Orphan nuclear receptor small heterodimer partner negatively regulates growth hormone-mediated induction of hepatic gluconeogenesis through inhibition of signal transducer and activator of transcription 5 (STAT5) transactivation

Journal of Biological Chemistry

Volumn 287, Issue 44, 2012, Pages 37098-37108

  Kim, Yong Deuk ^a,c   Li, Tiangang ^d   Ahn, Seung Won ^a   Kim, Don Kyu ^a   Lee, Ji Min ^a   Hwang, Seung Lark ^c   Kim, Yong Hoon ^e   Lee, Chul Ho ^e   Lee, In Kyu ^c   Chiang, John Y L ^d   Choi, Hueng Sik ^a,b  

^a Chonnam National University   (South Korea)

^b Chonnam National University Medical School   (South Korea)

^c Kyungpook National University School of Medicine   (South Korea)

^d Northeast Ohio Medical University   (United States)

^e Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE HOMEOSTASIS; GLUCOSE METABOLISM; GROWTH HORMONES; HEPATIC GLUCONEOGENESIS; HETERODIMERS; NUCLEAR RECEPTORS; SIGNAL TRANSDUCERS; TRANSACTIVATION;

GLUCOSE; INTERNET PROTOCOLS;

METABOLISM;

ATM PROTEIN; GLUCOSE 6 PHOSPHATASE; GROWTH HORMONE; HETERODIMER; METFORMIN; N BENZYL 2 CYANO 3 (3,4 DIHYDROXYPHENYL)ACRYLAMIDE; ORPHAN NUCLEAR RECEPTOR; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); PROTEIN TYROSINE PHOSPHATASE SHP; STAT5 PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING SITE; CONTROLLED STUDY; G6PASE GENE; GENE; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; GENE SILENCING; GLUCONEOGENESIS; GLUCOSE HOMEOSTASIS; HORMONE ACTION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; LIVER METABOLISM; MALE; METABOLIC REGULATION; MOUSE; MUTATIONAL ANALYSIS; NONHUMAN; PEPCK GENE; POINT MUTATION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS INHIBITION; SHP GENE; STAT5 GENE; TRANSACTIVATION;

ADENYLATE KINASE; ANIMALS; CELL CYCLE PROTEINS; DNA-BINDING PROTEINS; DOWN-REGULATION; ENZYME ACTIVATORS; GENES, REPORTER; GLUCONEOGENESIS; GLUCOSE-6-PHOSPHATASE; HEP G2 CELLS; HEPATOCYTES; HUMAN GROWTH HORMONE; HUMANS; LIVER; METFORMIN; MICE; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); PROMOTER REGIONS, GENETIC; PROTEIN BINDING; PROTEIN-SERINE-THREONINE KINASES; RATS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; SIGNAL TRANSDUCTION; STAT5 TRANSCRIPTION FACTOR; TRANSCRIPTIONAL ACTIVATION; TUMOR SUPPRESSOR PROTEINS;

EID: 84868249301     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.339887     Document Type: Article

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