

  van Wielink, R ^a   Harmsen, M M ^a   Martens, D E ^a   Peeters, B P H ^a   Wijffels, R H ^a   Moormanna, R J M ^a  

^a WAGENINGEN UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; MESSENGER RNA; NONSTRUCTURAL PROTEIN 1; PROTEIN M1; PROTEIN M2; UNCLASSIFIED DRUG; VIRUS PROTEIN;

AMINO ACID SUBSTITUTION; ARTICLE; CELL STRAIN; CELLULAR DISTRIBUTION; CONTROLLED STUDY; EMBRYO; EVOLUTIONARY ADAPTATION; GENE CLUSTER; GENE DELETION; GENE FUNCTION; GENE SEQUENCE; HUMAN; HUMAN CELL; INFLUENZA A; INFLUENZA VIRUS A; M1 GENE; M2 GENE; MUTATIONAL ANALYSIS; NONHUMAN; NP GENE; NS1 GENE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; RNA EDITING; RNA SPLICING; SEQUENCE ANALYSIS; VIRUS CELL INTERACTION; VIRUS GENE; VIRUS REPLICATION; VIRUS STRAIN;

ANIMALS; APOPTOSIS; BASE SEQUENCE; CERCOPITHECUS AETHIOPS; DOGS; GENOME, VIRAL; HUMANS; INFLUENZA A VIRUS; INFLUENZA VACCINES; MADIN DARBY CANINE KIDNEY CELLS; MOLECULAR SEQUENCE DATA; MUTATION; SEQUENCE ANALYSIS, DNA; VERO CELLS; VIRAL NONSTRUCTURAL PROTEINS; VIRUS REPLICATION;

INFLUENZA A VIRUS; ORTHOMYXOVIRIDAE;

EID: 84869118918     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.01725-12     Document Type: Article

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