Thimerosal-Induced Apoptosis in Mouse C2C12 Myoblast Cells Occurs through Suppression of the PI3K/Akt/Survivin Pathway

PLoS ONE

Volumn 7, Issue 11, 2012, Pages

  Li, Wen Xue ^a   Chen, Si Fan ^a   Chen, Li Ping ^b   Yang, Guang Yu ^a   Li, Jun Tao ^a   Liu, Hua Zhang ^a   Zhu, Wei ^a  

^a GUANGZHOU CENTER FOR DISEASE CONTROL AND PREVENTION   (China)

^b SUN YAT SEN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

4 [5 (4 METHYL 1 PIPERAZINYL)[2,5' BI 1H BENZIMIDAZOL] 2' YL]PHENOL; CASPASE 3; CASPASE 9; CYTOCHROME C; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SMALL INTERFERING RNA; SURVIVIN; THIOMERSAL; WORTMANNIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELL CYCLE S PHASE; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DOSE RESPONSE; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; FLOW CYTOMETRY; IMMUNOBLOTTING; INCUBATION TIME; LONG TERM EXPOSURE; MITOCHONDRION; MOUSE; MYOBLAST; NONHUMAN; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS REGULATION; PROTEINASE INHIBITION; S PHASE CELL CYCLE CHECKPOINT; SIGNAL TRANSDUCTION; STAINING;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CASPASE 3; CASPASE 9; CELL CYCLE CHECKPOINTS; CELL LINE; CELL PROLIFERATION; CYTOCHROMES C; INHIBITOR OF APOPTOSIS PROTEINS; MICE; MITOCHONDRIA; MYOBLASTS; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; REPRESSOR PROTEINS; S PHASE; SIGNAL TRANSDUCTION; THIMEROSAL;

EID: 84868691831     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0049064     Document Type: Article

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