Targeting BRCA1 localization to augment breast tumor sensitivity to poly(ADP-Ribose) polymerase inhibition

Cancer Research

Volumn 72, Issue 21, 2012, Pages 5547-5555

  Yang, Eddy S ^a,b,c   Nowsheen, Somaira ^a   Rahman, Mohammad A ^d   Cook, Rebecca S ^a   Xia, Fen ^a,d  

^a THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

^b Department of Cell Biology ^*  (United States)

^c UNIVERSITY OF ALABAMA SCHOOL OF MEDICINE   (United States)

^d VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRCA1 PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; RAD51 PROTEIN; SHORT HAIRPIN RNA; VELIPARIB;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST CANCER; CANCER GROWTH; CANCER RADIOTHERAPY; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DNA REPAIR; DOUBLE STRANDED DNA BREAK; DRUG CYTOTOXICITY; DRUG SENSITIVITY; DRUG TARGETING; ENZYME INHIBITION; GENE LOCATION; HOMOLOGOUS RECOMBINATION; HUMAN; HUMAN CELL; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN LOCALIZATION; PROTEIN TARGETING; TUMOR SUPPRESSOR GENE; TUMOR XENOGRAFT;

ANIMALS; BREAST NEOPLASMS; CELL NUCLEUS; CYTOPLASM; DNA BREAKS, DOUBLE-STRANDED; DNA REPAIR; ENZYME INHIBITORS; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; MCF-7 CELLS; MICE; POLY(ADP-RIBOSE) POLYMERASES; PROTEIN TRANSPORT; TRANSPLANTATION, HETEROLOGOUS; UBIQUITIN-PROTEIN LIGASES;

EID: 84868237277     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-12-0934     Document Type: Article

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