Bivalent ligands targeting multiple pathological factors involved in Alzheimer's disease

ACS Medicinal Chemistry Letters

Volumn 3, Issue 11, 2012, Pages 942-946

  Liu, Kai ^a   Gandhi, Ronak ^a   Chen, Jiangmin ^a   Zhang, Shijun ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

A oligomers; Alzheimer's disease; antioxidant; bivalent ligands; metal chelating; multifunctional

Indexed keywords

AMYLOID BETA PROTEIN; ANTIOXIDANT; CARBENE; CARBON; CARBONYL DERIVATIVE; CHOLESTEROL; CHOLESTERYLAMINE; COPPER; CURCUMIN; IRON; LIGAND; NEUROPROTECTIVE AGENT; OLIGOMER; UNCLASSIFIED DRUG; ZINC;

ALZHEIMER DISEASE; ANTIOXIDANT ACTIVITY; ARTICLE; ATOM; BIOLOGICAL ACTIVITY; CHELATION; COMPLEX FORMATION; CONTROLLED STUDY; DRUG DESIGN; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; NEUROBLASTOMA CELL; NEUROPROTECTION; NEUROTOXICITY; OLIGOMERIZATION; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

EID: 84868680596     PISSN: None     EISSN: 19485875     Source Type: Journal    
DOI: 10.1021/ml300229y     Document Type: Article

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