The extrinsic and intrinsic apoptotic pathways are differentially affected by temperature upstream of mitochondrial damage

Apoptosis

Volumn 11, Issue 8, 2006, Pages 1339-1347

  López Hernández, Francisco J ^a,b   Ortiz, María A ^a   Piedrafita, F Javier ^a  

^a SIDNEY KIMMEL CANCER CENTER   (United States)

^b HOSPITAL UNIVERSITARIO DE SALAMANCA   (Spain)

Author keywords

Apoptosis; Extrinsic pathway; Fas; Intrinsic pathway; Retinoid related molecules; Temperature

Indexed keywords

CASPASE 3; CYTOCHROME C; FAS ANTIBODY; PHOSPHATIDYLSERINE; RECOMBINANT ENZYME; RETINOID;

APOPTOSIS; ARTICLE; ENZYME ACTIVATION; ENZYME PURIFICATION; HUMAN; HUMAN CELL; HYPOTHERMIA; LEUKEMIA CELL LINE; MITOCHONDRION; PRIORITY JOURNAL; PROTEIN SECRETION; ROOM TEMPERATURE; TEMPERATURE; ULTRAVIOLET RADIATION;

ANTIGENS, CD95; APOPTOSIS; CASPASE 3; CASPASE 8; CASPASE 9; CYTOCHROMES C; ENZYME ACTIVATION; HUMANS; JURKAT CELLS; MITOCHONDRIA; PHOSPHATIDYLSERINES; TEMPERATURE; ULTRAVIOLET RAYS;

EID: 33745812449     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-006-7689-z     Document Type: Article

References (59)

1. Reed JC (1999) Mechanisms of apoptosis avoidance in cancer. Curr Opin Oncol 11:68-75
2. Green DR, Evan GI (2002) A matter of life and death. Cancer Cell 1:19-30
3. Kaina B (2003) DNA damage-triggered apoptosis: Critical role of DNA repair, double-strand breaks, cell proliferation and signaling. Biochem Pharmacol 66:1547-1554
4. Gourlay CW, Ayscough KR (2005) The actin cytoskeleton: A key regulator of apoptosis and ageing? Nat Rev Mol Cell Biol 6: 583-589
5. Mollinedo F, Gajate C (2003) Microtubules, microtubule-interfering agents and apoptosis. Apoptosis 8:413-450
6. Ferri KF, Kroemer G (2001) Organelle-specific initiation of cell death pathways. Nat Cell Biol 3:E255-E263
7. Machamer CE (2003) Golgi disassembly in apoptosis: Cause or effect? Trends Cell Biol 13:279-281
8. Hicks SW, Machamer CE (2005) Golgi structure in stress sensing and apoptosis. Biochim Biophys Acta 1744:406-414
9. Breckenridge DG, Germain M, Mathai JP, Nguyen M, Shore GC (2003) Regulation of apoptosis by endoplasmic reticulum pathways. Oncogene 22:8608-8618
10. Szabadkai G, Rizzuto R (2004) Participation of endoplasmic reticulum and mitochondrial calcium handling in apoptosis: More than just neighborhood? FEBS Lett 567:111-115
11. Wang X (2001) The expanding role of mitochondria in apoptosis. Genes Dev 15:2922-2933
12. Susin SA, Lorenzo HK, Zamzami N, et al (1999) Molecular characterization of mitochondrial apoptosis-inducing factor. Nature 397:441-446
13. Suzuki Y, Imai Y, Nakayama H, Takahashi K, Takio K, Takahashi R (2001) A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death. Mol Cell 8:613-621
14. Du C, Fang M, Li Y, Li L, Wang X (2000) Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition. Cell 102:33-42
15. Verhagen AM, Ekert PG, Pakusch M, et al (2000) Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing LAP proteins. Cell 102:43-53
16. Li LY, Luo X, Wang X (2001) Endonuclease G is an apoptotic DNase when released from mitochondria. Nature 412:95-99
17. Budihardjo I, Oliver H, Lutter M, Luo X, Wang X (1999) Biochemical pathways of caspase activation during apoptosis. Annu Rev Cell Dev Biol 15:269-290
18. Nicholson DW (1999) Caspase structure, proteolytic substrates, and function during apoptotic cell death. Cell Death Differ 6:1028-1042
19. Chang HY, Yang X (2000) Proteases for cell suicide: Functions and regulation of caspases. Microbiol Mol Biol Rev 64:821-846
20. Hao Z, Duncan GS, Chang CC, et al (2005) Specific ablation of the apoptotic functions of cytochrome c reveals a differential requirement for cytochrome c and Apaf-1 in apoptosis. Cell 121:579-591
21. Ortiz MA, Bayon Y, Lopez-Hernandez FJ, Piedrafita FJ (2002) Retinoids in combination therapies for the treatment of cancer: Mechanisms and perspectives. Drug Resist Updat 5:162-175
22. Pfahl M, Piedrafita FJ (2003) Retinoid targets for apoptosis induction. Oncogene 22:9058-9062
23. Nagata S (1999) Fas ligand-induced apoptosis. Annu Rev Genet 33:29-55
24. Budd RC (2002) Death receptors couple to both cell proliferation and apoptosis. J Clin Invest 109:437-441
25. Walczak H, Sprick MR (2001) Biochemistry and function of the DISC. Trends Biochem Sci 26:452-453
26. Korsmeyer SJ, Wei MC, Saito M, Weiler S, Oh KJ, Schlesinger PH (2000) Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c. Cell Death Differ 7:1166-1173
27. Esposti MD (2002) The roles of bid. Apoptosis 7:433-440
28. Scoltock AB, Cidlowski JA (2004) Activation of intrinsic and extrinsic pathways in apoptotic signaling during UV-C-induced death of Jurkat cells: The role of caspase inhibition. Exp Cell Res 297:212-223
29. Takasawa R, Nakamura H, Mori T, Tanuma S (2005) Differential apoptotic pathways in human keratinocyte HaCaT cells exposed to UVB and UVC. Apoptosis 10:1121-1130
30. Mayr M, Li C, Zou Y, Huemer U, Hu Y, Xu Q (2000) Biomechanical stress-induced apoptosis in vein grafts involves p38 mitogen-activated protein kinases. FASEB J 14:261-270
31. Lagadic-Gossmann D, Huc L, Lecureur V (2004) Alterations of intracellular pH homeostasis in apoptosis: Origins and roles. Cell Death Differ 11:953-961
32. Bettaieb A, Averill-Bates DA (2005) Thermotolerance induced at a mild temperature of 40 degrees C protects cells against heat shock-induced apoptosis. J Cell Physiol 205:47-57
33. Shimura M, Ishizaka Y, Yuo A, et al (1997) Characterization of room temperature induced apoptosis in HL-60. FEBS Lett 417:379-384
34. Shimura M, Okuma E, Yuo A, et al (1998) Room temperature-induced apoptosis of Jurkat cells sensitive to both caspase-1 and caspase-3 inhibitors. Cancer Lett 132:7-16
35. Shimura M, Osawa Y, Yuo A, Hatake K, Takaku F, Ishizaka Y (2000) Oxidative stress as a necessary factor in room temperature-induced apoptosis of HL-60 cells. J Leukoc Biol 68:87-96
36. Lopez-Hernandez FJ, Ortiz MA, Bayon Y, Piedrafita FJ (2004) Retinoid-related molecules require caspase 9 for the effective release of Smac and the rapid induction of apoptosis. Cell Death Differ 11:154-164
37. Ortiz MA, Lopez-Hernandez FJ, Bayon Y, Pfahl M, Piedrafita FJ (2001) Retinoid-related molecules induce cytochrome c release and apoptosis through activation of c-Jun NH(2)-terminal kinase/p38 mitogen-activated protein kinases. Cancer Res 61:8504-8512
38. Bayon Y, Ortiz MA, Lopez-Hernandez FJ, et al (2003) Inhibition of IκB kinase by a new class of retinoid-related anticancer agents that induce apoptosis. Mol Cell Biol 23:1061-1074
39. Lopez-Hernandez FJ, Ortiz MA, Bayon Y, Piedrafita FJ (2003) Z-FA-fmk inhibits effector caspases but not initiator caspases 8 and 10, and demonstrates that novel anticancer retinoid-related molecules induce apoptosis via the intrinsic pathway. Molecular Cancer Therapeutics 2:255-263
40. Inamasu J, Suga S, Sato S, et al (2000) Postischemic hypothermia attenuates apoptotic cell death in transient focal ischemia in rats. Acta Neurochir Suppl 76:525-527
41. Fukuda H, Tomimatsu T, Watanabe N, et al (2001) Post-ischemic hypothermia blocks caspase-3 activation in the newborn rat brain after hypoxia-ischemia. Brain Res 910:187-191
42. Zhu C, Wang X, Cheng X, et al (2004) Post-ischemic hypothermia-induced tissue protection and diminished apoptosis after neonatal cerebral hypoxia-ischemia. Brain Res 996:67-75
43. Ohmura A, Nakajima W, Ishida A, et al (2005) Prolonged hypothermia protects neonatal rat brain against hypoxic-ischemia by reducing both apoptosis and necrosis. Brain Dev 27:517-526
44. Zhao H, Shimohata T, Wang JQ, et al (2005) Akt contributes to neuroprotection by hypothermia against cerebral ischemia in rats. J Neurosci 25:9794-9806
45. Sakurai T, Itoh K, Liu Y, et al (2005) Low temperature protects mammalian cells from apoptosis initiated by various stimuli in vitro. Exp Cell Res 309:264-272
46. Fu T, Blei AT, Takamura N, et al (2004) Hypothermia inhibits Fas-mediated apoptosis of primary mouse hepatocytes in culture. Cell Transplant 13:667-676
47. Bergman M, Bessler H, Salman H, Djaldetti M (2003) Relationship between temperature and apoptosis of human peripheral blood mononuclear cells. Int J Hematol 77:351-353
48. Barnhart BC, Alappat EC, Peter ME (2003) The CD95 type I/type II model. Semin Immunol 15:185-193
49. Scaffidi C, Schmitz I, Zha J, Korsmeyer SJ, Krammer PH, Peter ME (1999) Differential modulation of apoptosis sensitivity in CD95 type I and type II cells. J Biol Chem 274:22532-22538
50. Schmitz I, Walczak H, Krammer PH, Peter ME (1999) Differences between CD95 type I and II cells detected with the CD95 ligand. Cell Death Differ 6:821-822
51. Yin XM, Wang K, Gross A, et al (1999) Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis. Nature 400:886-891
52. Huang DC, Tschopp J, Strasser A (2000) Bcl-2 does not inhibit cell death induced by the physiological Fas ligand: Implications for the existence of type I and type II cells. Cell Death Differ 7:754-755
53. Knight MJ, Riffkin CD, Ekert PG, Ashley DM, Hawkins CJ (2004) Caspase-8 levels affect necessity for mitochondrial amplification in death ligand-induced glioma cell apoptosis. Mol Carcinog 39:173-182
54. Yenari MA, Iwayama S, Cheng D, et al (2002) Mild hypothermia attenuates cytochrome c release but does not alter Bcl-2 expression or caspase activation after experimental stroke. J Cereb.Blood Flow Metab 22:29-38
55. Ning XH, Chen SH, Xu CS, et al (2002) Hypothermic protection of the ischemic heart via alterations in apoptotic pathways as assessed by gene array analysis. J Appl Physiol 92:2200-2207
56. Eberspacher E, Werner C, Engelhard K, et al (2005) Long-term effects of hypothermia on neuronal cell death and the concentration of apoptotic proteins after incomplete cerebral ischemia and reperfusion in rats. Acta Anaesthesiol Scand 49:477-487
57. Xu L, Yenari MA, Steinberg GK, Giffard RG (2002) Mild hypothermia reduces apoptosis of mouse neurons in vitro early in the cascade. J Cereb Blood Flow Metab 22:21-28
58. Marchetti P, Zamzami N, Joseph B, et al (1999) The novel retinoid 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphtalene carboxylic acid can trigger apoptosis through a mitochondrial pathway independent of the nucleus. Cancer Res 59:6257-6266
59. Mologni L, Ponzanelli I, Bresciani F, et al (1999) The novel synthetic retinoid 6-[3-adamantyl-4-hydroxyphenyl]-2- naphthalene carboxylic acid (CD437) causes apoptosis in acute promyelocytic leukemia cells through rapid activation of caspases. Blood 93:1045-1061