Are synapses targets of nanoparticles?

Biochemical Society Transactions

Volumn 38, Issue 2, 2010, Pages 536-538

  Fedorovich, Sergei V ^a   Alekseenko, Alexandra V ^a,b   Waseem, Tatyana V ^a  

^a INSTITUTE OF PHOTOBIOLOGY   (Belarus)

^b BELARUSIAN MEDICAL ACADEMY OF POSTGRADUATE EDUCATION   (Belarus)

Author keywords

Ferritin; Free radical; Glutamate release; Glutamate uptake; Nanoparticle; Synaptosome

Indexed keywords

DICHLOROFLUORESCEIN; FERRITIN; FREE RADICAL; GLUTAMIC ACID; NANOPARTICLE; REACTIVE OXYGEN METABOLITE;

BRAIN INJURY; MICROGLIA; NERVE CELL; NERVE DEGENERATION; NERVE ENDING; NERVE INJURY; NEUROTRANSMISSION; NEUROTRANSMITTER RELEASE; NEUROTRANSMITTER UPTAKE; PRIORITY JOURNAL; REVIEW; SYNAPSE; ANIMAL; BRAIN DISEASE; CHEMISTRY; DRUG DELIVERY SYSTEM; DRUG EFFECT; EVALUATION; HUMAN; METABOLISM; METHODOLOGY; PATHOLOGY; PHYSIOLOGY;

ANIMALS; BRAIN DISEASES; DRUG DELIVERY SYSTEMS; FERRITINS; HUMANS; NANOPARTICLES; SYNAPSES;

EID: 77953281691     PISSN: 03005127     EISSN: 14708752     Source Type: Journal    
DOI: 10.1042/BST0380536     Document Type: Review

References (34)

1. Silva, G.A. (2006) Neuroscience nanotechnology: progress, opportunities and challenges. Nat. Rev. Neurosci. 7, 65-74
2. Jain, K.K. (2007) Applications of nanobiotechnology in clinical diagnostics. Clin. Chem. 53, 2002-2009
3. Medina, C., Santos-Martinez, M.J., Radomski, A., Corrigan, O.I. and Radomski, M.V. (2007) Nanoparticles: pharmacological and toxicological significance. Br. J. Pharmacol. 150, 552-558
4. Suh, W.H., Suslick, K.S., Stucky, G.D. and Suh, Y.-H. (2009) Nanotechnology, nanotoxicology, and neuroscience. Prog. Neurobiol. 87, 133-170
5. Oberd̈orster, G., Oberdörster, E. and Oberdörster, J. (2005) Nanotoxicology: an emerging discipline evolving from studies of ultrafine particles. Environ. Health Perspect. 113, 823-839
6. Nel, A., Xia, T., Madler, L. and Li, N. (2006) Toxic potential of materials at the nanolevel. Science 311, 622-627
7. Gianutsos, G., Morrow, G.R. and Morris, J.B. (1997) Accumulation of manganese in rat brain following intranasal administration. Fundam. Appl. Toxicol. 37, 102-105
8. Weiss, C.K., Kohnle M.-V., Landfester, K., Hauk, T., Fisher, D., Schmitz-Wienke, J., Mailänder and V., Mailänder (2008) The first step into the brain: uptake of NIO-PBCA nanoparticles by endothelial cells in vitro and in vivo, and direct evidence for their blood-brain barrier permeation. ChemMedChem 3, 1395-1403
9. Wang, B., Feng, W., Zhu, M., Wang, Y., Wang, M., Gu, Y., Ouyang, H., Wang, H., Li, M., Zhao, Y., Chai, Z. and Wang, H. (2009) Neurotoxicity of low-dose repeatedly intranasal installation of nano- and submicron-sized ferric oxide particles in mice. J. Nanoparticle Res. 11, 41-53
10. Calderon-Garciduenas, L., Azzarelli, B., Acuna, H., Garcia, R., Gambling, T.M., Osnaya, N., Monroy, S., Del Tizapantzi, M.R., Carson, J.L., Villareal-Calderon, A. and Rewcastle, B. (2002) Air pollution and brain damage. Toxicol. Pathol. 30, 373-389
11. Block, M.L., Wu, X., Pei, Z., Li, G., Wang, T., Qin, L., Wilson, B., Yang, J., Hong, J.S. and Veronesi, B. (2004) Nanometer size diesel exhaust particles are selectively toxic to dopaminergic neurons: the role of microglia, phagocytosis, and NADPH oxidase. FASEB J. 18, 1618-1620 (Pubitemid 39561652)
12. Block, M.L., Zecca, L. and Hong, J.-S. (2007) Microglia-mediated neurotoxicity: uncovering the molecular mechanisms. Nat. Rev. Neurosci. 8, 57-69
13. Tang, M., Xing, T., Zeng, J., Wang, H., Li, C., Yin, S., Yan, D., Deng, H., Liu, J., Wang, M., Chen, J. and Ruan, D.-Y. (2008) Unmodified CdSe quantum dots induce elevation of cytoplasmic levels and impairment of functional properties of sodium channels in rat primary cultured hippocampal neurons. Environ. Health Perspect. 116, 915-922
14. Von Bohlen und Halbach, O., Schober, A. and Krieglstein, K. (2004) Genes, proteins, and neurotoxins involved in Parkinson's disease. Prog. Neurobiol. 73, 151-177
15. Masters, C.L., Cappai, R., Barnham, K.J. and Villemagne, V.L. (2006) Molecular mechanisms for Alzheimer's disease: implications for neuroimaging and theurapeutics. J. Neurochem. 97, 1700-1725 (Pubitemid 43873662)
16. Lipton, P. (1999) Ischemic cell death in brain neurons. Physiol. Rev. 79, 1431-1568
17. Dobson, J. (2001) Nanoscale biogenic iron oxides and neurodegenerative disease. FEBS Lett. 496, 1-5
18. Wu, W.-H., Sun, X., Yu, Y.-P., Hu, J., Zhao, L., Liu, L., Zhao, Y.-F. and Li, Y.-M. (2008) TiO2 nanoparticles promote β-amyloid fibrillation in vitro. Biochem. Biophys. Res. Commun. 373, 315-318
19. Zhao, J., Xu, L., Zhang, T., Ren, G. and Yang, Z. (2009) Influences of nanoparticle zinc oxide on acutely isolated rat hippocampal CA3 pyramidal neurons. Neurotoxicology 30, 220-230
20. Zhang, Q., Cao, Y.-Q. and Tsien, R.W. (2007) Quantum dots provide an optical signal specific to full collapse fusion of synaptic vesicles. Proc. Natl. Acad. Sci. U.S.A. 104, 17843-17848
21. Schrimpf, S.P., Meskenaite, V., Brunner, E., Ruthishauser, D., Walther, P., Eng, J., Aebersold, R. and Sonderegger, P. (2005) Proteomic analysis of synaptosomes using isotope-coded affinity tags and mass spectrometry. Proteomics 5, 2631-2641 (Pubitemid 40966480)
22. Waseem, T.V., Kolos, V.A., Lapatsina, L.P. and Fedorovich, S.V. (2007) Hypertonic shrinking but not hypotonic swelling increases sodium concentration in rat brain synaptosomes. Brain Res. Bull. 73, 135-142
23. Waseem, T.V., Konev, S.V. and Fedorovich, S.V. (2004) Influence of hypotonic shock on glutamate and GABA uptake in rat brain synaptosomes. Neurochem. Res. 29, 1653-1658
24. Waseem, T.V., Rakovich, A.A., Lavrukevich, T.V., Konev, S.V. and Fedorovich, S.V. (2005) Calcium regulates the mode of exocytosis induced by hypotonic shock in isolated neuronal presynaptic endings. Neurochem. Int. 46, 235-242
25. Gupta, A.K., Naregalkar, R.R., Vaidya, V.D. and Gupta, M. (2007) Recent advances on surface engineering of magnetic iron oxide nanoparticles and their biomedical applications. Nanomedicine 2, 23-39
26. Double, K.L., Maywald, M., Schmittel, M., Riederer, P. and Gerlach, M. (1998) In vitro studies of ferritin iron release and neurotoxicity. J. Neurochem. 70, 2492-2499
27. Halliwell, B. (2006) Oxidative stress and neurodegeneration: where are we now? J. Neurochem. 97, 1634-1658 (Pubitemid 43873658)
28. Zecca, L., Youdim, M.B.H., Riederer, P., Connor, J.R. and Crichton, R.R. (2004) Iron, brain ageing and neurodegenerative disorders. Nat. Rev. Neurosci. 5, 863-873
29. Alekseenko, A.V., Waseem, T.V. and Fedorovich, S.V. (2008) Ferritin, a protein containing iron nanoparticles, induces reactive oxygen species formation and inhibits glutamate uptake in rat brain synaptosomes. Brain Res. 1241, 193-200
30. Rothstein, J.D., Jin, L., Dykes-Hoberg, M. and Kuncl, R.W. (1993) Chronic inhibition of glutamate uptake produces a model of slow neurotoxicity. Proc. Natl. Acad. Sci. U.S.A. 90, 6591-6595
31. Trotti, D., Aoki, M., Pasinelli, P., Berger, U.V., Danbolt, N.C., Brown, Jr, R.H. and Hediger, M.A. (2001) Amyotrophic lateral sclerosis-linked glutamate transporter mutant has impaired glutamate clearance capacity. J. Biol. Chem. 276, 576-582
32. Tretter, L. and Adam-Vizi, V. (2007) Uncoupling is without an effect on the production of reactive oxygen species by in situ synaptic mitochondria. J. Neurochem. 103, 1864-1871
33. Giniatullin, A.R., Darios, F., Shakirzyanova, A., Davletov, B. and Giniatullin, R. (2006) SNAP25 is a pre-synaptic target for the depressant action of reactive oxygen species on transmitter release. J. Neurochem. 98, 1789-1797 (Pubitemid 44298245)
34. Keating, D.I. (2008) Mitochondrial dysfunction, oxidative stress, regulation of exocytosis and their relevance to neurodegenerative diseases. J. Neurochem. 104, 298-305