Development of the morpholino gene knockdown technique in Fundulus heteroclitus: A tool for studying molecular mechanisms in an established environmental model

Aquatic Toxicology

Volumn 87, Issue 4, 2008, Pages 289-295

  Matson, Cole W ^a   Clark, Bryan W ^a   Jenny, Matthew J ^b   Fleming, Carrie R ^a   Hahn, Mark E ^b   Di Giulio, Richard T ^a  

^a DUKE UNIVERSITY   (United States)

^b WOODS HOLE OCEANOGRAPHIC INSTITUTION   (United States)

Author keywords

Antisense morpholino oligonucleotide; Atlantic killifish; CYP1A; Development; Fundulus heteroclitus; Genetic toxicology; Teratogenesis

Indexed keywords

ANTISENSE MORPHOLINO OLIGONUCLEOTIDE; ANTISENSE OLIGONUCLEOTIDE; BETA NAPHTHOFLAVONE; CYTOCHROME P450 1A;

ENVIRONMENTAL MODELING; GENE EXPRESSION; GENETIC ENGINEERING; MOLECULAR ANALYSIS; TELEOST; TOXICOLOGY;

ANIMAL EMBRYO; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FUNDULUS HETEROCLITUS; GENE TECHNOLOGY; GENETIC TOXICOLOGY; GENOTOXICITY; KNOCKOUT GENE; METHODOLOGY; MOLECULAR DYNAMICS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SPECIES DIFFERENCE; TELEOST; TERATOGENICITY;

ANIMALS; BETA-NAPHTHOFLAVONE; CYTOCHROME P-450 CYP1A1; EMBRYO, NONMAMMALIAN; FUNDULIDAE; HEART DEFECTS, CONGENITAL; MODELS, BIOLOGICAL; OLIGONUCLEOTIDES, ANTISENSE;

CYPRINODONTOIDEI; DANIO RERIO; FUNDULUS; FUNDULUS HETEROCLITUS; TELEOSTEI;

EID: 42749084234     PISSN: 0166445X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.aquatox.2008.02.010     Document Type: Article

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