Dynamics of bleomycin interaction with a strongly bound hairpin DNA substrate, and implications for cleavage of the bound DNA

Journal of the American Chemical Society

Volumn 134, Issue 43, 2012, Pages 17842-17845

  Bozeman, Trevor C ^a   Nanjunda, Rupesh ^b   Tang, Chenhong ^a   Liu, Yang ^b   Segerman, Zachary J ^a   Zaleski, Paul A ^a   Wilson, W David ^b   Hecht, Sidney M ^a  

^a ARIZONA STATE UNIVERSITY   (United States)

^b GEORGIA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTITUMOR ANTIBIOTICS; BLEOMYCINS; CLEAVAGE SITES; DNA BINDING SITE; DNA CLEAVAGE; DNA DEGRADATION; DNA SUBSTRATES; H-ATOM ABSTRACTION; INTRINSIC RATES;

BINDING SITES; DYNAMICS;

DNA;

BLEOMYCIN; DNA; SODIUM CHLORIDE;

ARTICLE; BINDING SITE; DNA CLEAVAGE; DNA DEGRADATION; DNA HAIRPIN; DRUG DNA BINDING; SURFACE PLASMON RESONANCE; TEMPERATURE;

ANTIBIOTICS, ANTINEOPLASTIC; BLEOMYCIN; DNA; DNA CLEAVAGE; MOLECULAR STRUCTURE; SURFACE PLASMON RESONANCE; THERMODYNAMICS;

EID: 84868092698     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja306233e     Document Type: Article

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