Loss-of-function mutations in MC4R are very rare in the Greek severely obese adult population

Obesity

Volumn 20, Issue 11, 2012, Pages 2278-2282

  Rouskas, Konstantinos ^a,b   Meyre, David ^b,c   Stutzmann, Fanny ^b   Paletas, Konstantinos ^d   Papazoglou, Dimitrios ^e   Vatin, Vincent ^b   Marchand, Marion ^b   Kouvatsi, Anastasia ^a   Froguel, Philippe ^b,f  

^a ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

^b INSTITUT PASTEUR DE LILLE   (France)

^c MCMASTER UNIVERSITY   (Canada)

^d ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

^e DEMOCRITUS UNIVERSITY OF THRACE   (Greece)

^f HAMMERSMITH HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

MELANOCORTIN 4 RECEPTOR;

AGED; ARTICLE; CASE CONTROL STUDY; CONTROLLED STUDY; DISEASE SEVERITY; DNA POLYMORPHISM; EMBRYO; FEMALE; GENE DELETION; GENETIC VARIABILITY; GREECE; HETEROZYGOTE; HUMAN; HUMAN CELL; IN VITRO STUDY; LEAN BODY WEIGHT; LOSS OF FUNCTION MUTATION; MAJOR CLINICAL STUDY; MALE; MC4R GENE; OBESITY; PEDIGREE; PENETRANCE; POPULATION GENETICS; PREVALENCE; PROTEIN FUNCTION;

AGED; BODY FAT DISTRIBUTION; CASE-CONTROL STUDIES; FEMALE; GREECE; HUMANS; MALE; MIDDLE AGED; MUTATION, MISSENSE; OBESITY, MORBID; PEDIGREE; PHENOTYPE; RECEPTOR, MELANOCORTIN, TYPE 4; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION;

EID: 84868193354     PISSN: 19307381     EISSN: 1930739X     Source Type: Journal    
DOI: 10.1038/oby.2012.77     Document Type: Article

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