Loss of Par-1a/MARK3/C-TAK1 kinase leads to reduced adiposity, resistance to hepatic steatosis, and defective gluconeogenesis

Molecular and Cellular Biology

Volumn 30, Issue 21, 2010, Pages 5043-5056

  Lennerz, Jochen K ^a,d   Hurov, Jonathan B ^a,e   White, Lynn S ^a,c   Lewandowski, Katherine T ^a   Prior, Julie L ^a,b   Planer, G James ^a   Gereau IV, Robert W ^a   Piwnica Worms, David ^a,b   Schmidt, Robert E ^a   Piwnica Worms, Helen ^a,c  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^d MASSACHUSETTS GENERAL HOSPITAL   (United States)

^e AGIOS PHARMACEUTICALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPONECTIN; CHOLESTEROL; FATTY ACID; GLUCAGON; GLUCOSE; GLYCOGEN; GLYCOGEN SYNTHASE; INSULIN; LEPTIN; PARTITIONING DEFECTIVE PROTEIN 1A; PARTITIONING DEFECTIVE PROTEIN 1B; PROTEIN KINASE; UNCLASSIFIED DRUG; CELL CYCLE PROTEIN; FAT INTAKE; MARK2 PROTEIN, MOUSE; MARK3 PROTEIN, MOUSE; PRIMER DNA; PROTEIN SERINE THREONINE KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOPHAGY; CONTROLLED STUDY; CROSS BREEDING; DISEASE SEVERITY; EMBRYO; EMBRYO DEVELOPMENT; ENERGY EXPENDITURE; FATTY LIVER; FEMALE; GLUCONEOGENESIS; GLUCOSE INTOLERANCE; GLUCOSE METABOLISM; GLUCOSE TRANSPORT; GLYCOGEN LIVER LEVEL; GROWTH RETARDATION; HYPERMETABOLISM; HYPOGLYCEMIA; INSULIN RELEASE; INSULIN SENSITIVITY; LIPID DIET; MALE; MOUSE; NONHUMAN; OBESITY; PHENOTYPE; PRIORITY JOURNAL; SURVIVAL; WEIGHT GAIN; ADMINISTRATION AND DOSAGE; ALLELE; ANIMAL; DEFICIENCY; ENERGY METABOLISM; ENZYMOLOGY; FAT INTAKE; GENETICS; INSULIN RESISTANCE; KNOCKOUT MOUSE; NUCLEOTIDE SEQUENCE; PATHOPHYSIOLOGY; PHYSIOLOGY; PREGNANCY; STARVATION;

ANURA; MAMMALIA; MUS;

ADIPOSITY; ALLELES; ANIMALS; BASE SEQUENCE; CELL CYCLE PROTEINS; CROSSES, GENETIC; DIETARY FATS; DNA PRIMERS; EMBRYONIC DEVELOPMENT; ENERGY METABOLISM; FATTY LIVER; FEMALE; GLUCONEOGENESIS; INSULIN RESISTANCE; MALE; MICE; MICE, KNOCKOUT; OBESITY; PHENOTYPE; PREGNANCY; PROTEIN-SERINE-THREONINE KINASES; STARVATION;

EID: 77957850112     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.01472-09     Document Type: Article

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