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Volumn 28, Issue 3, 2007, Pages 445-449

Stoichiometry and conditional stability constants of Cu(II) or Zn(II) clioquinol complexes; implications for Alzheimer's and Huntington's disease therapy

Author keywords

Alzheimer's and Hungtington's diseases; Clioquinol; Clioquinol complexes; Cu(II); Neurodegenerative diseases; Oxine; Zn(II)

Indexed keywords

ADENOSINE TRIPHOSPHATE; AMYLOID BETA PROTEIN; BUFFER; CALCIUM ION; CLIOQUINOL; CUPRIC ION; HUNTINGTIN; MAGNESIUM ION; PURINE P2X RECEPTOR; ZINC ION;

EID: 34249786569     PISSN: 0161813X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuro.2007.02.004     Document Type: Article
Times cited : (80)

References (21)
  • 3
    • 0036860349 scopus 로고    scopus 로고
    • Metal complexing agents as therapies for Alzheimer's disease
    • Bush A.I. Metal complexing agents as therapies for Alzheimer's disease. Neurobiol Aging 23 (2002) 1031
    • (2002) Neurobiol Aging , vol.23 , pp. 1031
    • Bush, A.I.1
  • 4
    • 0037386086 scopus 로고    scopus 로고
    • The metallobiology of Alzheimer's disease
    • Bush A.I. The metallobiology of Alzheimer's disease. Trends Neurosci 4 (2003) 207
    • (2003) Trends Neurosci , vol.4 , pp. 207
    • Bush, A.I.1
  • 6
    • 0032732859 scopus 로고    scopus 로고
    • Polarographic determination of half-wave potentials for copper organic complexes in sea water
    • Croot P.L., Moffett J.W., and Luther GW. Polarographic determination of half-wave potentials for copper organic complexes in sea water. Mar Chem 67 (1999) 219
    • (1999) Mar Chem , vol.67 , pp. 219
    • Croot, P.L.1    Moffett, J.W.2    Luther GW3
  • 7
    • 0011966364 scopus 로고    scopus 로고
    • Excited-state dynamics in 8-hydroxyquinoline dimers
    • Cheatum C.M., Heckscher M.M., and Crim F.F. Excited-state dynamics in 8-hydroxyquinoline dimers. Chem Phys Lett 349 (2001) 37
    • (2001) Chem Phys Lett , vol.349 , pp. 37
    • Cheatum, C.M.1    Heckscher, M.M.2    Crim, F.F.3
  • 8
    • 2942750367 scopus 로고    scopus 로고
    • Clioquinol a drug for Alzheimer's disease specifically interfering with brain metal metabolism: structural characterization of its zinc(II) and copper(II) complexes
    • Di Vaira C., Bazzicalupi C., Orioli P., Messori L., Bruni B., and Zatta P. Clioquinol a drug for Alzheimer's disease specifically interfering with brain metal metabolism: structural characterization of its zinc(II) and copper(II) complexes. Inorg Chem 43 (2004) 3795
    • (2004) Inorg Chem , vol.43 , pp. 3795
    • Di Vaira, C.1    Bazzicalupi, C.2    Orioli, P.3    Messori, L.4    Bruni, B.5    Zatta, P.6
  • 9
    • 0000569792 scopus 로고
    • Structure and behavior of organic analytical reagents. III. Stability of chelates of 8-hydroxyquinoline and analogous reagents
    • Johnston W.D., and Freiser H. Structure and behavior of organic analytical reagents. III. Stability of chelates of 8-hydroxyquinoline and analogous reagents. J Am Chem Soc 74 (1952) 5239
    • (1952) J Am Chem Soc , vol.74 , pp. 5239
    • Johnston, W.D.1    Freiser, H.2
  • 10
    • 0348100547 scopus 로고
    • Chelate stabilities of certain oxine-type compounds
    • Lane T.J., Sam C.S., and Kandathil A.J. Chelate stabilities of certain oxine-type compounds. J Am Chem Soc 82 (1960) 4462
    • (1960) J Am Chem Soc , vol.82 , pp. 4462
    • Lane, T.J.1    Sam, C.S.2    Kandathil, A.J.3
  • 11
    • 0037997162 scopus 로고    scopus 로고
    • The human prion octarepeat fragment prevents and reverses the inhibitory action of copper in the P2X4 receptor without modifying the zinc action
    • Lorca R.A., Chacon M., Barria M.I., Inestrosa N.C., and Huidobro-Toro J.P. The human prion octarepeat fragment prevents and reverses the inhibitory action of copper in the P2X4 receptor without modifying the zinc action. J Neurochem 85 (2003) 709
    • (2003) J Neurochem , vol.85 , pp. 709
    • Lorca, R.A.1    Chacon, M.2    Barria, M.I.3    Inestrosa, N.C.4    Huidobro-Toro, J.P.5
  • 12
    • 0346613553 scopus 로고    scopus 로고
    • Synthesis, crystal structure, molecular orbital calculations and electronic properties of 2,3-di(2-pyridyl)naphtho[2,3-f]quinoxaline-7,12-quinone (Aqdpp)
    • López R., Boys D., Loeb B., and Zuloaga F. Synthesis, crystal structure, molecular orbital calculations and electronic properties of 2,3-di(2-pyridyl)naphtho[2,3-f]quinoxaline-7,12-quinone (Aqdpp). J Chem Soc Perkin Trans 2 (1998) 877-883
    • (1998) J Chem Soc Perkin Trans , vol.2 , pp. 877-883
    • López, R.1    Boys, D.2    Loeb, B.3    Zuloaga, F.4
  • 14
    • 23844482456 scopus 로고    scopus 로고
    • Clioquinol down-regulates mutant huntingtin expression in vitro and mitigates pathology in a Huntington's disease mouse model
    • Nguyen T., Hamby A., and Massa S. Clioquinol down-regulates mutant huntingtin expression in vitro and mitigates pathology in a Huntington's disease mouse model. Proc Natl Acad Sci USA 102 (2005) 11840
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 11840
    • Nguyen, T.1    Hamby, A.2    Massa, S.3
  • 15
    • 10744224267 scopus 로고    scopus 로고
    • Metal-protein attenuation with iodochlorhydroxyquin (clioquinol) targeting Aβ amyloid deposition and toxicity in Alzheimer disease: a pilot phase 2 clinical trial
    • Ritchie C.W., Bush A.I., Mackinnon A., Macfarlane S., Mastwyk M., MacGregor L., et al. Metal-protein attenuation with iodochlorhydroxyquin (clioquinol) targeting Aβ amyloid deposition and toxicity in Alzheimer disease: a pilot phase 2 clinical trial. Arch Neurol 60 (2003) 1685
    • (2003) Arch Neurol , vol.60 , pp. 1685
    • Ritchie, C.W.1    Bush, A.I.2    Mackinnon, A.3    Macfarlane, S.4    Mastwyk, M.5    MacGregor, L.6
  • 18
    • 85101569542 scopus 로고    scopus 로고
    • Clioquinol's return: cautions from Japan
    • Takeshi T. Clioquinol's return: cautions from Japan. Science 292 (2001) 2251
    • (2001) Science , vol.292 , pp. 2251
    • Takeshi, T.1
  • 19
    • 10644280708 scopus 로고    scopus 로고
    • Clioquinol mediates copper uptake and counteracts copper efflux activities of the amyloid precursor protein of Alzheimer's disease
    • Treiber C., Simons A., Strauss M., Hafner M., Cappai R., Bayer T.A., et al. Clioquinol mediates copper uptake and counteracts copper efflux activities of the amyloid precursor protein of Alzheimer's disease. J Biol Chem 279 (2004) 51958
    • (2004) J Biol Chem , vol.279 , pp. 51958
    • Treiber, C.1    Simons, A.2    Strauss, M.3    Hafner, M.4    Cappai, R.5    Bayer, T.A.6
  • 21
    • 33745860362 scopus 로고    scopus 로고
    • Degradation of the alzheimer's disease amyloid beta peptide by metal-dependent up-regulation of metalloprotease activity
    • White A.R., Du T., Laughton K.M., Volitakis I., Sharples R.A., Xilinas M.E., et al. Degradation of the alzheimer's disease amyloid beta peptide by metal-dependent up-regulation of metalloprotease activity. J Biol Chem 281 (2006) 17670
    • (2006) J Biol Chem , vol.281 , pp. 17670
    • White, A.R.1    Du, T.2    Laughton, K.M.3    Volitakis, I.4    Sharples, R.A.5    Xilinas, M.E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.