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Volumn 31, Issue 44, 2012, Pages 4725-4731

Mitochondrial respiratory uncoupling promotes keratinocyte differentiation and blocks skin carcinogenesis

Author keywords

carcinogenesis; differentiation; mitochondria; skin; uncoupling proteins

Indexed keywords

BROXURIDINE; CYTOKERATIN 5; UNCOUPLING PROTEIN 1; UNCOUPLING PROTEIN 2; UNCOUPLING PROTEIN 3;

EID: 84869083044     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2011.630     Document Type: Article
Times cited : (16)

References (42)
  • 1
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell 2011; 144: 646-674.
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 2
    • 12444279265 scopus 로고
    • On the origin of cancer cells
    • Warburg O. On the origin of cancer cells. Science 1956; 123: 309-314.
    • (1956) Science , vol.123 , pp. 309-314
    • Warburg, O.1
  • 4
    • 0034006016 scopus 로고    scopus 로고
    • HIF-1: Mediator of physiological and pathophysiological responses to hypoxia
    • Semenza GL. HIF-1: mediator of physiological and pathophysiological responses to hypoxia. J Appl Physiol 2000; 88: 1474-1480. (Pubitemid 30217451)
    • (2000) Journal of Applied Physiology , vol.88 , Issue.4 , pp. 1474-1480
    • Semenza, G.L.1
  • 5
    • 61849161672 scopus 로고    scopus 로고
    • Oct1 loss of function induces a coordinate metabolic shift that opposes tumorigenicity
    • Shakya A, Cooksey R, Cox JE, Wang V, McClain DA, Tantin D. Oct1 loss of function induces a coordinate metabolic shift that opposes tumorigenicity. Nat Cell Biol 2009; 11: 320-327.
    • (2009) Nat Cell Biol , vol.11 , pp. 320-327
    • Shakya, A.1    Cooksey, R.2    Cox, J.E.3    Wang, V.4    McClain, D.A.5    Tantin, D.6
  • 9
    • 0021717130 scopus 로고
    • Calcium-induced reorganization of desmosomal components in cultured human keratinocytes
    • DOI 10.1083/jcb.99.6.2211
    • Watt FM, Mattey DL, Garrod DR. Calcium-induced reorganization of desmosomal components in cultured human keratinocytes. J Cell Biol 1984; 99: 2211-2215. (Pubitemid 15181885)
    • (1984) Journal of Cell Biology , vol.99 , Issue.6 , pp. 2211-2215
    • Watt, F.M.1    Mattey, D.L.2    Garrod, D.R.3
  • 10
    • 34249789291 scopus 로고    scopus 로고
    • Squamous cell carcinoma induced by ultraviolet radiation originates from cells of the hair follicle in mice
    • DOI 10.1111/j.1600-0625.2007.00551.x
    • Faurschou A, Haedersdal M, Poulsen T, Wulf HC. Squamous cell carcinoma induced by ultraviolet radiation originates from cells of the hair follicle in mice. Exp Dermatol 2007; 16: 485-489. (Pubitemid 46845391)
    • (2007) Experimental Dermatology , vol.16 , Issue.6 , pp. 485-489
    • Faurschou, A.1    Haedersdal, M.2    Poulsen, T.3    Wulf, H.C.4
  • 11
    • 0034650889 scopus 로고    scopus 로고
    • Evidence that the epidermal targets of carcinogen action are found in the interfollicular epidermis or infundibulum as well as in the hair follicles
    • Morris RJ, Tryson KA, Wu KQ. Evidence that the epidermal targets of carcinogen action are found in the interfollicular epidermis of infundibulum as well as in the hair follicles. Cancer Res 2000; 60: 226-229. (Pubitemid 30070738)
    • (2000) Cancer Research , vol.60 , Issue.2 , pp. 226-229
    • Morris, R.J.1    Tryson, K.A.2    Wu, K.Q.3
  • 12
    • 0025313294 scopus 로고
    • Label-retaining cells reside in the bulge area of pilosebaceous unit: Implications for follicular stem cells, hair cycle, and skin carcinogenesis
    • Cotsarelis G, Sun TT, Lavker RM. Label-retaining cells reside in the bulge area of pilosebaceous unit: Implications for follicular stem cells, hair cycle, and skin carcinogenesis. Cell 1990; 61: 1329-1337.
    • (1990) Cell , vol.61 , pp. 1329-1337
    • Cotsarelis, G.1    Sun, T.T.2    Lavker, R.M.3
  • 14
    • 16644376120 scopus 로고    scopus 로고
    • Method for the harvest and assay of in vitro clonogenic keratinocytes stem cells from mice
    • Wu WY, Morris RJ. Method for the harvest and assay of in vitro clonogenic keratinocytes stem cells from mice. Methods Mol Biol 2005; 289: 79-86.
    • (2005) Methods Mol Biol , vol.289 , pp. 79-86
    • Wu, W.Y.1    Morris, R.J.2
  • 15
    • 23244452354 scopus 로고    scopus 로고
    • Developmental biology: Stem cell depletion through epidermal deletion of Rac1
    • DOI 10.1126/science.1113579
    • Benitah SA, Frye M, Glogauer M, Watt FM. Stem cell depletion through epidermal deletion of rac1. Science 2005; 309: 933-935. (Pubitemid 41099929)
    • (2005) Science , vol.309 , Issue.5736 , pp. 933-935
    • Benitah, S.A.1    Frye, M.2    Glogauer, M.3    Watt, F.M.4
  • 16
    • 28644451449 scopus 로고    scopus 로고
    • Stem cells in the hair follicle bulge contribute to wound repair but not to homeostasis of the epidermis
    • DOI 10.1038/nm1328
    • Ito M, Liu Y, Yang Z, Nguyen J, Liang F, Morris RJ et al. Stem cells in the hair follicle bulge contribute to wound repair but not to homeostasis of the epidermis. Nat Med 2005; 11: 1351-1354. (Pubitemid 41752917)
    • (2005) Nature Medicine , vol.11 , Issue.12 , pp. 1351-1354
    • Ito, M.1    Liu, Y.2    Yang, Z.3    Nguyen, J.4    Liang, F.5    Morris, R.J.6    Cotsarelis, G.7
  • 20
    • 0033767445 scopus 로고    scopus 로고
    • Mutations in sdhc cause autosomal dominant paraganglioma, type 3
    • Niemann S, Muller U. Mutations in sdhc cause autosomal dominant paraganglioma, type 3. Nat Genet 2000; 26: 268-270.
    • (2000) Nat Genet , vol.26 , pp. 268-270
    • Niemann, S.1    Muller, U.2
  • 23
    • 34247614521 scopus 로고    scopus 로고
    • HIF-1 inhibits mitochondrial biogenesis and cellular respiration in VHL-deficient renal cell carcinoma by repression of C-MYC activity
    • DOI 10.1016/j.ccr.2007.04.001, PII S1535610807001158
    • Zhang H, Gao P, Fukuda R, Kumar G, Krishnamachary B, Zeller KI et al. HIF-1 inhibits mitochondrial biogenesis and cellular respiration in vhl-deficient renal cell carcinoma by repression of c-myc activity. Cancer Cell 2007; 11: 407-420. (Pubitemid 46670080)
    • (2007) Cancer Cell , vol.11 , Issue.5 , pp. 407-420
    • Zhang, H.1    Gao, P.2    Fukuda, R.3    Kumar, G.4    Krishnamachary, B.5    Zeller, K.I.6    Dang, ChiV.7    Semenza, G.L.8
  • 24
    • 79956265753 scopus 로고    scopus 로고
    • Negative regulation of ucp2 by TGF-beta signaling characterizes low and intermediategrade primary breast cancer
    • Sayeed A, Meng Z, Luciani G, Chen LC, Bennington JL, Dairkee SH. Negative regulation of ucp2 by TGF-beta signaling characterizes low and intermediategrade primary breast cancer. Cell Death Dis 2010; 1: e53.
    • (2010) Cell Death Dis , vol.1
    • Sayeed, A.1    Meng, Z.2    Luciani, G.3    Chen, L.C.4    Bennington, J.L.5    Dairkee, S.H.6
  • 25
    • 42349088894 scopus 로고    scopus 로고
    • The mitochondrial uncoupling protein-2 promotes chemoresistance in cancer cells
    • DOI 10.1158/0008-5472.CAN-08-0053
    • Derdak Z, Mark NM, Beldi G, Robson SC, Wands JR, Baffy G. The mitochondrial uncoupling protein-2 promotes chemoresistance in cancer cells. Cancer Res 2008; 68: 2813-2819. (Pubitemid 351556280)
    • (2008) Cancer Research , vol.68 , Issue.8 , pp. 2813-2819
    • Derdak, Z.1    Mark, N.M.2    Beldi, G.3    Robson, S.C.4    Wands, J.R.5    Baffy, G.6
  • 26
    • 33646188854 scopus 로고    scopus 로고
    • Enhanced colon tumor induction in uncoupling protein-2 deficient mice is associated with nf-kappab activation and oxidative stress
    • Derdak Z, Fulop P, Sabo E, Tavares R, Berthiaume EP, Resnick MB et al. Enhanced colon tumor induction in uncoupling protein-2 deficient mice is associated with nf-kappab activation and oxidative stress. Carcinogenesis 2006; 27: 956-961.
    • (2006) Carcinogenesis , vol.27 , pp. 956-961
    • Derdak, Z.1    Fulop, P.2    Sabo, E.3    Tavares, R.4    Berthiaume, E.P.5    Resnick, M.B.6
  • 29
    • 0032544720 scopus 로고    scopus 로고
    • 2 by mitochondria in the resting state
    • DOI 10.1016/S0014-5793(98)01073-4, PII S0014579398010734
    • Korshunov SS, Korkina OV, Ruuge EK, Skulachev VP, Starkov AA. Fatty acids as natural uncouplers preventing generation of O2.-and H2O2 by mitochondria in the resting state. FEBS Lett 1998; 435: 215-218. (Pubitemid 28435003)
    • (1998) FEBS Letters , vol.435 , Issue.2-3 , pp. 215-218
    • Korshunov, S.S.1    Korkina, O.V.2    Ruuge, E.K.3    Skulachev, V.P.4    Starkov, A.A.5
  • 35
    • 0018721266 scopus 로고
    • Presence in human epidermal cells of a soluble protein precursor of the cross-linked envelope: Activation of the cross-linking by calcium ions
    • Rice RH, Green H. Presence in human epidermal cells of a soluble protein precursor of the cross-linked envelope: activation of the cross-linking by calcium ions. Cell 1979; 18: 681-694. (Pubitemid 10216994)
    • (1979) Cell , vol.18 , Issue.3 , pp. 681-694
    • Rice, R.H.1    Green, H.2
  • 37
    • 79151485570 scopus 로고    scopus 로고
    • Mitochondrial trafficking and the provision of energy and calcium buffering at excitatory synapses
    • MacAskill AF, Atkin TA, Kittler JT. Mitochondrial trafficking and the provision of energy and calcium buffering at excitatory synapses. Eur J Neurosci 2010; 32: 231-240.
    • (2010) Eur J Neurosci , vol.32 , pp. 231-240
    • MacAskill, A.F.1    Atkin, T.A.2    Kittler, J.T.3
  • 39
    • 0021451717 scopus 로고
    • Proton and calcium circuits across the mitochondrial inner membrane
    • Nicholls DG, Snelling R, Rial E. Proton and calcium circuits across the mitochondrial inner membrane. Biochem Soc Trans 1984; 12: 388-390.
    • (1984) Biochem Soc Trans , vol.12 , pp. 388-390
    • Nicholls, D.G.1    Snelling, R.2    Rial, E.3
  • 40
    • 27744601467 scopus 로고    scopus 로고
    • Induction of apoptosis-like mitochondrial impairment triggers antioxidant and bcl-2-dependent keratinocyte differentiation
    • Tamiji S, Beauvillain JC, Mortier L, Jouy N, Tual M, Delaporte E et al. Induction of apoptosis-like mitochondrial impairment triggers antioxidant and bcl-2-dependent keratinocyte differentiation. J Invest Dermatol 2005; 125: 647-658.
    • (2005) J Invest Dermatol , vol.125 , pp. 647-658
    • Tamiji, S.1    Beauvillain, J.C.2    Mortier, L.3    Jouy, N.4    Tual, M.5    Delaporte, E.6
  • 42
    • 75749146169 scopus 로고    scopus 로고
    • Coexistence of quiescent and active adult stem cells in mammals
    • Li L, Clevers H. Coexistence of quiescent and active adult stem cells in mammals. Science 2010; 327: 542-545.
    • (2010) Science , vol.327 , pp. 542-545
    • Li, L.1    Clevers, H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.