Thimerosal-induced apoptosis in human SCM1 gastric cancer cells: Activation of p38 MAP kinase and caspase-3 pathways without involvement of [Ca2+]i elevation

Toxicological Sciences

Volumn 100, Issue 1, 2007, Pages 109-117

  Liu, Shiuh Inn ^a   Huang, Chorng Chih ^b   Huang, Chun Jen ^c,d   Wang, Being Whey ^a   Chang, Po Min ^a   Fang, Yi Chien ^e   Chen, Wei Chuan ^f   Wang, Jue Long ^a   Lu, Yih Chau ^a   Chu, Sau Tung ^a   Chou, Chiang Ting ^a   Jan, Chung Ren ^a  

^a KAOHSIUNG VETERANS GENERAL HOSPITAL   (Taiwan)

^b TZU HUI INSTITUTE OF TECHNOLOGY   (Taiwan)

^c KAOHSIUNG MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^d TIAN SHENG MEMORIAL HOSPITAL   (Taiwan)

^e ZUOYING ARMED FORCES GENERAL HOSPITAL   (Taiwan)

^f PINGTUNG CHRISTIAN HOSPITAL   (Taiwan)

Author keywords

Apoptosis; Caspase 3; Gastric cancer cells; MAPKs; Thimerosal

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CALCIUM ION; CASPASE 3; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PROPIDIUM IODIDE; STRESS ACTIVATED PROTEIN KINASE; THIOMERSAL;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CALCIUM TRANSPORT; CANCER CELL; CANCER CELL CULTURE; CELL PROTECTION; CELL VIABILITY; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; EXTRACELLULAR SPACE; HUMAN; HUMAN CELL; IMMUNOBLOTTING; STOMACH CANCER;

ANTHRACENES; APOPTOSIS; CALCIUM SIGNALING; CASPASE 3; CELL LINE, TUMOR; CELL SURVIVAL; CHELATING AGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; EGTAZIC ACID; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FLAVONOIDS; HUMANS; IMIDAZOLES; JNK MITOGEN-ACTIVATED PROTEIN KINASES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PRESERVATIVES, PHARMACEUTICAL; PROTEIN KINASE INHIBITORS; PYRIDINES; STOMACH NEOPLASMS; THIMEROSAL; TIME FACTORS;

EID: 35448969417     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfm205     Document Type: Article

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