Inactivation of MARK4, an AMP-activated protein kinase (AMPK)-related kinase, leads to insulin Hypersensitivity and resistance to diet-induced obesity

Journal of Biological Chemistry

Volumn 287, Issue 45, 2012, Pages 38305-38315

  Sun, Chao ^a,b   Tian, Liang ^a,b   Nie, Jia ^b,c   Zhang, Hai ^b   Han, Xiao ^c   Shi, Yuguang ^b  

^a NORTHWEST A F UNIVERSITY   (China)

^b PENN STATE COLLEGE OF MEDICINE   (United States)

^c NANJING MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

AMP-ACTIVATED PROTEIN KINASE; BIOLOGICAL FUNCTIONS; DIET-INDUCED OBESITY; ENERGY HOMEOSTASIS; KINASE FAMILY; METABOLIC RATES;

ENZYMES; GLUCOSE; MAMMALS; PHYSIOLOGY;

NUTRITION;

HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MICROTUBULE AFFINITY REGULATORY KINASE 4; PROTEIN KINASE B; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BROWN ADIPOSE TISSUE; CONTROLLED STUDY; ENERGY BALANCE; ENZYME ACTIVITY; ENZYME INACTIVATION; ENZYME PHOSPHORYLATION; GENE; GENE TARGETING; GLUCOSE HOMEOSTASIS; HYPERACTIVITY; HYPERMETABOLISM; HYPERPHAGIA; INSULIN RESISTANCE; MICROTUBULE AFFINITY REGULATORY KINASE 4 GENE; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION;

ANIMALS; BLOOD GLUCOSE; BLOTTING, WESTERN; DIABETES MELLITUS, TYPE 2; DIETARY FATS; ENERGY METABOLISM; FEMALE; GLUCOSE; HOMEOSTASIS; HYPERPHAGIA; INSULIN RESISTANCE; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; OBESITY; OXYGEN CONSUMPTION; PROTEIN-SERINE-THREONINE KINASES;

MUS; RODENTIA;

EID: 84868307422     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.388934     Document Type: Article

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