-
1
-
-
0031781779
-
Meta-analysis of the association of the Trp64Arg polymorphism in the β3 adrenergic receptor with body mass index
-
Allison DB, Heo M, Faith MS, Pietrobelli A (1998) Meta-analysis of the association of the Trp64Arg polymorphism in the β3 adrenergic receptor with body mass index. Int J Obes Relat Metab Disord 22:559-566
-
(1998)
Int J Obes Relat Metab Disord
, vol.22
, pp. 559-566
-
-
Allison, D.B.1
Heo, M.2
Faith, M.S.3
Pietrobelli, A.4
-
2
-
-
0029839328
-
Morphine down-regulates melanocortin-4 receptor expression in brain regions that mediate opiate addiction
-
Alvaro JD, Tatro JB, Quillan JM, Fogliano M, Eisenhard M, Lerner MR, Nestler EJ, Duman RS (1996) Morphine down-regulates melanocortin-4 receptor expression in brain regions that mediate opiate addiction. Mol Pharmacol 50:583-591
-
(1996)
Mol Pharmacol
, vol.50
, pp. 583-591
-
-
Alvaro, J.D.1
Tatro, J.B.2
Quillan, J.M.3
Fogliano, M.4
Eisenhard, M.5
Lerner, M.R.6
Nestler, E.J.7
Duman, R.S.8
-
3
-
-
0030983833
-
Mutations of the human thyrotropin receptor gene causing thyroid hypoplasia and persistent congenital hypothyroidism
-
Biebermann H, Schoneberg T, Krude H, Schultz G, Gudermann T, Gruters A (1997) Mutations of the human thyrotropin receptor gene causing thyroid hypoplasia and persistent congenital hypothyroidism. J Clin Endocrinol Metab 82:3471-3480
-
(1997)
J Clin Endocrinol Metab
, vol.82
, pp. 3471-3480
-
-
Biebermann, H.1
Schoneberg, T.2
Krude, H.3
Schultz, G.4
Gudermann, T.5
Gruters, A.6
-
5
-
-
0037456733
-
Binge eating as a major phenotype of melanocortin 4 receptor gene mutations
-
Branson R, Potoczna N, Kral JG, Lentes KU, Hoehe MR, Horber FF (2003) Binge eating as a major phenotype of melanocortin 4 receptor gene mutations. N Engl J Med 348:1096-1103
-
(2003)
N Engl J Med
, vol.348
, pp. 1096-1103
-
-
Branson, R.1
Potoczna, N.2
Kral, J.G.3
Lentes, K.U.4
Hoehe, M.R.5
Horber, F.F.6
-
6
-
-
0003492892
-
-
International Agency for Research on Cancer Scientific Publications No. 32, International Agency for Research on Cancer Scientific Publications, Lyon
-
Breslow NE, Day NE (1980) Statistical methods in cancer research volume 1: the analysis of case-control studies. International Agency for Research on Cancer Scientific Publications No. 32, International Agency for Research on Cancer Scientific Publications, Lyon
-
(1980)
Statistical Methods in Cancer Research Volume 1: The Analysis of Case-control Studies
, vol.1
-
-
Breslow, N.E.1
Day, N.E.2
-
7
-
-
0034905674
-
Mutational analysis of melanocortin-4 receptor, agouti-related protein, and α-melanocyte-stimulating hormone genes in severely obese children
-
Dubern B, Clement K, Pelloux V, Froguel P, Girardet JP, Guy-Grand B, Tounian P (2001) Mutational analysis of melanocortin-4 receptor, agouti-related protein, and α-melanocyte-stimulating hormone genes in severely obese children. J Pediatr 139:204-209
-
(2001)
J Pediatr
, vol.139
, pp. 204-209
-
-
Dubern, B.1
Clement, K.2
Pelloux, V.3
Froguel, P.4
Girardet, J.P.5
Guy-Grand, B.6
Tounian, P.7
-
8
-
-
0035955871
-
Mouse melanocortin-4 receptor gene 5′-flanking region imparts cell specific expression in vitro
-
Dumont LM, Wu CS, Aschkenasi CJ, Elmquist JK, Lowell BB, Mountjoy KG (2001) Mouse melanocortin-4 receptor gene 5′-flanking region imparts cell specific expression in vitro. Mol Cell Endocrinol 184:173-185
-
(2001)
Mol Cell Endocrinol
, vol.184
, pp. 173-185
-
-
Dumont, L.M.1
Wu, C.S.2
Aschkenasi, C.J.3
Elmquist, J.K.4
Lowell, B.B.5
Mountjoy, K.G.6
-
9
-
-
0031955518
-
Base-calling of automated sequencer traces using Phred. I. Accuracy assessment
-
Ewing B, Hillier L, Wendl MC, Green P (1998) Base-calling of automated sequencer traces using Phred. I. Accuracy assessment. Genome Res 8:175-185
-
(1998)
Genome Res
, vol.8
, pp. 175-185
-
-
Ewing, B.1
Hillier, L.2
Wendl, M.C.3
Green, P.4
-
10
-
-
0037456768
-
Clinical spectrum of obesity and mutations in the melanocortin 4 receptor gene
-
Farooqi IS, Keogh JM, Yeo GS, Lank EJ, Cheetham T, O'Rahilly S (2003) Clinical spectrum of obesity and mutations in the melanocortin 4 receptor gene. N Engl J Med 348:1085-1095
-
(2003)
N Engl J Med
, vol.348
, pp. 1085-1095
-
-
Farooqi, I.S.1
Keogh, J.M.2
Yeo, G.S.3
Lank, E.J.4
Cheetham, T.5
O'Rahilly, S.6
-
11
-
-
0343953074
-
Dominant and recessive inheritance of morbid obesity associated with melanocortin 4 receptor deficiency
-
Farooqi IS, Yeo GS, Keogh JM, Aminian S, Jebb SA, Butler G, Cheetham T, O'Rahilly S (2000) Dominant and recessive inheritance of morbid obesity associated with melanocortin 4 receptor deficiency. J Clin Invest 106:271-279
-
(2000)
J Clin Invest
, vol.106
, pp. 271-279
-
-
Farooqi, I.S.1
Yeo, G.S.2
Keogh, J.M.3
Aminian, S.4
Jebb, S.A.5
Butler, G.6
Cheetham, T.7
O'Rahilly, S.8
-
12
-
-
0035663437
-
Farming, rural lifestyle and atopy in adults from southern Germany: Results from the MONICA/KORA study Augsburg
-
Filipiak B, Heinrich J, Schafer T, Ring J, Wichmann HE (2001) Farming, rural lifestyle and atopy in adults from southern Germany: results from the MONICA/KORA study Augsburg. Clin Exp Allergy 31:1829-1838
-
(2001)
Clin Exp Allergy
, vol.31
, pp. 1829-1838
-
-
Filipiak, B.1
Heinrich, J.2
Schafer, T.3
Ring, J.4
Wichmann, H.E.5
-
13
-
-
0031787748
-
Meta-analysis of the association of Trp64Arg polymorphism of β 3-adrenergic receptor gene with body mass index
-
Fujisawa T, Ikegami H, Kawaguchi Y, Ogihara T (1998) Meta-analysis of the association of Trp64Arg polymorphism of β 3-adrenergic receptor gene with body mass index. J Clin Endocrinol Metab 83:2441-2444
-
(1998)
J Clin Endocrinol Metab
, vol.83
, pp. 2441-2444
-
-
Fujisawa, T.1
Ikegami, H.2
Kawaguchi, Y.3
Ogihara, T.4
-
14
-
-
0030740803
-
Molecular screening of the human melanocortin-4 receptor gene: Identification of a missense variant showing no association with obesity, plasma glucose, or insulin
-
Gotoda T, Scott J, Aitman TJ (1997) Molecular screening of the human melanocortin-4 receptor gene: identification of a missense variant showing no association with obesity, plasma glucose, or insulin. Diabetologia 40:976-979
-
(1997)
Diabetologia
, vol.40
, pp. 976-979
-
-
Gotoda, T.1
Scott, J.2
Aitman, T.J.3
-
15
-
-
0033010326
-
Identification and functional analysis of novel human melanocortin-4 receptor variants
-
Gu W, Tu Z, Kleyn PW, Kissebah A, Duprat L, Lee J, Chin W, Maruti S, Deng N, Fisher SL, Franco LS, Burn P, Yagaloff KA, Nathan J, Heymsfield S, Albu J, Pi-Sunyer FX, Allison DB (1999) Identification and functional analysis of novel human melanocortin-4 receptor variants. Diabetes 48:635-639
-
(1999)
Diabetes
, vol.48
, pp. 635-639
-
-
Gu, W.1
Tu, Z.2
Kleyn, P.W.3
Kissebah, A.4
Duprat, L.5
Lee, J.6
Chin, W.7
Maruti, S.8
Deng, N.9
Fisher, S.L.10
Franco, L.S.11
Burn, P.12
Yagaloff, K.A.13
Nathan, J.14
Heymsfield, S.15
Albu, J.16
Pi-Sunyer, F.X.17
Allison, D.B.18
-
16
-
-
0034861789
-
Bovine melanocortin receptor 4: cDNA sequence, polymorphisms and mapping
-
Haegeman A, Coopman F, Jacobs K, Mattheeuws M, Van Zeveren A, Peelman L (2001) Bovine melanocortin receptor 4: cDNA sequence, polymorphisms and mapping. Anim Genet 32:189-192
-
(2001)
Anim Genet
, vol.32
, pp. 189-192
-
-
Haegeman, A.1
Coopman, F.2
Jacobs, K.3
Mattheeuws, M.4
Van Zeveren, A.5
Peelman, L.6
-
17
-
-
18344396039
-
A meta-analytic investigation of linkage and association of common leptin receptor (LEPR) polymorphisms with body mass index and waist circumference
-
Heo M, Leibel RL, Fontaine KR, Boyer BB, Chung WK, Koulu M, Karvonen MK, et al (2002) A meta-analytic investigation of linkage and association of common leptin receptor (LEPR) polymorphisms with body mass index and waist circumference. Int J Obes Relat Metab Disord 26:640-646
-
(2002)
Int J Obes Relat Metab Disord
, vol.26
, pp. 640-646
-
-
Heo, M.1
Leibel, R.L.2
Fontaine, K.R.3
Boyer, B.B.4
Chung, W.K.5
Koulu, M.6
Karvonen, M.K.7
-
18
-
-
0041708012
-
Binge eating as a phenotype of melanocortin 4 receptor gene mutations
-
Herpertz S, Siffert W, Hebebrand J (2003) Binge eating as a phenotype of melanocortin 4 receptor gene mutations. N Engl J Med 349:606-609
-
(2003)
N Engl J Med
, vol.349
, pp. 606-609
-
-
Herpertz, S.1
Siffert, W.2
Hebebrand, J.3
-
19
-
-
0141564582
-
Melanocortin-4 receptor gene: Case-control study and transmission disequilibrium test confirm that functionally relevant mutations are compatible with a major gene effect for extreme obesity
-
Hinney A, Hohmann S, Geller F, Vogel C, Hess C, Wermter AK, Brokamp B, Goldschmidt H, Siegfried W, Remschmidt H, Schafer H, Gudermann T, Hebebrand J (2003) Melanocortin-4 receptor gene: case-control study and transmission disequilibrium test confirm that functionally relevant mutations are compatible with a major gene effect for extreme obesity. J Clin Endocrinol Metab 88:4258-4267
-
(2003)
J Clin Endocrinol Metab
, vol.88
, pp. 4258-4267
-
-
Hinney, A.1
Hohmann, S.2
Geller, F.3
Vogel, C.4
Hess, C.5
Wermter, A.K.6
Brokamp, B.7
Goldschmidt, H.8
Siegfried, W.9
Remschmidt, H.10
Schafer, H.11
Gudermann, T.12
Hebebrand, J.13
-
20
-
-
18644363563
-
Melanocortin 4 receptor sequence variations are seldom a cause of human obesity: The Swedish obese subjects, the HERITAGE family study, and a Memphis cohort
-
Jacobson P, Ukkola O, Rankinen T, Snyder EE, Leon AS, Rao DC, Skinner JS, Wilmore JH, Lonn L, Cowan GS Jr, Sjostrom L, Bouchard C (2002) Melanocortin 4 receptor sequence variations are seldom a cause of human obesity: the Swedish obese subjects, the HERITAGE family study, and a Memphis cohort. J Clin Endocrinol Metab 87:4442-4446
-
(2002)
J Clin Endocrinol Metab
, vol.87
, pp. 4442-4446
-
-
Jacobson, P.1
Ukkola, O.2
Rankinen, T.3
Snyder, E.E.4
Leon, A.S.5
Rao, D.C.6
Skinner, J.S.7
Wilmore, J.H.8
Lonn, L.9
Cowan Jr., G.S.10
Sjostrom, L.11
Bouchard, C.12
-
21
-
-
0033958732
-
A missense variant of the porcine melanocortin-4 receptor (MC4R) gene is associated with fatness, growth, and feed intake traits
-
Kim KS, Larsen N, Short T, Plastow G, Rothschild MF (2000) A missense variant of the porcine melanocortin-4 receptor (MC4R) gene is associated with fatness, growth, and feed intake traits. Mamm Genome 11:131-135
-
(2000)
Mamm Genome
, vol.11
, pp. 131-135
-
-
Kim, K.S.1
Larsen, N.2
Short, T.3
Plastow, G.4
Rothschild, M.F.5
-
22
-
-
85030885445
-
Promoter analysis of the melanocortin receptor type-4
-
Paper presented, Sunriver, OR, August
-
Lamar CR, Kesterson RA (2002) Promoter analysis of the melanocortin receptor type-4. Paper presented at the Fifth International Melanocortin Meeting, Sunriver, OR, August 25-28
-
(2002)
Fifth International Melanocortin Meeting
, pp. 25-28
-
-
Lamar, C.R.1
Kesterson, R.A.2
-
23
-
-
0037312921
-
Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease
-
Lohmueller KE, Pearce CL, Pike M, Lander ES, Hirschhorn JN (2003) Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease. Nat Genet 33:177-182
-
(2003)
Nat Genet
, vol.33
, pp. 177-182
-
-
Lohmueller, K.E.1
Pearce, C.L.2
Pike, M.3
Lander, E.S.4
Hirschhorn, J.N.5
-
24
-
-
0037350649
-
A novel nonsense mutation in the melanocortin-4 receptor associated with obesity in a Spanish population
-
Marti A, Corbalan MS, Forga L, Martinez JA, Hinney A, Hebebrand J (2003) A novel nonsense mutation in the melanocortin-4 receptor associated with obesity in a Spanish population. Int J Obes Relat Metab Disord 27:385-388
-
(2003)
Int J Obes Relat Metab Disord
, vol.27
, pp. 385-388
-
-
Marti, A.1
Corbalan, M.S.2
Forga, L.3
Martinez, J.A.4
Hinney, A.5
Hebebrand, J.6
-
25
-
-
0037371453
-
Undetected genotyping errors cause apparent overtransmission of common alleles in the transmission/disequilibrium test
-
Mitchell AA, Cutler DJ, Chakravarti A (2003) Undetected genotyping errors cause apparent overtransmission of common alleles in the transmission/disequilibrium test. Am J Hum Genet 72:598-610
-
(2003)
Am J Hum Genet
, vol.72
, pp. 598-610
-
-
Mitchell, A.A.1
Cutler, D.J.2
Chakravarti, A.3
-
26
-
-
0032231941
-
PedCheck: A program for identification of genotype incompatibilities in linkage analysis
-
O'Connell JR, Weeks DE (1998) PedCheck: a program for identification of genotype incompatibilities in linkage analysis. Am J Hum Genet 63:259-266
-
(1998)
Am J Hum Genet
, vol.63
, pp. 259-266
-
-
O'Connell, J.R.1
Weeks, D.E.2
-
27
-
-
0033495921
-
Molecular scanning for mutations in the melanocortin-4 receptor gene in obese/diabetic Japanese
-
Ohshiro Y, Sanke T, Ueda K, Shimajiri Y, Nakagawa T, Tsunoda K, Nishi M, Sasaki H, Takasu N, Nanjo K (1999) Molecular scanning for mutations in the melanocortin-4 receptor gene in obese/diabetic Japanese. Ann Hum Genet 63:483-487
-
(1999)
Ann Hum Genet
, vol.63
, pp. 483-487
-
-
Ohshiro, Y.1
Sanke, T.2
Ueda, K.3
Shimajiri, Y.4
Nakagawa, T.5
Tsunoda, K.6
Nishi, M.7
Sasaki, H.8
Takasu, N.9
Nanjo, K.10
-
28
-
-
0034969437
-
Are rare variants responsible for susceptibility to complex diseases?
-
Pritchard JK (2001) Are rare variants responsible for susceptibility to complex diseases? Am J Hum Genet 69:124-137
-
(2001)
Am J Hum Genet
, vol.69
, pp. 124-137
-
-
Pritchard, J.K.1
-
29
-
-
0034771191
-
A missense mutation in the human melanocortin-4 receptor gene in relation to abdominal obesity and salivary cortisol
-
Rosmond R, Chagnon M, Bouchard C, Bjorntorp P (2001) A missense mutation in the human melanocortin-4 receptor gene in relation to abdominal obesity and salivary cortisol. Diabetologia 44:1335-1338
-
(2001)
Diabetologia
, vol.44
, pp. 1335-1338
-
-
Rosmond, R.1
Chagnon, M.2
Bouchard, C.3
Bjorntorp, P.4
-
30
-
-
0027992091
-
Comparison of statistics for candidate-gene association studies using cases and parents
-
Schaid DJ, Sommer SS (1994) Comparison of statistics for candidate-gene association studies using cases and parents. Am J Hum Genet 55:402-409
-
(1994)
Am J Hum Genet
, vol.55
, pp. 402-409
-
-
Schaid, D.J.1
Sommer, S.S.2
-
31
-
-
0032794634
-
Worldwide ethnic distribution of the G protein β3 subunit 825T allele and its association with obesity in Caucasian, Chinese, and black African individuals
-
Siffert W, Forster P, Jockel KH, Mvere DA, Brinkmann B, Naber C, Crookes R, Du PH, Epplen JT, Fridey J, Freedman BI, Muller N, Stolke D, Sharma AM, Al Moutaery K, Grosse-Wilde H, Buerbaum B, Ehrlich T, Ahmad HR, Horsthemke B, Du Toit ED, Tiilikainen A, Ge J, Wang Y, Rosskopf D (1999) Worldwide ethnic distribution of the G protein β3 subunit 825T allele and its association with obesity in Caucasian, Chinese, and black African individuals. J Am Soc Nephrol 10:1921-1930
-
(1999)
J Am Soc Nephrol
, vol.10
, pp. 1921-1930
-
-
Siffert, W.1
Forster, P.2
Jockel, K.H.3
Mvere, D.A.4
Brinkmann, B.5
Naber, C.6
Crookes, R.7
Du, P.H.8
Epplen, J.T.9
Fridey, J.10
Freedman, B.I.11
Muller, N.12
Stolke, D.13
Sharma, A.M.14
Al Moutaery, K.15
Grosse-Wilde, H.16
Buerbaum, B.17
Ehrlich, T.18
Ahmad, H.R.19
Horsthemke, B.20
Du Toit, E.D.21
Tiilikainen, A.22
Ge, J.23
Wang, Y.24
Rosskopf, D.25
more..
-
32
-
-
0027377799
-
Transmission test for linkage disequilibrium: The insulin gene region and insulin-dependent diabetes mellitus (IDDM)
-
Spielman RS, McGinnis RE, Ewens WJ (1993) Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM). Am J Hum Genet 52:506-516
-
(1993)
Am J Hum Genet
, vol.52
, pp. 506-516
-
-
Spielman, R.S.1
McGinnis, R.E.2
Ewens, W.J.3
-
33
-
-
0033927916
-
Melanocortin-4 receptor mutations are a frequent and heterogeneous cause of morbid obesity
-
Vaisse C, Clement K, Durand E, Hercberg S, Guy-Grand B, Froguel P (2000) Melanocortin-4 receptor mutations are a frequent and heterogeneous cause of morbid obesity. J Clin Invest 106:253-262
-
(2000)
J Clin Invest
, vol.106
, pp. 253-262
-
-
Vaisse, C.1
Clement, K.2
Durand, E.3
Hercberg, S.4
Guy-Grand, B.5
Froguel, P.6
-
34
-
-
0037370188
-
Improving the prediction of complex diseases by testing for multiple disease-susceptibility genes
-
Yang Q, Khoury MJ, Botto L, Friedman JM, Flanders WD (2003) Improving the prediction of complex diseases by testing for multiple disease-susceptibility genes. Am J Hum Genet 72:636-649
-
(2003)
Am J Hum Genet
, vol.72
, pp. 636-649
-
-
Yang, Q.1
Khoury, M.J.2
Botto, L.3
Friedman, J.M.4
Flanders, W.D.5
-
35
-
-
0037976417
-
An efficient procedure for genotyping single nucleotide polymorphisms
-
Ye S, Dhillon S, Ke X, Collins AR, Day IN (2001) An efficient procedure for genotyping single nucleotide polymorphisms. Nucleic Acids Res 29:E88
-
(2001)
Nucleic Acids Res
, vol.29
-
-
Ye, S.1
Dhillon, S.2
Ke, X.3
Collins, A.R.4
Day, I.N.5
-
36
-
-
0037341511
-
Mutations in the human melanocortin-4 receptor gene associated with severe familial obesity disrupts receptor function through multiple molecular mechanisms
-
Yeo GS, Lank EJ, Farooqi IS, Keogh J, Challis BG, O'Rahilly S (2003) Mutations in the human melanocortin-4 receptor gene associated with severe familial obesity disrupts receptor function through multiple molecular mechanisms. Hum Mol Genet 12:561-574
-
(2003)
Hum Mol Genet
, vol.12
, pp. 561-574
-
-
Yeo, G.S.1
Lank, E.J.2
Farooqi, I.S.3
Keogh, J.4
Challis, B.G.5
O'Rahilly, S.6
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