Adipocyte Dysfunction in a Mouse Model of Polycystic Ovary Syndrome (PCOS): Evidence of Adipocyte Hypertrophy and Tissue-Specific Inflammation

PLoS ONE

Volumn 7, Issue 10, 2012, Pages

  Marino, Joseph S ^a   Iler, Jeffrey ^a   Dowling, Abigail R ^a   Chua, Streamson ^c   Bruning, Jens C ^d   Coppari, Roberto ^e   Hill, Jennifer W ^a,b  

^a MEDICAL COLLEGE OF OHIO   (United States)

^b UNIVERSITY OF TOLEDO MEDICAL CENTER   (United States)

^c ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^d UNIVERSITY OF COLOGNE   (Germany)

^e UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; INSULIN RECEPTOR; INTERLEUKIN 1BETA; INTERLEUKIN 6; LEPTIN RECEPTOR; MESSENGER RNA;

ABDOMINAL OBESITY; ADIPOCYTE; ADIPOCYTE DYSFUNCTION; ADIPOSE TISSUE MORPHOLOGY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY COMPOSITION; BODY FAT DISTRIBUTION; CHRONIC INFLAMMATION; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DIABETES MELLITUS; ESTRUS CYCLE; FEMALE; GENE EXPRESSION; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; GLUCOSE TOLERANCE; LIPID STORAGE; MACROPHAGE FUNCTION; MACROPHAGE INFILTRATION; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; OVARIAN MORPHOLOGY; OVARY POLYCYSTIC DISEASE; OVULATION; PATHOGENESIS; PREGNANCY DIABETES MELLITUS; RISK ASSESSMENT; SOFT TISSUE INFLAMMATION; TISSUE SPECIFICITY; TISSUE STRUCTURE;

ADIPOCYTES; ADIPOSE TISSUE; ANIMALS; BLOOD GLUCOSE; DISEASE MODELS, ANIMAL; FEMALE; GENE EXPRESSION; HUMANS; HYPERTROPHY; INFLAMMATION; INTERLEUKIN-1BETA; INTERLEUKIN-6; LIVER; MAGNETIC RESONANCE IMAGING; MALE; MICE; MICE, KNOCKOUT; OVARY; OVULATION; POLYCYSTIC OVARY SYNDROME; PREGNANCY; RECEPTOR, INSULIN; RECEPTORS, LEPTIN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TOMOGRAPHY, X-RAY COMPUTED;

MUS;

EID: 84868320669     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0048643     Document Type: Article

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