Cancer-associated variants and a common polymorphism of MUTYH exhibit reduced repair of oxidative DNA damage using a GFP-based assay in mammalian cells

Carcinogenesis

Volumn 33, Issue 11, 2012, Pages 2301-2309

  Raetz, Alan G ^a   Xie, Yali ^b   Kundu, Sucharita ^a   Brinkmeyer, Megan K ^a   Chang, Cindy ^a   David, Sheila S ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b HEALTH SCIENCES CENTRE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

8 HYDROXYGUANINE; ADENINE; GREEN FLUORESCENT PROTEIN;

ANIMAL CELL; ARTICLE; CANCER RISK; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; ENZYME ACTIVITY; FIBROBLAST; FLUORESCENCE ANALYSIS; GENE; GENE FREQUENCY; GENE MUTATION; GENETIC POLYMORPHISM; GENETIC VARIABILITY; HUMAN; IN VITRO STUDY; INSECT CELL; MISMATCH REPAIR; MOUSE; MUTYH GENE; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; POLYPOSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; WILD TYPE;

ANIMALS; APOPTOSIS; BIOLOGICAL ASSAY; BLOTTING, WESTERN; CELL PROLIFERATION; CELLS, CULTURED; COLORECTAL NEOPLASMS; DNA DAMAGE; DNA GLYCOSYLASES; DNA REPAIR; EMBRYO, MAMMALIAN; FIBROBLASTS; FLOW CYTOMETRY; GREEN FLUORESCENT PROTEINS; HUMANS; LUNG NEOPLASMS; MICE; MICE, KNOCKOUT; MUTATION; N-GLYCOSYL HYDROLASES; POLYMORPHISM, GENETIC; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 84868617486     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgs270     Document Type: Article

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