Functional analysis of MUTYH mutated proteins associated with familial adenomatous polyposis

DNA Repair

Volumn 9, Issue 6, 2010, Pages 700-707

  D'Agostino, Vito G ^a   Minoprio, Anna ^b   Torreri, Paola ^b   Marinoni, Ilaria ^a   Bossa, Cecilia ^b   Petrucci, Tamara C ^b   Albertini, Alessandra M ^a   Ranzani, Guglielmina N ^a   Bignami, Margherita ^b   Mazzei, Filomena ^b  

^a UNIVERSITY OF PAVIA   (Italy)

^b ISTITUTO SUPERIORE DI SANITÀ   (Italy)

Author keywords

Base excision repair; DNA glycosylase assay; MUTYH; MUTYH mutants; MUTYH associated polyposis; Surface plasmon resonance

Indexed keywords

8 HYDROXYGUANINE; ADENINE; DNA GLYCOSYLASE MUTY; DNA POLYMERASE; GUANINE; THYMINE; 8-HYDROXYGUANINE; DNA; DNA GLYCOSYLTRANSFERASE; MALTOSE BINDING PROTEIN; MUTANT PROTEIN; PERIPLASMIC BINDING PROTEIN;

ARTICLE; BINDING AFFINITY; CANCER SUSCEPTIBILITY; COLORECTAL CANCER; CONTROLLED STUDY; DNA REPAIR; ENZYME ACTIVITY; ENZYME SUBSTRATE; ESCHERICHIA COLI; FAMILIAL COLON POLYPOSIS; GEL MOBILITY SHIFT ASSAY; GENE FUNCTION; GENE MUTATION; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC VARIABILITY; GEOBACILLUS STEAROTHERMOPHILUS; GERM LINE; HUMAN; HUMAN CELL; MOLECULAR RECOGNITION; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; OXIDATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PURIFICATION; SURFACE PLASMON RESONANCE; WILD TYPE; ANALOGS AND DERIVATIVES; CHEMISTRY; COLON POLYPOSIS; ENZYME ACTIVE SITE; GENETICS; KINETICS; METABOLISM; MUTATION; NUCLEOTIDE SEQUENCE;

ADENOMATOUS POLYPOSIS COLI; BASE SEQUENCE; CATALYTIC DOMAIN; DNA; DNA GLYCOSYLASES; GUANINE; HUMANS; KINETICS; MUTANT PROTEINS; MUTATION; PERIPLASMIC BINDING PROTEINS; SURFACE PLASMON RESONANCE; MALTOSE-BINDING PROTEINS;

BACTERIA (MICROORGANISMS);

EID: 77952582935     PISSN: 15687864     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.dnarep.2010.03.008     Document Type: Article

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