Lesion-induced gelsolin upregulation in the hippocampus following entorhinal deafferentation

Hippocampus

Volumn 16, Issue 1, 2006, Pages 91-100

  Dong, Jing Hui ^a   Ying, Guo Xin ^a   Liu, Xin ^a   Wang, Wen Yuan ^a   Wang, Yan ^a   Ni, Zi Mei ^a   Zhou, Chang Fu ^a  

^a UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

Astrocyte; Deafferentation; Entorhinal cortex lesion; Glial activation; Microglia

Indexed keywords

ACTIN; ACTIN BINDING PROTEIN; CD11B ANTIGEN; CELL MARKER; GELSOLIN; GLIAL FIBRILLARY ACIDIC PROTEIN; MESSENGER RNA;

ACTIN FILAMENT; ANIMAL CELL; ARTICLE; ASTROCYTE; BRAIN DAMAGE; CELL ACTIVATION; CELL MOTILITY; CONTROLLED STUDY; DEAFFERENTATION; DENERVATION; DENTATE GYRUS; ENTORHINAL CORTEX; FEMALE; GLIA CELL; GRIFFONIA; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MICROGLIA; NERVE TRANSECTION; NONHUMAN; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SENSORY NERVE; UPREGULATION; ANIMAL; GENETICS; HISTOLOGY; METABOLISM; MOUSE; SPRAGUE DAWLEY RAT;

AFFERENT PATHWAYS; ANIMALS; ENTORHINAL CORTEX; FEMALE; GELSOLIN; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MICE; RATS; RATS, SPRAGUE-DAWLEY; UP-REGULATION;

EID: 33644861592     PISSN: 10509631     EISSN: 10981063     Source Type: Journal    
DOI: 10.1002/hipo.20134     Document Type: Article

References (65)

1. Amaral DG, Witter MP. 1989. The three dimensional organization of the hippocampal formation: a review of anatomical data. Neuroscience 31:571-591.
2. Arcaro A. 1998. The small GTP-binding protein Rac promotes the dissociation of gelsolin from actin filaments in neutrophils. J Biol Chem 273:805-813.
3. Arora PD, McCulloch CA. 1996. Dependence of fibroblast migration on actin severing activity of gelsolin. J Biol Chem 271:20516-20523.
4. Arora PD, Glogauer M, Kapus A, Kwiatkowski DJ, McCulloch CA. 2004. Gelsolin mediates collagen phagocytosis through a rac-dependent step. Mol Biol Cell 15:588-599.
5. Azuma T, Witke W, Stossel TP, Hartwig JH, Kwiatkowski DJ. 1998. Gelsolin is a downstream effector of rac for fibroblast motility. EMBO J 17: 1362-1370.
6. Batchelor PE, Liberatore GT, Wong JY, Porritt MJ, Frerichs F, Donnan GA, Howells DW. 1999. Activated macrophages and microglia induce dopaminergic sprouting in the injured striatum and express brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor. J Neurosci 19:1708-1716.
7. Bechmann I, Nitsch R. 1997a. Astrocytes and microglial cells incorporate degenerating fibers following entorhinal lesion: a light, confocal, and electron microscopical study using a phagocytosis-dependent labeling technique. Glia 20:145-154.
8. Bechmann I, Nitsch R. 1997b. Identification of phagocytic glial cells after lesion-induced anterograde degeneration using double-fluorescence labeling: combination of axonal tracing and lectin or immunostaining. Histochem Cell Biol 107:391-397.
9. Bechmann I, Nitsch R. 2000. Involvement of non-neuronal cells in entorhinal-hippocampal reorganization following lesions. Ann N Y Acad Sci 911:192-206.
10. Cadelli DS, Bandtlow CE, Schwab ME. 1992. Oligodendrocyte- and myelin-associated inhibitors of neurite outgrowth: their involvement in the lack of CNS regeneration. Exp Neurol 115:189-192.
11. Chaponnier C, Yin HL, Stossel TP. 1987. Reversibility of gelsolin/actin interaction in macrophages. Evidence of Ca2+-dependent and Ca2+-independent pathways. J Exp Med 165:97-106.
12. Chen P, Murphy-Ullrich JE, Wells A. 1996. A role for gelsolin in actuating epidermal growth factor receptor-mediated cell motility. J Cell Biol 134:689-698.
13. Chomczynski P, Sacchi N. 1987. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156-159.
14. Coppolino MG, Krause M, Hagendorff P, Monner DA, Trimble W, Grinstein S, Wehland J, Sechi AS. 2001. Evidence for a molecular complex consisting of Fyb/SLAP, SLP-76, Nck, VASP and WASP that links the actin cytoskeleton to Fcgamma receptor signaling during phagocytosis. J Cell Sci 114:4307-4318.
15. Cunningham CC, Stossel TP, Kwiatkowski DJ. 1991. Enhanced motility in NIH 3T3 fibroblasts that overexpress gelsolin. Science 251: 1233-1236.
16. Deller T, Frotscher M. 1997. Lesion-induced plasticity of central neurons: sprouting of single fibres in the rat hippocampus after unilateral entorhinal cortex lesion. Prog Neurobiol 53:687-727.
17. Dong JH, Ying GX, Zhou CF. 2004. Entorhinal deafferentation induces the expression of profilin mRNA in the reactive microglial cells in the hippocampus. Glia 47:102-108.
18. Elkabes S, DiCicco-Bloom EM, Black IB. 1996. Brain microglia/macrophages express neurotrophins that selectively regulate microglial proliferation and function. J Neurosci 16:2508-2521.
19. Fagan AM, Gage FH. 1990. Chrolinergic sprouting in the hippocampus: a proposed role for IL-1. Exp Neurol 110:105-120.
20. Fagan AM, Gage FH. 1994. Mechanisms of sprouting in the adult central nervous system: cellular responses in areas of terminal degeneration and reinnervation in the rat hippocampus. Neuroscience 58:705-725.
21. Furnish EJ, Zhou W, Cunningham CC, Kas JA, Schmidt CE. 2001. Gelsolin overexpression enhances neurite outgrowth in PC12 cells. FEBS Lett 508:282-286.
22. Gall C, Rose G, Lynch G. 1979. Proliferative and migratory activity of glial cells in the partially deafferented hippocampus. J Comp Neurol 183:539-550.
23. Gehrmann J, Schoen SW, Kreutzberg GW. 1991. Lesion of the rat entorhinal cortex leads to a rapid microglial reaction in the dentate gyrus. A light and electron microscopical study. Acta Neuropath 82:442-455.
24. Hailer NP, Grampp A, Nitsch R. 1999. Proliferation of microglia and astrocytes in the dentate gyrus following entorhinal cortex lesion: a quantitative bromodeoxyuridine-labelling study. Eur J Neurosci 11:3359-3364.
25. Hanisch UK. 2002. Microglia as a source and target of cytokines. Glia 40:140-155.
26. Hartwig JH, Chambers KA, Stossel TP. 1989. Association of gelsolin with actin filaments and cell membranes of macrophages and platelets. J Cell Biol 108:467-479.
27. Hartwig JH, Bokoch GM, Carpenter CL, Janmey PA, Taylor LA, Toker A, Stossel TP. 1995. Thrombin receptor ligation and activated Rac uncap actin filament barbed ends through phosphoinositide synthesis in permeabilized human platelets. Cell 82:643-653.
28. Hollerbach EH, Haas CA, Hilderbandt H, Frotscher M, Naumann T. 1998. Region-specific activation of microglial cells in the rat septal complex following fimbria-fornix transection. J Comp Neurol 390: 481-496.
29. Howard T, Chaponnier C, Yin H, Stossel T. 1990. Gelsolin-actin interaction and actin polymerization in human neutrophils. J Cell Biol 110:1983-1991.
30. Janmey PA, Stossel TP. 1987. Modulation of gelsolin function by phosphatidylinositol 4,5-bisphosphate. Nature 325:362-364.
31. Jensen MB, Gonzalez B, Castellano B, Zimmer J. 1994. Microglial and astroglial reactions to anterograde axonal degeneration: a histochemical and immunocytochemical study of the adult rat fascia dentata after entorhinal perforant path lesions. Exp Brain Res 98: 245-260.
32. Jensen MB, Finsen B, Zimmer J. 1997. Morphological and immunophenotypic microglial changes in the denervated fascia dentata of adult rats: correlation with blood-brain barrier damage and astroglial reactions. Exp Neurol 143:103-116.
33. Kreutzberg GW. 1996. Microglia: a sensor for pathological events in the CNS. Trends Neurosci 19:312-318.
34. Kwiatkowski DJ. 1999. Functions of gelsolin: motility, signaling, apoptosis, cancer. Curr Opin Cell Biol 11:103-108.
35. Lamb JA, Allen PG, Tuan BY, Janmey PA. 1993. Modulation of gelsolin function. Activation at low pH overrides Ca2+ requirement. J Biol Chem 268:8999-9004.
36. Lee KS, Stanford EJ, Cotman CW, Lynch GS. 1977. Ultrastructural evidence for bouton proliferation in the partially deafferented dentate gyrus of the adult rat. Exp Brain Res 29:475-485.
37. Lind SE, Janmey PA, Chaponnier C, Herbert TJ, Stossel TP. 1987. Reversible binding of actin to gelsolin and profilin in human platelet extracts. J Cell Biol 105:833-842.
38. Lu M, Witke W, Kwiatkowski DJ, Kosik KS. 1997. Delayed retraction of filopodia in gelsolin null mice. J Cell Biol 138:1279-1287.
39. Lynch G, Matthews DA, Mosko S, Parks T, Cotman C. 1972. Induced acetylcholinesterase-rich layer in rat dentate gyrus following entorhinal lesions. Brain Res 42:311-318.
40. Matthews DA, Cotman C, Lynch G. 1976a. An electron microscopic study of lesion-induced synaptogenesis in the dentate gyrus of the adult rat. I. Magnitude and time course of degeneration Brain Res 115: 1-21.
41. Matthews DA, Cotman C, Lynch G. 1976b. An electron microscopic study of lesion-induced synaptogenesis in the dentate gyrus of the adult rat. II. Reappearance of morphologically normal synaptic contacts Brain Res 115:23-41.
42. Rose G, Lynch G, Cotman CW. 1976. Hypertrophy and redistribution of astrocytes in the deafferented dentate gyrus. Brain Res Bull 1:87-92.
43. Roth LW, Bormann P, Wiederkehr C, Reinhard E. 1999. Beta-thymosin, a modulator of the actin cytoskeleton is increased in regenerating retinal ganglion cells. Eur J Neurosci 11:3488-98.
44. Savaskan NE, Plaschke M, Ninnemann O, Spillmann AA, Schwab ME, Nitsch R, Skutella T. 1999. Myelin does not influence the choice behaviour of entorhinal axons but strongly inhibits their outgrowth length in vitro. Eur J Neurosci 11:316-326.
45. Schnell L, Schwab ME. 1990. Axonal regeneration in the rat spinal cord produced by an antibody against myelin-associated neurite growth inhibitors. Nature 343:269-272.
46. Serrander L, Skarman P, Rasmussen B, Witke W, Lew DP, Krause KH, Stendahl O, Nusse O. 2000. Selective inhibition of IgG-mediated phagocytosis in gelsolin-deficient murine neutrophils. J Immunol 165:2451-2457.
47. Steward O. 1992a. Lesion-induced synapse reorganization in the hippocampus of cats: sprouting of entorhinal, commissural/associational, and mossy fiber projections after unilateral entorhinal cortex lesions, with comments on the normal organization of these pathways. Hippocampus 2:247-268.
48. Steward O. 1992b. Signals that induce sprouting in the central nervous system: sprouting is delayed in a strain of mouse exhibiting delayed axonal degeneration. Exp Neurol 118:340-351.
49. Steward O, Cotman C, Lynch G. 1976. A quantitative autoradiographic and electrophysiological study of the reinnervation of the dentate gyrus by contralateral entorhinal cortex following ipsilateral entorhinal lesion. Brain Res 114:181-200.
50. Steward O, Kelley MS, Torre ER. 1993.The process of reinnervation in the dentate gyrus of adult rats: temporal relationship between changes in the levels of glial fibrillary acidic protein (GFAP) and GFAP mRNA in reactive astrocytes.
51. Streit WJ. 1990. An improved staining method for rat microglial cells using the lectin from Griffonia simplicifolia (GSA I-B4). J Histochem Cytochem 38:1683-1686.
52. Streit WJ, Graeber MB, Kreutzberg GW. 1988. Functional plasticity of microglia: a review. Glia 1:301-307.
53. Sun HQ, Yamamoto M, Mejillano M, Yin HL. 1999. Gelsolin, a multifunctional actin regulatory protein. J Biol Chem 47:33179-33182.
54. Tanaka J, Sobue K. 1994. Localization and characterization of gelsolin in nervous tissues: gelsolin is specifically enriched in myelin-forming cells. J Neurosci 14(Part 1):1038-1052.
55. Turner DA, Buhl EH, Hailer NP, Nitsch R. 1998. Morphological features of the entorhinal-hippocampal connection. Prog Neurobiol 55:537-562.
56. Wang Y, Zhou CF. 2005. Involvement of interferon-gamma and its receptor in the activation of astrocytes in the mouse hippocampus following entorhinal deafferentation. Glia 50:56-65.
57. Witke W, Sharpe AH, Hartwig JH, Azuma T, Stossel TP, Kwiatkowski DJ. 1995. Hemostatic, inflammatory, and fibroblast responses are blunted in mice lacking gelsolin. Cell 81:41-51.
58. Yin HL. 1987. Gelsolin: calcium- and polyphosphoinositide-regulated actin-modulating protein. Bioessays 7:176-179.
59. Yin HL, Stossel TP. 1979. Control of cytoplasmic actin gel-sol transformation by gelsolin, a calcium-dependent regulatory protein. Nature 281:583-586.
60. Yin HL, Stossel TP. 1980. Purification and structural properties of gelsolin, a Ca2+-activated regulatory protein of macrophages. J Biol Chem 255:9490-9493.
61. Yin HL, Albrecht JH, Fattoum A. 1981a. Identification of gelsolin, a Ca2+-dependent regulatory protein of actin gel-sol transformation, and its intracellular distribution in a variety of cells and tissues, J Cell Biol 91:901-906.
62. Yin HL, Hartwig JH, Maruyama K, Stossel TP. 1981b. Ca2+ control of actin filament length. Effects of macrophage gelsolin on actin polymerization. J Biol Chem 256:9693-9697.
63. Ying GX, Huang C, Jiang ZH, Liu X, Jing NH, Zhou CF. 2002. Up-regulation of cystatin C expression in the murine hippocampus following perforant path transections. Neuroscience 112:289-298.
64. Ying GX, Liu X, Wang WY, Wang Y, Dong JH, Jin HF, Huang C, Zhou CF. 2004. Regulated transcripts in the hippocampus following transections of the entorhinal afferents. Biochem Biophys Res Commun 322:210-216.
65. Zhou W, Raisman G, Zhou C. 1998. Transplanted embryonic entorhinal neurons make functional synapses in adult host hippocampus. Brain Res 788:202-206.