Toll-like receptor 4 is expressed on intestinal stem cells and regulates their proliferation and apoptosis via the p53 up-regulated modulator of apoptosis

Journal of Biological Chemistry

Volumn 287, Issue 44, 2012, Pages 37296-37308

  Neal, Matthew D ^a   Sodhi, Chhinder P ^a   Jia, Hongpeng ^a   Dyer, Mitchell ^a   Egan, Charlotte E ^a   Yazji, Ibrahim ^a   Good, Misty ^a   Afrazi, Amin ^a   Marino, Ryan ^a   Slagle, Dennis ^a   Ma, Congrong ^a   Branca, Maria F ^a   Prindle, Thomas ^a   Grant, Zachary ^a   Ozolek, John ^a   Hackam, David J ^a  

^a CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL DEATH;

CELL REGULATION; P53 UP-REGULATED MODULATOR OF APOPTOSIS; PROLIFERATION AND APOPTOSIS; STEM-CELL; TOLL-LIKE RECEPTOR 4;

STEM CELLS;

CELL MARKER; LGR5 PROTEIN; MYELOID DIFFERENTIATION FACTOR 88; PUMA PROTEIN; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR ADAPTOR MOLECULE 1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN EXPRESSION; ANTIGEN FUNCTION; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; CYTOPLASM; FLOW CYTOMETRY; FLUORESCENCE IN SITU HYBRIDIZATION; IN VIVO STUDY; INTESTINAL STEM CELL; INTESTINE CELL; INTESTINE CRYPT; MOUSE; NECROTIZING ENTEROCOLITIS; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; RECEPTOR UPREGULATION; REGULATORY MECHANISM; STEM CELL;

EID: 84868261605     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.375881     Document Type: Article

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