Role of Bcl-2 in tumour cell survival and implications for pharmacotherapy

Journal of Pharmacy and Pharmacology

Volumn 64, Issue 12, 2012, Pages 1695-1702

  Tomek, Mary ^a   Akiyama, Toru ^b   Dass, Crispin R ^a  

^a VICTORIA UNIVERSITY   (Australia)

^b JICHI MEDICAL UNIVERSITY   (Japan)

Author keywords

apoptosis; Bcl 2; cancer; cell survival; FKBP 38; Nur 77

Indexed keywords

4 [4 (4' CHLORO 2 BIPHENYLYLMETHYL) 1 PIPERAZINYL] N [4 [3 DIMETHYLAMINO 1 (PHENYLTHIOMETHYL)PROPYLAMINO] 3 NITROBENZENESULFONYL]BENZAMIDE; BH3 PROTEIN; FK 506 BINDING PROTEIN; FK 506 BINDING PROTEIN 38; NUCLEAR RECEPTOR NUR77; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN MCL 1; TUMOR NECROSIS FACTOR RECEPTOR; UNCLASSIFIED DRUG;

APOPTOSIS; AUTOPHAGY; CANCER CHEMOTHERAPY; CANCER PATIENT; CANCER RESEARCH; CARCINOGENESIS; CELL SURVIVAL; DEMENTIA; DRUG MECHANISM; ENDOPLASMIC RETICULUM STRESS; HUMAN; MITOCHONDRION; MITOSIS; MOLECULAR INTERACTION; NONHUMAN; PHOTODYNAMIC THERAPY; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; REVIEW; SIGNAL TRANSDUCTION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BH3 INTERACTING DOMAIN DEATH AGONIST PROTEIN; CELL SURVIVAL; HUMANS; MITOSIS; NEOPLASMS; PROTO-ONCOGENE PROTEINS C-BCL-2; TACROLIMUS BINDING PROTEINS; WISKOTT-ALDRICH SYNDROME PROTEIN FAMILY;

EID: 84869093332     PISSN: 00223573     EISSN: 20427158     Source Type: Journal    
DOI: 10.1111/j.2042-7158.2012.01526.x     Document Type: Review

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