Genomic and protein structural maps of adaptive evolution of human influenza a virus to increased virulence in the mouse

PLoS ONE

Volumn 6, Issue 6, 2011, Pages

  Ping, Jihui ^a   Keleta, Liya ^a   Forbes, Nicole E ^a   Dankar, Samar ^a   Stecho, William ^a   Tyler, Shaun ^b   Zhou, Yan ^a,c   Babiuk, Lorne ^a,c   Weingartl, Hana ^a,d   Halpin, Rebecca A ^e   Boyne, Alex ^e   Bera, Jayati ^e   Hostetler, Jessicah ^e   Fedorova, Nadia B ^e   Proudfoot, Katie ^e   Katzel, Dan A ^e   Stockwell, Tim B ^e   Ghedin, Elodie ^e,f   Spiro, David J ^e   Brown, Earl G ^a  

^a UNIVERSITY OF OTTAWA   (Canada)

^b Public Health Agency of Canada   (Canada)

^c UNIVERSITY OF SASKATCHEWAN   (Canada)

^d CANADIAN FOOD INSPECTION AGENCY   (Canada)

^e J CRAIG VENTER INSTITUTE   (United States)

^f UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INFLUENZA VIRUS HEMAGGLUTININ; NONSTRUCTURAL PROTEIN 1; RNA POLYMERASE; VIRUS NUCLEOPROTEIN; VIRUS SIALIDASE; VIRUS PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; EVOLUTION; GENE EXPRESSION; GENE MUTATION; GENETIC EPISTASIS; HUMAN; HUMAN CELL; INFLUENZA; INFLUENZA VIRUS A; MOUSE; NATURAL SELECTION; NONHUMAN; PROTEIN STRUCTURE; VIRUS CELL INTERACTION; VIRUS GENE; VIRUS GENOME; VIRUS REPLICATION; VIRUS VIRULENCE; ANIMAL; CELL LINE; DOG; GENETICS; METABOLISM; VIRULENCE;

INFLUENZA A VIRUS;

ANIMALS; CELL LINE; DOGS; GENOME, VIRAL; HUMANS; INFLUENZA A VIRUS; MICE; VIRAL PROTEINS; VIRULENCE;

EID: 79959725144     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0021740     Document Type: Article

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