-
1
-
-
0030043970
-
Prognostic significance of CCND1 (cyclin D1) overexpression in primary resected non-small-cell lung cancer
-
Betticher DC, Heighway J, Hasleton PS, Altermatt HJ, Ryder WD, Cerny T, Thatcher N. 1996. Prognostic significance of CCND1 (cyclin D1) overexpression in primary resected non-small-cell lung cancer. Br J Cancer 73:294-300.
-
(1996)
Br J Cancer
, vol.73
, pp. 294-300
-
-
Betticher, D.C.1
Heighway, J.2
Hasleton, P.S.3
Altermatt, H.J.4
Ryder, W.D.5
Cerny, T.6
Thatcher, N.7
-
2
-
-
0033514441
-
Inhibition of cyclin-dependent kinase 2 by p21 is necessary for retinoblastoma proteinmediated G1 arrest after γ-irradiation
-
Brugarolas J, Moberg K, Boyd SD, Taya Y, Jacks T, Lees JA. 1999. Inhibition of cyclin-dependent kinase 2 by p21 is necessary for retinoblastoma proteinmediated G1 arrest after γ-irradiation. Proc Natl Acad Sci USA 96:1002-1007.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 1002-1007
-
-
Brugarolas, J.1
Moberg, K.2
Boyd, S.D.3
Taya, Y.4
Jacks, T.5
Lees, J.A.6
-
3
-
-
0036387193
-
Forkhead transcription factors: Key players in development and metabolism
-
Carlsson P, Mahlapuu M. 2002. Forkhead transcription factors: Key players in development and metabolism. Dev Biol 250:1-23.
-
(2002)
Dev Biol
, vol.250
, pp. 1-23
-
-
Carlsson, P.1
Mahlapuu, M.2
-
4
-
-
33745685879
-
Role of hypoxia-inducible factor (HIF)-1α versus HIF-2α in the regulation of HIF target genes in response to hypoxia, insulin-like growth factor-I, or loss of von Hippel-Lindau function: Implications for targeting the HIF pathway
-
Carroll VA, Ashcroft M. 2006. Role of hypoxia-inducible factor (HIF)-1α versus HIF-2α in the regulation of HIF target genes in response to hypoxia, insulin-like growth factor-I, or loss of von Hippel-Lindau function: Implications for targeting the HIF pathway. Cancer Res 66:6264-6270.
-
(2006)
Cancer Res
, vol.66
, pp. 6264-6270
-
-
Carroll, V.A.1
Ashcroft, M.2
-
5
-
-
0345017786
-
Transcription factors in liver development, differentiation, and regeneration
-
Costa RH, Kalinichenko VV, Holterman AX, Wang X. 2003. Transcription factors in liver development, differentiation, and regeneration. Hepatology 38:1331-1347.
-
(2003)
Hepatology
, vol.38
, pp. 1331-1347
-
-
Costa, R.H.1
Kalinichenko, V.V.2
Holterman, A.X.3
Wang, X.4
-
7
-
-
31544472829
-
Cyclin B1 and other cyclins as tumor antigens in immunosurveillance and immunotherapy of cancer
-
Egloff AM, Vella LA, Finn OJ. 2006. Cyclin B1 and other cyclins as tumor antigens in immunosurveillance and immunotherapy of cancer. Cancer Res 66:6-9.
-
(2006)
Cancer Res
, vol.66
, pp. 6-9
-
-
Egloff, A.M.1
Vella, L.A.2
Finn, O.J.3
-
9
-
-
4444257379
-
The biology of hypoxia: The role of oxygen sensing in development, normal function, and disease
-
Giaccia AJ, Simon MC, Johnson R. 2004. The biology of hypoxia: The role of oxygen sensing in development, normal function, and disease. Genes Dev 18:2183-2194.
-
(2004)
Genes Dev
, vol.18
, pp. 2183-2194
-
-
Giaccia, A.J.1
Simon, M.C.2
Johnson, R.3
-
10
-
-
18844444774
-
HIF-1α, STAT3, CBP/p300 and Ref-1/APE are components of a transcriptional complex that regulates Src-dependent hypoxia-induced expression of VEGF in pancreatic and prostate carcinomas
-
Gray MJ, Zhang J, Ellis LM, Semenza GL, Evans DB, Watowich SS, Gallick GE. 2005 HIF-1α, STAT3, CBP/p300 and Ref-1/APE are components of a transcriptional complex that regulates Src-dependent hypoxia-induced expression of VEGF in pancreatic and prostate carcinomas. Oncogene 24:3110-3120.
-
(2005)
Oncogene
, vol.24
, pp. 3110-3120
-
-
Gray, M.J.1
Zhang, J.2
Ellis, L.M.3
Semenza, G.L.4
Evans, D.B.5
Watowich, S.S.6
Gallick, G.E.7
-
11
-
-
0036359548
-
Hypoxia - A key regulatory factor in tumour growth
-
Harris AL. 2002. Hypoxia - A key regulatory factor in tumour growth. Nat Rev Cancer 2:38-47.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 38-47
-
-
Harris, A.L.1
-
12
-
-
33748799418
-
Cyclin-B1-mediated inhibition of excess separase is required for timely chromosome disjunction
-
Holland AJ, Taylor SS. 2006. Cyclin-B1-mediated inhibition of excess separase is required for timely chromosome disjunction. J Cell Sci 119:3325-3336.
-
(2006)
J Cell Sci
, vol.119
, pp. 3325-3336
-
-
Holland, A.J.1
Taylor, S.S.2
-
13
-
-
33645864081
-
Human endogenous retroviral pol RNA and protein detected and identified in the blood of individuals with schizophrenia
-
Huang WJ, Liu ZC, Wei W, Wang GH, Wu JG, Zhu F. 2006. Human endogenous retroviral pol RNA and protein detected and identified in the blood of individuals with schizophrenia. Schizophr Res 83:193-199.
-
(2006)
Schizophr Res
, vol.83
, pp. 193-199
-
-
Huang, W.J.1
Liu, Z.C.2
Wei, W.3
Wang, G.H.4
Wu, J.G.5
Zhu, F.6
-
14
-
-
0037119415
-
Hsp90 regulates a VHL-independent HIF-1αdegradative pathway
-
Isaacs JS, Jung YJ, Mimnaugh EG, Martinez A, Cuttitta F, Neckers LM. 2002. Hsp90 regulates a VHL-independent HIF-1αdegradative pathway. J Biol Chem 277:29936-29944.
-
(2002)
J Biol Chem
, vol.277
, pp. 29936-29944
-
-
Isaacs, J.S.1
Jung, Y.J.2
Mimnaugh, E.G.3
Martinez, A.4
Cuttitta, F.5
Neckers, L.M.6
-
15
-
-
0030787469
-
Transactivation and inhibitory domains of hypoxia inducible factor 1α. Modulation of transcriptional activity by oxygen tension
-
Jiang BH, Zheng JZ, Leung SW, Roe R, Semenza GL. 1997. Transactivation and inhibitory domains of hypoxia inducible factor 1α. Modulation of transcriptional activity by oxygen tension. J Biol Chem 272:19253-19260.
-
(1997)
J Biol Chem
, vol.272
, pp. 19253-19260
-
-
Jiang, B.H.1
Zheng, J.Z.2
Leung, S.W.3
Roe, R.4
Semenza, G.L.5
-
16
-
-
32944459113
-
Increased levels of the FoxM1 transcription factor accelerate development and progression of prostate carcinomas in both TRAMP and LADY transgenic mice
-
Kalin TV, Wang IC, Ackerson TJ, Major ML, Detrisac CJ, Kalinichenko VV, Lyubimov A, Costa RH. 2006. Increased levels of the FoxM1 transcription factor accelerate development and progression of prostate carcinomas in both TRAMP and LADY transgenic mice. Cancer Res 66:1712-1720.
-
(2006)
Cancer Res
, vol.66
, pp. 1712-1720
-
-
Kalin, T.V.1
Wang, I.C.2
Ackerson, T.J.3
Major, M.L.4
Detrisac, C.J.5
Kalinichenko, V.V.6
Lyubimov, A.7
Costa, R.H.8
-
17
-
-
11144353897
-
Foxm1b transcription factor is essential for development of hepatocellular carcinomas and is negatively regulated by the p19ARF tumor suppressor
-
Kalinichenko VV, Major ML, Wang X, Petrovic V, Kuechle J, Yoder HM, Dennewitz MB, Shin B, Datta A, Raychaudhuri P, Costa RH. 2004. Foxm1b transcription factor is essential for development of hepatocellular carcinomas and is negatively regulated by the p19ARF tumor suppressor. Genes Dev 18:830-850.
-
(2004)
Genes Dev
, vol.18
, pp. 830-850
-
-
Kalinichenko, V.V.1
Major, M.L.2
Wang, X.3
Petrovic, V.4
Kuechle, J.5
Yoder, H.M.6
Dennewitz, M.B.7
Shin, B.8
Datta, A.9
Raychaudhuri, P.10
Costa, R.H.11
-
18
-
-
3042665524
-
Hypoxia inhibits tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by blocking Bax translocation
-
Kim M, Park SY, Pai HS, Kim TH, Billiar TR, Seol DW. 2004. Hypoxia inhibits tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by blocking Bax translocation. Cancer Res 64:4078-4081.
-
(2004)
Cancer Res
, vol.64
, pp. 4078-4081
-
-
Kim, M.1
Park, S.Y.2
Pai, H.S.3
Kim, T.H.4
Billiar, T.R.5
Seol, D.W.6
-
19
-
-
33644542405
-
The forkhead box m1 transcription factor stimulates the proliferation of tumor cells during development of lung cancer
-
Kim IM, Ackerson T, Ramakrishna S, Tretiakova M, Wang IC, Kalin TV, Major ML, Gusarova GA, Yoder HM, Costa RH, Kalinichenko VV. 2006. The forkhead box m1 transcription factor stimulates the proliferation of tumor cells during development of lung cancer. Cancer Res 66:2153-2161.
-
(2006)
Cancer Res
, vol.66
, pp. 2153-2161
-
-
Kim, I.M.1
Ackerson, T.2
Ramakrishna, S.3
Tretiakova, M.4
Wang, I.C.5
Kalin, T.V.6
Major, M.L.7
Gusarova, G.A.8
Yoder, H.M.9
Costa, R.H.10
Kalinichenko, V.V.11
-
20
-
-
13944274222
-
FoxM1 is required for execution of the mitotic programme and chromosome stability
-
Laoukili J, Kooistra MR, Bras A, Petrovic V, Major ML, Park HJ, Tan Y, Ackerson T, Costa RH. 2005. FoxM1 is required for execution of the mitotic programme and chromosome stability. Nat Cell Biol 7:126-136.
-
(2005)
Nat Cell Biol
, vol.7
, pp. 126-136
-
-
Laoukili, J.1
Kooistra, M.R.2
Bras, A.3
Petrovic, V.4
Major, M.L.5
Park, H.J.6
Tan, Y.7
Ackerson, T.8
Costa, R.H.9
-
21
-
-
33645734725
-
FoxM1B is overexpressed in human glioblastomas and critically regulates the tumorigenicity of glioma cells
-
Liu M, Dai B, Kang SH, Ban K, Huang FJ, Lang FF, Aldape KD, Xie TX, Pelloski CE, Xie K, Sawaya R, Huang S. 2006. FoxM1B is overexpressed in human glioblastomas and critically regulates the tumorigenicity of glioma cells. Cancer Res 66:3593-3602.
-
(2006)
Cancer Res
, vol.66
, pp. 3593-3602
-
-
Liu, M.1
Dai, B.2
Kang, S.H.3
Ban, K.4
Huang, F.J.5
Lang, F.F.6
Aldape, K.D.7
Xie, T.X.8
Pelloski, C.E.9
Xie, K.10
Sawaya, R.11
Huang, S.12
-
22
-
-
0035887011
-
FIH-1: A novel protein that interacts with HIF-1alpha and VHL to mediate repression of HIF-1 transcriptional activity
-
Mahon PC, Hirota K, Semenza GL. 2001. FIH-1: A novel protein that interacts with HIF-1alpha and VHL to mediate repression of HIF-1 transcriptional activity. Genes Dev 15:2675-2686.
-
(2001)
Genes Dev
, vol.15
, pp. 2675-2686
-
-
Mahon, P.C.1
Hirota, K.2
Semenza, G.L.3
-
23
-
-
34347265260
-
Transcriptional up-regulation of inhibitory PAS domain protein gene expression by hypoxia-inducible factor 1 (HIF-1): A negative feedback regulatory circuit in HIF-1-mediated signaling in hypoxic cells
-
Makino Y, Uenishi R, Okamoto K, Isoe T, Hosono O, Tanaka H, Kanopka A, Poellinger L, Haneda M, Morimoto C. 2007. Transcriptional up-regulation of inhibitory PAS domain protein gene expression by hypoxia-inducible factor 1 (HIF-1): A negative feedback regulatory circuit in HIF-1-mediated signaling in hypoxic cells. J Biol Chem 282:14073-14082.
-
(2007)
J Biol Chem
, vol.282
, pp. 14073-14082
-
-
Makino, Y.1
Uenishi, R.2
Okamoto, K.3
Isoe, T.4
Hosono, O.5
Tanaka, H.6
Kanopka, A.7
Poellinger, L.8
Haneda, M.9
Morimoto, C.10
-
24
-
-
0032079679
-
Structural changes in the region directly adjacent to the DNA binding helix highlight a possible mechanism to explain the observed changes in the sequence-specific binding of winged helix proteins
-
Marsden I, Jin C, Liao X. 1998. Structural changes in the region directly adjacent to the DNA binding helix highlight a possible mechanism to explain the observed changes in the sequence-specific binding of winged helix proteins. J Mol Biol 278:293-299.
-
(1998)
J Mol Biol
, vol.278
, pp. 293-299
-
-
Marsden, I.1
Jin, C.2
Liao, X.3
-
25
-
-
0035266345
-
Genome-wide analysis of gene expression in human hepatocellular carcinomas using cDNA microarray: Identification of genes involved in viral carcinogenesis and tumor progression
-
Okabe H, Satoh S, Kato T, Kitahara O, Yanagawa R, Yamaoka Y, Tsunoda T, Furukawa Y, Nakamura Y. 2001. Genome-wide analysis of gene expression in human hepatocellular carcinomas using cDNA microarray: Identification of genes involved in viral carcinogenesis and tumor progression. Cancer Res 61:2129-2137.
-
(2001)
Cancer Res
, vol.61
, pp. 2129-2137
-
-
Okabe, H.1
Satoh, S.2
Kato, T.3
Kitahara, O.4
Yanagawa, R.5
Yamaoka, Y.6
Tsunoda, T.7
Furukawa, Y.8
Nakamura, Y.9
-
26
-
-
0034680102
-
Molecular portraits of human breast tumors
-
Perou CM, Sorlie T, Eisen MB, van de Rijn M, Jeffrey SS, Rees CA, Pollack JR, Ross DT, Johnsen H, Aksien LA, Fluge O, Pergamenschikov A, Williams C, Zhu SX, Lonning PE, Borresen-Dale AL, Brown PO, Botstein D. 2000. Molecular portraits of human breast tumors. Nature 406:747-752.
-
(2000)
Nature
, vol.406
, pp. 747-752
-
-
Perou, C.M.1
Sorlie, T.2
Eisen, M.B.3
van de Rijn, M.4
Jeffrey, S.S.5
Rees, C.A.6
Pollack, J.R.7
Ross, D.T.8
Johnsen, H.9
Aksien, L.A.10
Fluge, O.11
Pergamenschikov, A.12
Williams, C.13
Zhu, S.X.14
Lonning, P.E.15
Borresen-Dale, A.L.16
Brown, P.O.17
Botstein, D.18
-
27
-
-
11144280578
-
Identification and validation of commonly overexpressed genes in solid tumors by comparison of microarray data
-
Pilarsky C, Wenzig M, Specht T, Saeger HD, Grutzmann R. 2004. Identification and validation of commonly overexpressed genes in solid tumors by comparison of microarray data. Neoplasia 6:744-750.
-
(2004)
Neoplasia
, vol.6
, pp. 744-750
-
-
Pilarsky, C.1
Wenzig, M.2
Specht, T.3
Saeger, H.D.4
Grutzmann, R.5
-
28
-
-
0034703017
-
Age-dependent defect in vascular endothelial growth factor expression is associated with reduced hypoxia-inducible factor 1 activity
-
Rivard A, Berthou-Soulie L, Principe N, Kearney M, Curry C, Branellec D, Semenza GL, Isner JM. 2000. Age-dependent defect in vascular endothelial growth factor expression is associated with reduced hypoxia-inducible factor 1 activity. J Biol Chem 275:29643-29647.
-
(2000)
J Biol Chem
, vol.275
, pp. 29643-29647
-
-
Rivard, A.1
Berthou-Soulie, L.2
Principe, N.3
Kearney, M.4
Curry, C.5
Branellec, D.6
Semenza, G.L.7
Isner, J.M.8
-
29
-
-
0034006016
-
HIF-1: Mediator of physiological and pathophysiological responses to hypoxia
-
Semenza GL. 2000. HIF-1: Mediator of physiological and pathophysiological responses to hypoxia. J Appl Physiol 88:1474-1480.
-
(2000)
J Appl Physiol
, vol.88
, pp. 1474-1480
-
-
Semenza, G.L.1
-
30
-
-
0028352434
-
The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA
-
Waga S, Hannon GJ, Beach D, Stillman B. 1994. The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA. Nature 369:574-578.
-
(1994)
Nature
, vol.369
, pp. 574-578
-
-
Waga, S.1
Hannon, G.J.2
Beach, D.3
Stillman, B.4
-
31
-
-
0028816847
-
Purification and characterization of hypoxia-inducible factor 1
-
Wang GL, Semenza GL. 1995. Purification and characterization of hypoxia-inducible factor 1. J Biol Chem 270:1230-1237.
-
(1995)
J Biol Chem
, vol.270
, pp. 1230-1237
-
-
Wang, G.L.1
Semenza, G.L.2
-
32
-
-
0029051439
-
Hypoxia inducible factor-1 is a basic-helix-loop-helix-pas heterodimer regulated by cellular O2 tension
-
Wang GL, Jiang BH, Rue EA, Semenza GL. 1995. Hypoxia inducible factor-1 is a basic-helix-loop-helix-pas heterodimer regulated by cellular O2 tension. Proc Natl Acad Sci USA 92:5510-5514.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 5510-5514
-
-
Wang, G.L.1
Jiang, B.H.2
Rue, E.A.3
Semenza, G.L.4
-
33
-
-
0037168526
-
The forkhead box m1b transcription factor is essential for hepatocyte DNA replication and mitosis during mouse liver regeneration
-
Wang X, Kiyokawa H, Dennewitz MB, Costa RH. 2002a. The forkhead box m1b transcription factor is essential for hepatocyte DNA replication and mitosis during mouse liver regeneration. Proc Natl Acad Sci USA 99:16881-16886.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 16881-16886
-
-
Wang, X.1
Kiyokawa, H.2
Dennewitz, M.B.3
Costa, R.H.4
-
34
-
-
0037113939
-
Increased hepatic forkhead box M1B (FoxM1B) levels in old-aged mice stimulated liver regeneration through diminished p27Kip1 protein levels and increased Cdc25B expression
-
Wang X, Krupczak-Hollis K, Tan Y, Dennewitz MB, Adami GR, Costa RH. 2002b. Increased hepatic forkhead box M1B (FoxM1B) levels in old-aged mice stimulated liver regeneration through diminished p27Kip1 protein levels and increased Cdc25B expression. J Biol Chem 277:44310-44316.
-
(2002)
J Biol Chem
, vol.277
, pp. 44310-44316
-
-
Wang, X.1
Krupczak-Hollis, K.2
Tan, Y.3
Dennewitz, M.B.4
Adami, G.R.5
Costa, R.H.6
-
35
-
-
28544449224
-
Forkhead box M1 regulates the transcriptional network of genes essential for mitotic progression and genes encoding the SCF (Skp2-1) ubiquitin ligase
-
Wang IC, Chen YJ, Hughes D, Petrovic V, Major ML, Park HJ, Tan Y, Ackerson T, Costa RH. 2005. Forkhead box M1 regulates the transcriptional network of genes essential for mitotic progression and genes encoding the SCF (Skp2-1) ubiquitin ligase. Mol Cell Biol 25:10875-10894.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 10875-10894
-
-
Wang, I.C.1
Chen, Y.J.2
Hughes, D.3
Petrovic, V.4
Major, M.L.5
Park, H.J.6
Tan, Y.7
Ackerson, T.8
Costa, R.H.9
-
36
-
-
20444477535
-
Loss of the forkhead transcription factor FoxM1 causes centrosome amplification and mitotic catastrophe
-
Wonsey DR, Follettie MT. 2005. Loss of the forkhead transcription factor FoxM1 causes centrosome amplification and mitotic catastrophe. Cancer Res 65:5181-5189.
-
(2005)
Cancer Res
, vol.65
, pp. 5181-5189
-
-
Wonsey, D.R.1
Follettie, M.T.2
-
37
-
-
0030741972
-
Molecular analysis of a novel winged helix protein, WIN. Expression pattern, DNA binding property, and alternative splicing within the DNA binding domain
-
Yao KM, Sha M, Lu Z, Wong GG. 1997. Molecular analysis of a novel winged helix protein, WIN. Expression pattern, DNA binding property, and alternative splicing within the DNA binding domain. J Biol Chem 272:19827-19836.
-
(1997)
J Biol Chem
, vol.272
, pp. 19827-19836
-
-
Yao, K.M.1
Sha, M.2
Lu, Z.3
Wong, G.G.4
-
38
-
-
0033506486
-
Premature expression of the winged helix transcription factor HFH-11B in regenerating mouse liver accelerates hepatocyte entry into S-phase
-
Ye H, Holterman A, Yoo KW, Franks RR, Costa RH. 1999. Premature expression of the winged helix transcription factor HFH-11B in regenerating mouse liver accelerates hepatocyte entry into S-phase. Mol Cell Biol 19:8570-8580.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 8570-8580
-
-
Ye, H.1
Holterman, A.2
Yoo, K.W.3
Franks, R.R.4
Costa, R.H.5
-
39
-
-
0037414180
-
YC-1: A potential anticancer drug targeting hypoxia-inducible factor 1
-
Yeo EJ, Chun YS, Cho YS, Kim J, Lee JC, Kim MS, Park JW. 2003. YC-1: A potential anticancer drug targeting hypoxia-inducible factor 1. J Natl Cancer Inst 95:516-525.
-
(2003)
J Natl Cancer Inst
, vol.95
, pp. 516-525
-
-
Yeo, E.J.1
Chun, Y.S.2
Cho, Y.S.3
Kim, J.4
Lee, J.C.5
Kim, M.S.6
Park, J.W.7
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