Ahr2-dependence of PCB126 effects on the swim bladder in relation to expression of CYP1 and cox-2 genes in developing zebrafish

Toxicology and Applied Pharmacology

Volumn 265, Issue 2, 2012, Pages 166-174

  Jönsson, Maria E ^a,b   Kubota, Akira ^b   Timme Laragy, Alicia R ^b,c   Woodin, Bruce ^b   Stegeman, John J ^b  

^a UPPSALA UNIVERSITY   (Sweden)

^b WOODS HOLE OCEANOGRAPHIC INSTITUTION   (United States)

^c UNIVERSITY OF MASSACHUSETTS   (United States)

Author keywords

3,3',4,4',5 pentachlorobiphenyl (PCB126); Aryl hydrocarbon receptor (Ahr); Cyclooxygenase 2 (Cox 2); Cytochrome P450 1 (CYP1); Embryonic development; Swim bladder; Zebrafish

Indexed keywords

3,3',4,4',5 PENTACHLOROBIPHENYL; AROMATIC HYDROCARBON RECEPTOR; BETA CATENIN; CYCLOOXYGENASE 2; CYTOCHROME; CYTOCHROME P450 1; DIMETHYL SULFOXIDE; MESSENGER RNA; UNCLASSIFIED DRUG;

ARTICLE; BLADDER; ENZYME INHIBITION; GENE EXPRESSION; GENE SILENCING; HISTOLOGY; HISTOPATHOLOGY; LUNG DEVELOPMENT; NONHUMAN; PROMOTER REGION; PROTEIN INDUCTION; REAL TIME POLYMERASE CHAIN REACTION; SWIMMING DEVICE; TELEOST; ZEBRA FISH;

AIR SACS; ANIMALS; BETA CATENIN; CYCLOOXYGENASE 2; CYTOCHROME P-450 CYP1A1; DOSE-RESPONSE RELATIONSHIP, DRUG; EMBRYO, NONMAMMALIAN; ESTROGEN ANTAGONISTS; FEMALE; HISTOCYTOCHEMISTRY; MALE; POLYCHLORINATED BIPHENYLS; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, ARYL HYDROCARBON; RNA, MESSENGER; ZEBRAFISH; ZEBRAFISH PROTEINS;

DANIO RERIO; TELEOSTEI; TETRAPODA;

EID: 84868488979     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2012.09.023     Document Type: Article

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