TNF-dependent signaling pathways in liver cancer: Promising targets for therapeutic strategies?

Digestive Diseases

Volumn 30, Issue 5, 2012, Pages 500-507

  Roderburg, Christoph ^a   Gautheron, Jeremie ^a   Luedde, Tom ^a  

^a UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

Author keywords

Hepatocellular carcinoma; Inflammation; JNK; Mouse models; NF B; p38 ; Tumor necrosis factor

Indexed keywords

CRE RECOMBINASE; DIETHYLNITROSAMINE; I KAPPA B; I KAPPA B KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN INHIBITOR; RECOMBINANT TUMOR NECROSIS FACTOR; STAT3 INHIBITOR; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR RECEPTOR; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CELL TYPE; CYTOKINE PRODUCTION; DRUG EFFICACY; DRUG INHIBITION; DRUG MECHANISM; DRUG SAFETY; GENE EXPRESSION; GENE TARGETING; HISTOPATHOLOGY; HUMAN; LIVER; LIVER CANCER; LIVER CARCINOGENESIS; LIVER CELL; LIVER CELL CARCINOMA; LOXP SITE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TUMOR CELL; TUMOR VOLUME; TUMOR XENOGRAFT;

ANIMALS; ANTINEOPLASTIC AGENTS; CARCINOMA, HEPATOCELLULAR; CELL TRANSFORMATION, NEOPLASTIC; FEMALE; HUMANS; LIVER NEOPLASMS; MALE; MICE; MICE, KNOCKOUT; SIGNAL TRANSDUCTION; TRANSLATIONAL MEDICAL RESEARCH; TUMOR NECROSIS FACTORS;

EID: 84868116084     PISSN: 02572753     EISSN: 14219875     Source Type: Journal    
DOI: 10.1159/000341700     Document Type: Article

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