Heparin-binding EGF-like growth factor protects intestinal stem cells from injury in a rat model of necrotizing enterocolitis

Laboratory Investigation

Volumn 92, Issue 3, 2012, Pages 331-344

  Chen, Chun Liang ^a   Yu, Xiaoyi ^a   James, Iyore O A ^a   Zhang, Hong Yi ^a   Yang, Jingyuan ^a   Radulescu, Andrei ^a   Zhou, Yu ^a   Besner, Gail E ^a  

^a THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

epithelial cells; HB EGF; intestine; LGR5; prominin 1; stem cells

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; HEPARIN BINDING EPIDERMAL GROWTH FACTOR; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE 2; PHOSPHATIDYLINOSITOL 3 KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CELL DAMAGE; CELL EXPANSION; CELL HYPOXIA; CELL LINEAGE; CELL PROTECTION; CELL SURVIVAL; CONTROLLED STUDY; EX VIVO STUDY; EXPERIMENTAL MODEL; GOBLET CELL; HOMEOSTASIS; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; INTESTINE CELL; INTESTINE CRYPT; INTESTINE MUCOSA; INTESTINE STEM CELL; INTESTINE VILLUS; NECROTIZING ENTEROCOLITIS; NEUROSECRETORY CELL; NEWBORN; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN INDUCTION; RAT; SIGNAL TRANSDUCTION; STEM CELL;

ANIMALS; ANIMALS, NEWBORN; ANOXIA; ANTIGENS, CD; CELL SURVIVAL; DISEASE MODELS, ANIMAL; DRUG EVALUATION, PRECLINICAL; ENTEROCOLITIS, NECROTIZING; ENTEROCYTES; FEMALE; GLYCOPROTEINS; GOBLET CELLS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; INTESTINES; MAP KINASE SIGNALING SYSTEM; NEUROENDOCRINE CELLS; PEPTIDES; PREGNANCY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, EPIDERMAL GROWTH FACTOR; STEM CELLS;

EID: 84863229817     PISSN: 00236837     EISSN: 15300307     Source Type: Journal    
DOI: 10.1038/labinvest.2011.167     Document Type: Article

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