Induction of chronic inflammation in mice treated with titanium dioxide nanoparticles by intratracheal instillation

Toxicology

Volumn 260, Issue 1-3, 2009, Pages 37-46

  Park, Eun Jung ^a   Yoon, Junheon ^b   Choi, Kyunghee ^b   Yi, Jongheop ^c   Park, Kwangsik ^a  

^a Dongduk Women's University   (South Korea)

^b National Institute of Environmental Research   (South Korea)

^c Seoul National University   (South Korea)

Author keywords

Chronic inflammation; Cytokines; Granuloma; Titanium dioxide nanoparticles

Indexed keywords

CARBON TETRACHLORIDE; CXCL11 CHEMOKINE; GAMMA INTERFERON; IMMUNOGLOBULIN E; INTERLEUKIN 1; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 4; MONOCYTE CHEMOTACTIC PROTEIN 5; NANOPARTICLE; THYMUS AND ACTIVATION REGULATED CHEMOKINE; TITANIUM DIOXIDE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN PRESENTATION; ARTICLE; B LYMPHOCYTE; BLOOD; CHEMOTAXIS; CHRONIC INFLAMMATION; CONTROL GROUP; CYTOKINE PRODUCTION; DOSE RESPONSE; EXPERIMENTAL MOUSE; EXPERIMENTAL STUDY; GENE EXPRESSION; HISTOPATHOLOGY; IMMUNOCOMPETENT CELL; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOHISTOCHEMISTRY; LUNG PARENCHYMA; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SPLEEN; TH1 CELL; TH2 CELL;

ANIMALS; BRONCHOALVEOLAR LAVAGE FLUID; CELL PROLIFERATION; CYTOKINES; GENE EXPRESSION; IMMUNOGLOBULIN E; IMMUNOHISTOCHEMISTRY; IMMUNOPHENOTYPING; INHALATION EXPOSURE; LYMPHOCYTE SUBSETS; MALE; MICE; MICE, INBRED ICR; NANOPARTICLES; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PNEUMOCONIOSIS; RNA; TITANIUM;

MUS;

EID: 67349282414     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2009.03.005     Document Type: Article

References (38)

1. Abedi-Valugerdi M. Mercury and silver induce B cell activation and anti-nucleolar autoantibody production in outbred mouse stocks: are environmental factors more important than the susceptibility genes in connection with autoimmunity?. Clin. Exp. Immunol. 155 1 (2009) 117-124
2. Alberg T., Cassee F.R., Groeng E.C., Dybing E., and Løvik M. Fine ambient particles from various sites in europe exerted a greater IgE adjuvant effect than coarse ambient particles in a mouse model. J. Toxicol. Environ. Health A. 72 1 (2009) 1-13
3. Ameshima S., Ishizaki T., Demura Y., Imamura Y., Miyamori I., and Mitsuhashi H. Increased secretory leukoprotease inhibitor in patients with nonsmall cel lung carcinoma. Cancer 89 7 (2000) 1448-1456
4. Byun J.A., Ryu M.H., and Lee J.K. The immunomodulatory effects of 3-monochloro-1,2-propanediol on murine splenocyte and peritoneal macrophage function in vitro. Toxicol. In Vitro 20 3 (2006) 272-278
5. Chen H.W., Su S.F., Chien C.T., Lin W.H., Yu S.L., Chou C.C., Chen J.J., and Yang P.C. Titanium dioxide nanoparticles induce emphysema-like lung injury in mice. FASEB J. 20 13 (2006) E1732-E1741
6. Cho W.S., Choi M., Han B.S., Cho M., Oh J., Park K., Kim S.J., Kim S.H., and Jeong J. Inflammatory mediators induced by intratracheal instillation of ultrafine amorphous silica particles. Toxicol. Lett. 175 (2007) 24-33
7. Dai S., Wang X., Liu L., Liu J., Wu S., Huang L., Xiao X., and He D. Discovery and identification of serum amyloid a protein elevated in lung cancer serum. Sci. China C Life Sci. 50 3 (2007) 305-311
8. Driscoll K.E., and Maurer J.K. Cytokine and growth factor release by alveolar macrophages: potential biomarkers of pulmonary toxicity. Toxicol. Pathol. 19 4 (1991) 398-405
9. Fukami N., Ramachandran S., Saini D., Walter M., Chapman W., Patterson G.A., and Mohanakumar T. Antibodies to MHC class I induce autoimmunity: role in the pathogenesis of chronic rejection. J. Immunol. 182 1 (2009) 309-318
10. + interactions with matrix metallopeptidase-12: implications for matrix metallopeptidase regulation. Biochem. J. 398 3 (2006) 393-398
11. Grassian V.H., O'Shaughnessy P.T., Adamcakova-Dodd A., Pettibone J.M., and Thorne P.S. Inhalation exposure study of titanium dioxide nanoparticles with a primary particle size of 2 to 5 nm. Env. Health Perspect. 115 3 (2007) 397-402
12. Gurr J.R., Wang A.S., Chen C.H., and Jan K.Y. Ultrafine titanium dioxide particles in the absence of photoactivation can induce oxidative damage to human bronchial epithelial cells. Toxicology 213 1-2 (2005) 66-73
13. Haar C., Hassing I., Bol M., Bleumink R., and Pieters R. Ultrafine but not fine particulate matter causes airway inflammation and allergic airway sensitization to co-administered antigen in mice. Clin. Exp. Allergy 36 11 (2006) 1469-1479
14. Jousilahti P., Salomaa V., Hakala K., Rasi V., Vahtera E., and Palosuo T. The association of sensitive systemic inflammation markers with bronchial asthma. Ann. Allergy Asthma Immunol. 89 4 (2002) 381-385
15. Kang S.J., Kim B.M., Lee Y.J., and Chung H.W. Titanium dioxide nanoparticles trigger p53-mediated damage response in peripheral blood lymphocytes. Environ. Mol. Mutagen. 49 5 (2008) 399-405
16. Kleinman M.T., Sioutas C., Froines J.R., Fanning E., Hamade A., Mendez L., Meacher D., and Oldham M. Inhalation of concentrated ambient particulate matter near a heavily trafficked road stimulates antigen-induced airway responses in mice. Inhal. Toxicol. 19 (2007) 117-126
17. 2) by inhalation for two years. Toxicol. Appl. Pharmacol. 79 2 (1985) 179-192
18. Li N., and Nei A.E. The role of oxidative stress in ambient particulate matter-induced lung diseases and its implications in the toxicity of engineered nanoparticles. Free Radic. Biol. Med. 44 9 (2008) 1689-1699
19. Liu M., Sun H., Wang X., Koike T., Mishima H., Ikeda K., Watanabe T., Ochiai N., and Fan J. Association of increased expression of macrophage elastase(matrix metalloproteinase 12) with rheumatoid arthritis. Arthritis Rheum. 50 10 (2004) 3112-3117
20. Ma J.Y., and Ma J.K. The dual effect of the particulate and organic components of diesel exhaust particles on the alteration of pulmonary immune/inflammatory responses and metabolic enzymes. J. Environ. Sci. Health C Environ. Carcinog. Ecotoxicol. Rev. 20 2 (2002) 117-147
21. Manosroi A., Saraphanchotiwitthaya A., and Manosroi J. In vitro immunomodulatory effect of Pouteria cambodiana(Pierre ex Dubard) Baehni extract. J. Ethnopharmacol. 101 1-3 (2005) 90-94
22. Muller J., Huaux F., Moreau N., Misson P., Heilier J.F., Delos M., Arras M., Fonseca A., Nagy J.B., and Lison D. Respiratory toxicity of multi-wall carbon nanotubes. Toxicol. Appl. Pharmacol. 207 3 (2005) 221-231
23. Nukiwa T., Suzuki T., Fukuhara T., and Kikuchi T. Secretory leukocyte peptidase inhibitor and lung cancer. Cancer Sci. 99 5 (2008) 849-855
24. Oberdörster G., Oberdörster E., and Oberdörster J. Nanotoxicology: an emerging discipline evolving from studies of ultrafine particles. Environ. Health Perspect. 113 7 (2005) 823-839
25. Ohrui T., Zayasu K., Sato E., Matsui T., Sekizawa K., and Sasaki H. Pulmonary tuberculosis and serum IgE. Clin. Exp. Immunol. 122 1 (2000) 13-15
26. Park E., Yi J., Chung K., Ryu D., Choi J., and Park K. Oxidative stress and apoptosis induced by titanium dioxide nanoparticles in cultured BEAS-2B cells. Toxicol. Lett. 180 (2008) 222-229
27. Rahman Q., Lohani M., Dopp E., Pemsel H., Jonas L., Weiss D.G., and Schiffmann D. Evidence that ultrafine titanium dioxide induces micronuclei and apoptosis in Syrian hamster embryo fibroblasts. Environ. Health Perspect. 110 8 (2002) 797-800
28. Reeves J.F., Davies S.J., Dodd N.J.F., and Jha A.N. Hydroxyl radicals(*OH) are associated with titanium dioxide(TiO2) nanoparticle-induced cytotoxicity and oxidative DNA damage in fish cells. Mutat. Res. 640 (2008) 113-122
29. Rosenberg G.A. Matrix metalloproteinases and neuroinflammation in multiple sclerosis. Neuroscientist 8 6 (2002) 586-595
30. Sallenave J.M., Donnelly S.C., Grant I.S., Robertson C., Gauldie J., and Haslett C. Secretory leukocyte proteinase inhibitor is preferentially increased in patients with acute respiratory distress syndrome. Eur. Respir. J. 13 5 (1999) 1029-1036
31. Siegel P.D., Saxena R.K., Saxena Q.B., Ma J.K., Ma J.Y., Yin X.J., Castranova V., Al-Humadi N., and Lewis D.M. Effect of diesel exhaust particulate(DEP) on immune responses: contributions of particulate versus organic soluble components. J. Toxicol. Environ. Health A 67 3 (2004) 221-231
32. Silva I.A., Graber J., Nyland J.F., and Silbergeld E.K. In vitro HgCl2 exposure of immune cells at different stages of maturation: effects on phenotype and function. Environ. Res. 98 (2005) 341-348
33. Snider G.L. Understanding inflammation in chronic obstructive pulmonary disease: the process begins. Am. J. Respir. Crit. Care Med. 167 8 (2003) 1045-1046
34. Vendrame M., Gemma C., Pennypacker K.R., Bickford P.C., Davis, Sanberg C., Sanberg P.R., and Willing A.E. Cord blood rescues stroke-induced changes in splenocyte phenotype and function. Exp. Neurol. 199 (2006) 191-200
35. Warheit D.B., Laurence B.R., Reed K.L., Roach D.H., Reynolds G.A., and Webb T.R. Comparative pulmonary toxicity assessment of single-wall carbon nanotubes in rats. Toxicol. Sci. 77 1 (2004) 117-125
36. Warheit D.B., Borm P.J., Hennes C., and Lademann J. Testing strateges to establish the safety of nanomaterials: conclusion of an ECETOC workshop. Inhal. Toxicol. 19 8 (2007) 631-643
37. Watterberg K.L., Carmichael D.F., Gerdes J.S., Werner S., Backstrom C., and Murphy S. Secretory leukocyte protease inhibitor and lung inflammation in developing bronchopulmonary dysplasia. J. Pediatr. 125 2 (1994) 264-269
38. Yamadori I., Ohsumi S., and Taguchi K. Titanium dioxide deposition and adenocarcinoma of the lung. Acta Pathol. Jpn. 36 5 (1986) 783-790