Burn injury induces gelsolin expression and cleavage in the brain of mice

Neuroscience

Volumn 228, Issue , 2013, Pages 60-72

  Zhang, Qing hong ^a   Li, Jun cong ^b   Dong, Ning ^a   Tang, Lu ming ^c   Zhu, Xiao mei ^a   Sheng, Zhi yong ^a   Yao, Yong ming ^a  

^a CHINESE PLA GENERAL HOSPITAL   (China)

^b THE FIRST AFFILIATED HOSPITAL OF WENZHOU MEDICAL UNIVERSITY   (China)

^c THE SECOND AFFILIATED HOSPITAL AND YUYING CHILDREN S HOSPITAL OF WENZHOU MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Burns; Caspase 3; Gelsolin; Lipopolysaccharide; Septic encephalopathy

Indexed keywords

CASPASE 3; EOSIN; GELSOLIN; HEMATOXYLIN; LIPOPOLYSACCHARIDE; MESSENGER RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN ABSCESS; BRAIN CORTEX; BRAIN DISEASE; BRAIN NECROSIS; BURN; CELL ACTIVATION; CONTROLLED STUDY; CORPUS STRIATUM; ENZYME ACTIVITY; GLIOSIS; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; MACROPHAGE; MALE; MONOCYTE; MOUSE; NERVE CELL LESION; NEUROPATHOLOGY; NEUTROPHIL CHEMOTAXIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PHEOCHROMOCYTOMA CELL; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; QUANTITATIVE ANALYSIS; RAT; SEPTIC ENCEPHALOPATHY; UPREGULATION; WESTERN BLOTTING;

ANIMALS; ASTROCYTES; BRAIN; BURNS; GELSOLIN; GENE EXPRESSION REGULATION; INFLAMMATION MEDIATORS; MALE; MICE; MICE, INBRED BALB C; NEURONS; PC12 CELLS; RANDOM ALLOCATION; RATS;

EID: 84868552706     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2012.10.013     Document Type: Article

References (39)

1. Antequera D., Vargas T., Ugalde C., Spuch C., Molina J.A., Ferrer I., et al. Cytoplasmic gelsolin increases mitochondrial activity and reduces Abeta burden in a mouse model of Alzheimer's disease. Neurobiol Dis 2009, 36:42-50.
2. Barbizan R., Oliveira A.L. Impact of acute inflammation on spinal motoneuron synaptic plasticity following ventral root avulsion. J Neuroinflammation 2010, 7:29.
3. Bozza F.A., Garteiser P., Oliveira M.F., Doblas S., Cranford R., Saunders D., et al. Sepsis-associated encephalopathy: a magnetic resonance imaging and spectroscopy study. J Cereb Blood Flow Metab 2010, 30:440-448.
4. Defaux A., Zurich M.G., Braissant O., Honegger P., Monnet-Tschudi F. Effects of the PPAR-beta agonist GW501516 in an in vitro model of brain inflammation and antibody-induced demyelination. J Neuroinflammation 2009, 6:15.
5. Dong J.H., Ying G.X., Liu X., Wang W.Y., Wang Y., Ni Z.M., et al. Lesion-induced gelsolin upregulation in the hippocampus following entorhinal deafferentation. Hippocampus 2006, 16:91-100.
6. Endres M., Fink K., Zhu J., Stagliano N.E., Bondada V., Geddes J.W., et al. Neuroprotective effects of gelsolin during murine stroke. J Clin Invest 1999, 103:347-354.
7. Flierl M.A., Rittirsch D., Huber-Lang M.S., Stahel P.F. Pathophysiology of septic encephalopathy - an unsolved puzzle. Crit Care 2010, 14:165.
8. Flierl M.A., Stahel P.F., Touban B.M., Beauchamp K.M., Morgan S.J., Smith W.R., et al. Bench-to-bedside review: burn-induced cerebral inflammation - a neglected entity?. Crit Care 2009, 13:215.
9. Goncalves A.F., Dias N.G., Moransard M., Correia R., Pereira J.A., Witke W., et al. Gelsolin is required for macrophage recruitment during remyelination of the peripheral nervous system. Glia 2010, 58:706-715.
10. Hara H., Kataoka S., Anan M., Ueda A., Mutoh T., Tabira T. The therapeutic effects of the herbal medicine, Juzen-taiho-to, on amyloid-beta burden in a mouse model of Alzheimer's disease. J Alzheimers Dis 2010, 20:427-439.
11. Ji L., Chauhan A., Chauhan V. Cytoplasmic gelsolin in pheochromocytoma-12 cells forms a complex with amyloid beta-protein. Neuroreport 2008, 19:463-466.
12. Ji L., Chauhan A., Chauhan V. Upregulation of cytoplasmic gelsolin, an amyloid-beta-binding protein, under oxidative stress conditions: involvement of protein kinase C. J Alzheimers Dis 2010, 19:829-838.
13. Ji L., Chauhan A., Muthaiyah B., Wegiel J., Chauhan V. Gelsolin levels are increased in the brain as a function of age during normal development in children that are further increased in down syndrome. Alzheimer Dis Assoc Disord 2009, 23:319-322.
14. Ji L., Chauhan A., Wegiel J., Essa M.M., Chauhan V. Gelsolin is proteolytically cleaved in the brains of individuals with Alzheimer's disease. J Alzheimers Dis 2009, 18:105-111.
15. Jordan J.R., Moore E.E., Damle S.S., Eckels P., Johnson J.L., Roach J.P., et al. Gelsolin is depleted in post-shock mesenteric lymph. J Surg Res 2007, 143:130-135.
16. Kafa I.M.U.M., Bakirci S., Ayberk Kurt M. Sepsis induces apoptotic cell death in different regions of the brain in a rat model of sepsis. Acta Neurobiol Exp (Wars) 2010, 70:14.
17. Kothakota S., Azuma T., Reinhard C., Klippel A., Tang J., Chu K., et al. Caspase-3-generated fragment of gelsolin: effector of morphological change in apoptosis. Science 1997, 278:294-298.
18. Koya R.C., Fujita H., Shimizu S., Ohtsu M., Takimoto M., Tsujimoto Y., et al. Gelsolin inhibits apoptosis by blocking mitochondrial membrane potential loss and cytochrome c release. J Biol Chem 2000, 275:15343-15349.
19. Kronenberg G., Gertz K., Baldinger T., Kirste I., Eckart S., Yildirim F., et al. Impact of actin filament stabilization on adult hippocampal and olfactory bulb neurogenesis. J Neurosci 2010, 30:3419-3431.
20. Kulakowska A., Ciccarelli N.J., Wen Q., Mroczko B., Drozdowski W., Szmitkowski M., et al. Hypogelsolinemia, a disorder of the extracellular actin scavenger system, in patients with multiple sclerosis. BMC Neurol 2010, 10:107.
21. Kulakowska A., Drozdowski W., Sadzynski A., Bucki R., Janmey P.A. Gelsolin concentration in cerebrospinal fluid from patients with multiple sclerosis and other neurological disorders. Eur J Neurol 2008, 15:584-588.
22. Lee P.S., Patel S.R., Christiani D.C., Bajwa E., Stossel T.P., Waxman A.B. Plasma gelsolin depletion and circulating actin in sepsis: a pilot study. PLoS One 2008, 3:e3712.
23. Liu X.R., Zheng X.F., Ji S.Z., Lv Y.H., Zheng D.Y., Xia Z.F., et al. Metabolomic analysis of thermally injured and/or septic rats. Burns 2010, 36:992-998.
24. Livak K.J., Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 2001, 25:402-408.
25. Matsumoto N., Kitayama H., Kitada M., Kimura K., Noda M., Ide C. Isolation of a set of genes expressed in the choroid plexus of the mouse using suppression subtractive hybridization. Neuroscience 2003, 117:405-415.
26. Ohnishi M., Matsumoto T., Nagashio R., Kageyama T., Utsuki S., Oka H., et al. Proteomics of tumor-specific proteins in cerebrospinal fluid of patients with astrocytoma: usefulness of gelsolin protein. Pathol Int 2009, 59:797-803.
27. Oikonomou N., Thanasopoulou A., Tzouvelekis A., Harokopos V., Paparountas T., Nikitopoulou I., et al. Gelsolin expression is necessary for the development of modelled pulmonary inflammation and fibrosis. Thorax 2009, 64:467-475.
28. Qiao H., Koya R.C., Nakagawa K., Tanaka H., Fujita H., Takimoto M., et al. Inhibition of Alzheimer's amyloid-beta peptide-induced reduction of mitochondrial membrane potential and neurotoxicity by gelsolin. Neurobiol Aging 2005, 26:849-855.
29. Semmler A., Hermann S., Mormann F., Weberpals M., Paxian S.A., Okulla T., et al. Sepsis causes neuroinflammation and concomitant decrease of cerebral metabolism. J Neuroinflammation 2008, 5:38.
30. Sharifi A.M., Hoda F.E., Noor A.M. Studying the effect of LPS on cytotoxicity and apoptosis in PC12 neuronal cells: role of Bax, Bcl-2, and caspase-3 protein expression. Toxicol Mech Methods 2010, 20:316-320.
31. Silacci P., Mazzolai L., Gauci C., Stergiopulos N., Yin H.L., Hayoz D. Gelsolin superfamily proteins: key regulators of cellular functions. Cell Mol Life Sci 2004, 61:2614-2623.
32. Tanaka J., Kira M., Sobue K. Gelsolin is localized in neuronal growth cones. Brain Res Dev Brain Res 1993, 76:268-271.
33. Tanaka J., Sobue K. Localization and characterization of gelsolin in nervous tissues: gelsolin is specifically enriched in myelin-forming cells. J Neurosci 1994, 14:1038-1052.
34. Van Den Boogaard M., Ramakers B.P., van Alfen N., van der Werf S.P., Fick W.F., Hoedemaekers C.W., et al. Endotoxemia-induced inflammation and the effect on the human brain. Crit Care 2010, 14:R81.
35. Vargas T., Antequera D., Ugalde C., Spuch C., Carro E. Gelsolin restores A beta-induced alterations in choroid plexus epithelium. J Biomed Biotechnol 2010, 2010:805405.
36. Witke W., Sharpe A.H., Hartwig J.H., Azuma T., Stossel T.P., Kwiatkowski D.J. Hemostatic, inflammatory, and fibroblast responses are blunted in mice lacking gelsolin. Cell 1995, 81:41-51.
37. Yildirim F., Gertz K., Kronenberg G., Harms C., Fink K.B., Meisel A., et al. Inhibition of histone deacetylation protects wild-type but not gelsolin-deficient mice from ischemic brain injury. Exp Neurol 2008, 210:531-542.
38. Yuan X., Desiderio D.M. Proteomics analysis of phosphotyrosyl-proteins in human lumbar cerebrospinal fluid. J Proteome Res 2003, 2:476-487.
39. Zhang J., Sio S.W., Moochhala S., Bhatia M. Role of hydrogen sulfide in severe burn injury-induced inflammation in mice. Mol Med 2010, 16:417-424.