The matricellular protein CCN1/Cyr61 is a critical regulator of sonic hedgehog in pancreatic carcinogenesis

Journal of Biological Chemistry

Volumn 287, Issue 46, 2012, Pages 38569-38579

  Haque, Inamul ^a,b   De, Archana ^a   Majumder, Monami ^a,b   Mehta, Smita ^a   McGregor, Douglas ^a,c   Banerjee, Sushanta K ^a,b,c   Van Veldhuizen, Peter ^a,b   Banerjee, Snigdha ^a,b  

^a VA Medical Center   (United States)

^b UNIVERSITY OF KANSAS MEDICAL CENTER   (United States)

^c UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMICAL ACTIVITY; CANCER STEM CELLS; DISEASE PROGRESSION; DRUG RESISTANCE; DUCTAL ADENOCARCINOMAS; GROWTH FACTOR; IN-VITRO; INTEGRIN RECEPTORS; MATRICELLULAR PROTEIN; MOLECULAR TARGETS; NUDE MICE; PANCREATIC CANCERS; PRECURSOR LESIONS; PROTEASOMAL DEGRADATION; SIGNALING PATHWAYS; SONIC HEDGEHOGS; TUMORIGENICITY;

DIAGNOSIS; PATHOLOGY; PATIENT TREATMENT; STEM CELLS;

DISEASES;

CYSTEINE RICH PROTEIN 61; INTEGRIN; NOTCH RECEPTOR; NOTCH1 RECEPTOR; PROTEASOME; SONIC HEDGEHOG PROTEIN; VITRONECTIN RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL CULTURE; CANCER GROWTH; CANCER PROGNOSIS; CANCER STEM CELL; CARCINOGENESIS; CELL MIGRATION; CELL POPULATION; CONTROLLED STUDY; DISEASE ASSOCIATION; ENZYME ACTIVITY; ENZYME DEGRADATION; ENZYME STABILITY; HUMAN; HUMAN CELL; IN VIVO STUDY; MOLECULAR PATHOLOGY; MOUSE; NONHUMAN; PANCREAS ADENOCARCINOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; TUMOR PROMOTION; TUMOR XENOGRAFT;

ANIMALS; CARCINOMA; CELL LINE, TUMOR; CYSTEINE-RICH PROTEIN 61; DISEASE PROGRESSION; DRUG RESISTANCE, NEOPLASM; GENE EXPRESSION REGULATION, NEOPLASTIC; HEDGEHOG PROTEINS; HUMANS; INTEGRINS; MALE; MICE; MICE, NUDE; MODELS, BIOLOGICAL; NEOPLASM TRANSPLANTATION; PANCREATIC NEOPLASMS; PROTEASOME ENDOPEPTIDASE COMPLEX; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION;

ERINACEIDAE; MUS MUSCULUS;

EID: 84869028821     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.389064     Document Type: Article

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