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Volumn 33, Issue 11, 2012, Pages 2250-2259

The TNF-α/ROS/HIF-1-induced upregulation of foxMI expression promotes HCC proliferation and resistance to apoptosis

Author keywords

[No Author keywords available]

Indexed keywords

BETA ACTIN; CYCLIN B1; CYCLIN D1; HYPOXIA INDUCIBLE FACTOR 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 3; HYPOXIA INDUCIBLE FACTOR 4; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR FOXMI; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 84868616470     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgs249     Document Type: Article
Times cited : (102)

References (46)
  • 1
    • 0035901090 scopus 로고    scopus 로고
    • Inflammation and cancer: back to Virchow?
    • Balkwill, F. et al. (2001) Inflammation and cancer: back to Virchow? Lancet, 357, 539-545.
    • (2001) Lancet , vol.357 , pp. 539-545
    • Balkwill, F.1
  • 2
    • 76049097477 scopus 로고    scopus 로고
    • HCV-related hepatocellular carcinoma: from chronic inflammation to cancer
    • Castello, G. et al. (2010) HCV-related hepatocellular carcinoma: from chronic inflammation to cancer. Clin. Immunol., 134, 237-250.
    • (2010) Clin. Immunol. , vol.134 , pp. 237-250
    • Castello, G.1
  • 3
    • 25844459154 scopus 로고    scopus 로고
    • NF-kappaB: linking inflammation and immunity to cancer development and progression
    • Karin, M. et al. (2005) NF-kappaB: linking inflammation and immunity to cancer development and progression. Nat. Rev. Immunol., 5, 749-759.
    • (2005) Nat. Rev. Immunol. , vol.5 , pp. 749-759
    • Karin, M.1
  • 4
    • 0036584028 scopus 로고    scopus 로고
    • Development of anti-TNF therapy for rheumatoid arthritis
    • Feldmann, M. (2002) Development of anti-TNF therapy for rheumatoid arthritis. Nat. Rev. Immunol., 2, 364-371.
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 364-371
    • Feldmann, M.1
  • 5
    • 0034006016 scopus 로고    scopus 로고
    • HIF-1: mediator of physiological and pathophysiological responses to hypoxia
    • Semenza, G.L. (2000) HIF-1: mediator of physiological and pathophysiological responses to hypoxia. J. Appl. Physiol., 88, 1474-1480.
    • (2000) J. Appl. Physiol. , vol.88 , pp. 1474-1480
    • Semenza, G.L.1
  • 6
    • 0035917808 scopus 로고    scopus 로고
    • Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation
    • Jaakkola, P. et al. (2001) Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation. Science, 292, 468-472.
    • (2001) Science , vol.292 , pp. 468-472
    • Jaakkola, P.1
  • 7
    • 0035887011 scopus 로고    scopus 로고
    • FIH-1: a novel protein that interacts with HIF-1alpha and VHL to mediate repression of HIF-1 transcriptional activity
    • Mahon, P.C. et al. (2001) FIH-1: a novel protein that interacts with HIF-1alpha and VHL to mediate repression of HIF-1 transcriptional activity. Genes. Dev., 15, 2675-2686.
    • (2001) Genes. Dev. , vol.15 , pp. 2675-2686
    • Mahon, P.C.1
  • 8
    • 0037119415 scopus 로고    scopus 로고
    • Hsp90 regulates a von Hippel Lindau-independent hypoxia-inducible factor-1 alpha-degradative pathway
    • Isaacs, J.S. et al. (2002) Hsp90 regulates a von Hippel Lindau-independent hypoxia-inducible factor-1 alpha-degradative pathway. J. Biol. Chem., 277, 29936-29944.
    • (2002) J. Biol. Chem. , vol.277 , pp. 29936-29944
    • Isaacs, J.S.1
  • 9
    • 0030787469 scopus 로고    scopus 로고
    • Transactivation and inhibitory domains of hypoxia-inducible factor 1alpha. Modulation of transcriptional activity by oxygen tension
    • Jiang, B.H. et al. (1997) Transactivation and inhibitory domains of hypoxia-inducible factor 1alpha. Modulation of transcriptional activity by oxygen tension. J. Biol. Chem., 272, 19253-19260.
    • (1997) J. Biol. Chem. , vol.272 , pp. 19253-19260
    • Jiang, B.H.1
  • 10
    • 18844444774 scopus 로고    scopus 로고
    • HIF-1alpha, STAT3 CBP/p300 and Ref-1/APE are components of a transcriptional complex that regulates Src-dependent hypoxia-induced expression of VEGF in pancreatic and prostate carcinomas
    • Gray, M.J. et al. (2005) HIF-1alpha, STAT3, CBP/p300 and Ref-1/APE are components of a transcriptional complex that regulates Src-dependent hypoxia-induced expression of VEGF in pancreatic and prostate carcinomas. Oncogene, 24, 3110-3120.
    • (2005) Oncogene , vol.24 , pp. 3110-3120
    • Gray, M.J.1
  • 11
    • 77956713136 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-1 activation in nonhypoxic conditions: the essential role of mitochondrial-derived reactive oxygen species
    • Patten, D.A. et al. (2010) Hypoxia-inducible factor-1 activation in nonhypoxic conditions: the essential role of mitochondrial-derived reactive oxygen species. Mol. Biol. Cell., 21, 3247-3257.
    • (2010) Mol. Biol. Cell. , vol.21 , pp. 3247-3257
    • Patten, D.A.1
  • 12
    • 0037073695 scopus 로고    scopus 로고
    • Induction of hypoxia-inducible factor-1alpha by transcriptional and translational mechanisms
    • Page, E.L. et al. (2002) Induction of hypoxia-inducible factor-1alpha by transcriptional and translational mechanisms. J. Biol. Chem., 277, 48403-48409.
    • (2002) J. Biol. Chem. , vol.277 , pp. 48403-48409
    • Page, E.L.1
  • 13
    • 33644542405 scopus 로고    scopus 로고
    • The Forkhead Box m1 transcription factor stimulates the proliferation of tumor cells during development of lung cancer
    • Kim, I.M. et al. (2006) The Forkhead Box m1 transcription factor stimulates the proliferation of tumor cells during development of lung cancer. Cancer Res., 66, 2153-2161.
    • (2006) Cancer Res , vol.66 , pp. 2153-2161
    • Kim, I.M.1
  • 14
    • 0031020158 scopus 로고    scopus 로고
    • Hepatocyte nuclear factor 3/fork head homolog 11 is expressed in proliferating epithelial and mesenchymal cells of embryonic and adult tissues
    • Ye, H. et al. (1997) Hepatocyte nuclear factor 3/fork head homolog 11 is expressed in proliferating epithelial and mesenchymal cells of embryonic and adult tissues. Mol. Cell. Biol., 17, 1626-1641.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 1626-1641
    • Ye, H.1
  • 15
    • 0030741972 scopus 로고    scopus 로고
    • Molecular analysis of a novel winged helix protein, WIN. Expression pattern, DNA binding property, and alternative splicing within the DNA binding domain
    • Yao, K.M. et al. (1997) Molecular analysis of a novel winged helix protein, WIN. Expression pattern, DNA binding property, and alternative splicing within the DNA binding domain. J. Biol. Chem., 272, 19827-19836.
    • (1997) J. Biol. Chem. , vol.272 , pp. 19827-19836
    • Yao, K.M.1
  • 16
    • 0033506486 scopus 로고    scopus 로고
    • Premature expression of the winged helix transcription factor HFH-11B in regenerating mouse liver accelerates hepatocyte entry into S phase
    • Ye, H. et al. (1999) Premature expression of the winged helix transcription factor HFH-11B in regenerating mouse liver accelerates hepatocyte entry into S phase. Mol. Cell. Biol., 19, 8570-8580.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 8570-8580
    • Ye, H.1
  • 17
    • 0035914037 scopus 로고    scopus 로고
    • Over-expression of FoxM1 stimulates cyclin B1 expression
    • Leung, T.W. et al. (2001) Over-expression of FoxM1 stimulates cyclin B1 expression. FEBS Lett., 507, 59-66.
    • (2001) FEBS Lett , vol.507 , pp. 59-66
    • Leung, T.W.1
  • 18
    • 0037113939 scopus 로고    scopus 로고
    • Increased hepatic Forkhead Box M1B (FoxM1B) levels in old-aged mice stimulated liver regeneration through diminished p27Kip1 protein levels and increased Cdc25B expression
    • Wang, X. et al. (2002) Increased hepatic Forkhead Box M1B (FoxM1B) levels in old-aged mice stimulated liver regeneration through diminished p27Kip1 protein levels and increased Cdc25B expression. J. Biol. Chem., 277, 44310-44316.
    • (2002) J. Biol. Chem. , vol.277 , pp. 44310-44316
    • Wang, X.1
  • 19
    • 32944459113 scopus 로고    scopus 로고
    • Increased levels of the FoxM1 transcription factor accelerate development and progression of prostate carcinomas in both TRAMP and LADY transgenic mice
    • Kalin, T.V. et al. (2006) Increased levels of the FoxM1 transcription factor accelerate development and progression of prostate carcinomas in both TRAMP and LADY transgenic mice. Cancer Res., 66, 1712-1720.
    • (2006) Cancer Res , vol.66 , pp. 1712-1720
    • Kalin, T.V.1
  • 20
    • 33645734725 scopus 로고    scopus 로고
    • FoxM1B is overexpressed in human glioblastomas and critically regulates the tumorigenicity of glioma cells
    • Liu, M. et al. (2006) FoxM1B is overexpressed in human glioblastomas and critically regulates the tumorigenicity of glioma cells. Cancer Res., 66, 3593-3602.
    • (2006) Cancer Res , vol.66 , pp. 3593-3602
    • Liu, M.1
  • 21
    • 66349107985 scopus 로고    scopus 로고
    • Forkhead box M1B is a determinant of rat susceptibility to hepatocarcinogenesis and sustains ERK activity in human HCC
    • Calvisi, D.F. et al. (2009) Forkhead box M1B is a determinant of rat susceptibility to hepatocarcinogenesis and sustains ERK activity in human HCC. Gut, 58, 679-687.
    • (2009) Gut , vol.58 , pp. 679-687
    • Calvisi, D.F.1
  • 22
    • 84857439515 scopus 로고    scopus 로고
    • AKT (v-akt murine thymoma viral oncogene homolog 1) and N-Ras (neuroblastoma ras viral oncogene homolog) coactivation in the mouse liver promotes rapid carcinogenesis by way of mTOR (mammalian target of rapamycin complex 1), FOXM1 (forkhead box M1)/SKP2, and c-Myc pathways
    • Ho, C. et al. (2012) AKT (v-akt murine thymoma viral oncogene homolog 1) and N-Ras (neuroblastoma ras viral oncogene homolog) coactivation in the mouse liver promotes rapid carcinogenesis by way of mTOR (mammalian target of rapamycin complex 1), FOXM1 (forkhead box M1)/SKP2, and c-Myc pathways. Hepatology, 55, 833-845.
    • (2012) Hepatology , vol.55 , pp. 833-845
    • Ho, C.1
  • 23
    • 79955463277 scopus 로고    scopus 로고
    • FOXM1 expression predicts the prognosis in hepatocellular carcinoma patients after orthotopic liver transplantation combined with the Milan criteria
    • Sun, H. et al. (2011) FOXM1 expression predicts the prognosis in hepatocellular carcinoma patients after orthotopic liver transplantation combined with the Milan criteria. Cancer Lett., 306, 214-222.
    • (2011) Cancer Lett , vol.306 , pp. 214-222
    • Sun, H.1
  • 24
    • 79954518901 scopus 로고    scopus 로고
    • Overexpression of Forkhead box M1 protein associates with aggressive tumor features and poor prognosis of hepatocellular carcinoma
    • Sun, H.C. et al. (2011) Overexpression of Forkhead box M1 protein associates with aggressive tumor features and poor prognosis of hepatocellular carcinoma. Oncol. Rep., 25, 1533-1539.
    • (2011) Oncol. Rep. , vol.25 , pp. 1533-1539
    • Sun, H.C.1
  • 25
    • 11144353897 scopus 로고    scopus 로고
    • Foxm1b transcription factor is essential for development of hepatocellular carcinomas and is negatively regulated by the p19ARF tumor suppressor
    • Kalinichenko, V.V. et al. (2004) Foxm1b transcription factor is essential for development of hepatocellular carcinomas and is negatively regulated by the p19ARF tumor suppressor. Genes Dev, 18, 830-850.
    • (2004) Genes Dev , vol.18 , pp. 830-850
    • Kalinichenko, V.V.1
  • 26
    • 33846006533 scopus 로고    scopus 로고
    • A cell-penetrating ARF peptide inhibitor of FoxM1 in mouse hepatocellular carcinoma treatment
    • Gusarova, G.A. et al. (2007) A cell-penetrating ARF peptide inhibitor of FoxM1 in mouse hepatocellular carcinoma treatment. J. Clin. Invest., 117, 99-111.
    • (2007) J. Clin. Invest. , vol.117 , pp. 99-111
    • Gusarova, G.A.1
  • 27
    • 61449153846 scopus 로고    scopus 로고
    • Transcriptional up-regulation of FoxM1 in response to hypoxia is mediated by HIF-1
    • Xia, L.M. et al. (2009) Transcriptional up-regulation of FoxM1 in response to hypoxia is mediated by HIF-1. J. Cell Biochem., 106, 247-256.
    • (2009) J. Cell Biochem. , vol.106 , pp. 247-256
    • Xia, L.M.1
  • 28
    • 28844480321 scopus 로고    scopus 로고
    • Management of hepatocellular carcinoma
    • Bruix, J. et al. (2005) Management of hepatocellular carcinoma. Hepatology, 42, 1208-1236.
    • (2005) Hepatology , vol.42 , pp. 1208-1236
    • Bruix, J.1
  • 29
    • 77949535410 scopus 로고    scopus 로고
    • Negative feedback control of HIF-1 through REDD1-regulated ROS suppresses tumorigenesis
    • Horak, P. et al. (2010) Negative feedback control of HIF-1 through REDD1-regulated ROS suppresses tumorigenesis. Proc Natl Acad Sci U S A, 107, 4675-4680.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 4675-4680
    • Horak, P.1
  • 30
    • 70450278715 scopus 로고    scopus 로고
    • Reactive oxygen species-generating mitochondrial DNA mutation up-regulates hypoxia-inducible factor-1alpha gene transcription via phosphatidylinositol 3-kinase-Akt/protein kinase C/histone deacetylase pathway
    • Koshikawa, N. et al. (2009) Reactive oxygen species-generating mitochondrial DNA mutation up-regulates hypoxia-inducible factor-1alpha gene transcription via phosphatidylinositol 3-kinase-Akt/protein kinase C/histone deacetylase pathway. J. Biol. Chem., 284, 33185-33194.
    • (2009) J. Biol. Chem. , vol.284 , pp. 33185-33194
    • Koshikawa, N.1
  • 31
    • 81155154300 scopus 로고    scopus 로고
    • Alsin and SOD1(G93A) proteins regulate endosomal reactive oxygen species production by glial cells and proinflammatory pathways responsible for neurotoxicity
    • Li, Q. et al. (2011) Alsin and SOD1(G93A) proteins regulate endosomal reactive oxygen species production by glial cells and proinflammatory pathways responsible for neurotoxicity. J Biol Chem, 286, 40151-40162.
    • (2011) J Biol Chem , vol.286 , pp. 40151-40162
    • Li, Q.1
  • 32
    • 84455161897 scopus 로고    scopus 로고
    • Glucocorticoids and tumor necrosis factor alpha increase oxidative stress and suppress Wnt protein signaling in osteoblasts
    • Almeida, M. et al. (2011) Glucocorticoids and tumor necrosis factor alpha increase oxidative stress and suppress Wnt protein signaling in osteoblasts. J. Biol. Chem., 286, 44326-44335.
    • (2011) J. Biol. Chem. , vol.286 , pp. 44326-44335
    • Almeida, M.1
  • 33
    • 67349162130 scopus 로고    scopus 로고
    • Tumour necrosis factor and cancer
    • Balkwill, F. (2009) Tumour necrosis factor and cancer. Nat Rev Cancer, 9, 361-371.
    • (2009) Nat Rev Cancer , vol.9 , pp. 361-371
    • Balkwill, F.1
  • 34
    • 11144280578 scopus 로고    scopus 로고
    • Identification and validation of commonly overexpressed genes in solid tumors by comparison of microarray data
    • Pilarsky, C. et al. (2004) Identification and validation of commonly overexpressed genes in solid tumors by comparison of microarray data. Neoplasia, 6, 744-750.
    • (2004) Neoplasia , vol.6 , pp. 744-750
    • Pilarsky, C.1
  • 35
    • 84873092630 scopus 로고    scopus 로고
    • Foxm1 transcription factor is required for macrophage migration during lung inflammation and tumor formation
    • [Epub ahead of print]
    • Balli, D. et al. (2011) Foxm1 transcription factor is required for macrophage migration during lung inflammation and tumor formation. Oncogene. [Epub ahead of print]
    • (2011) Oncogene
    • Balli, D.1
  • 36
    • 70350572180 scopus 로고    scopus 로고
    • FoxM1, a critical regulator of oxidative stress during oncogenesis
    • Park, H.J. et al. (2009) FoxM1, a critical regulator of oxidative stress during oncogenesis. EMBO J., 28, 2908-2918.
    • (2009) EMBO J , vol.28 , pp. 2908-2918
    • Park, H.J.1
  • 37
    • 0029051439 scopus 로고
    • Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension
    • Wang, G.L. et al. (1995) Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension. Proc. Natl. Acad. Sci. U. S. A., 92, 5510-5514.
    • (1995) Proc. Natl. Acad. Sci. U. S. A. , vol.92 , pp. 5510-5514
    • Wang, G.L.1
  • 38
    • 0028816847 scopus 로고
    • Purification and characterization of hypoxia-inducible factor 1
    • Wang, G.L. et al. (1995) Purification and characterization of hypoxia-inducible factor 1. J Biol Chem, 270, 1230-1237.
    • (1995) J Biol Chem , vol.270 , pp. 1230-1237
    • Wang, G.L.1
  • 39
    • 0028973482 scopus 로고
    • Requirement for generation of H2O2 for platelet-derived growth factor signal transduction
    • Sundaresan, M. et al. (1995) Requirement for generation of H2O2 for platelet-derived growth factor signal transduction. Science, 270, 296-299.
    • (1995) Science , vol.270 , pp. 296-299
    • Sundaresan, M.1
  • 40
    • 8344260568 scopus 로고    scopus 로고
    • Ferritin heavy chain upregulation by NF-kappaB inhibits TNFalpha-induced apoptosis by suppressing reactive oxygen species
    • Pham, C.G. et al. (2004) Ferritin heavy chain upregulation by NF-kappaB inhibits TNFalpha-induced apoptosis by suppressing reactive oxygen species. Cell, 119, 529-542.
    • (2004) Cell , vol.119 , pp. 529-542
    • Pham, C.G.1
  • 41
    • 0034733807 scopus 로고    scopus 로고
    • Redox-dependent signal transduction
    • Finkel, T. (2000) Redox-dependent signal transduction. FEBS Lett., 476, 52-54.
    • (2000) FEBS Lett , vol.476 , pp. 52-54
    • Finkel, T.1
  • 42
    • 79952184583 scopus 로고    scopus 로고
    • Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1-associated periodic syndrome (TRAPS)
    • Bulua, A.C. et al. (2011) Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1-associated periodic syndrome (TRAPS). J. Exp. Med., 208, 519-533.
    • (2011) J. Exp. Med. , vol.208 , pp. 519-533
    • Bulua, A.C.1
  • 43
    • 85047692516 scopus 로고    scopus 로고
    • Signalling pathways of the TNF superfamily: a double-edged sword
    • Aggarwal, B.B. (2003) Signalling pathways of the TNF superfamily: a double-edged sword. Nat Rev Immunol, 3, 745-756.
    • (2003) Nat Rev Immunol , vol.3 , pp. 745-756
    • Aggarwal, B.B.1
  • 44
    • 76949084622 scopus 로고    scopus 로고
    • TNF-alpha/NF-kappaB/Snail pathway in cancer cell migration and invasion
    • Wu, Y. et al. (2010) TNF-alpha/NF-kappaB/Snail pathway in cancer cell migration and invasion. Br. J. Cancer., 102, 639-644.
    • (2010) Br. J. Cancer. , vol.102 , pp. 639-644
    • Wu, Y.1
  • 45
    • 0038742813 scopus 로고    scopus 로고
    • Recruitment of TNF receptor 1 to lipid rafts is essential for TNFalpha-mediated NF-kappaB activation
    • Legler, D.F. et al. (2003) Recruitment of TNF receptor 1 to lipid rafts is essential for TNFalpha-mediated NF-kappaB activation. Immunity, 18, 655-664.
    • (2003) Immunity , vol.18 , pp. 655-664
    • Legler, D.F.1
  • 46
    • 14044278251 scopus 로고    scopus 로고
    • Death receptor signaling
    • Lavrik, I. et al. (2005) Death receptor signaling. J. Cell Sci., 118, 265-267.
    • (2005) J. Cell Sci. , vol.118 , pp. 265-267
    • Lavrik, I.1


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