Inhibition of long-chain Acyl coenzyme a synthetases during fatty acid loading induces lipotoxicity in macrophages

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 29, Issue 11, 2009, Pages 1937-1943

  Saraswathi, Viswanathan ^a   Hasty, Alyssa H ^a  

^a VANDERBILT UNIVERSITY   (United States)

Author keywords

Foam cells; Free fatty acids; Long chain acyl CoA synthetases; Stearic acid; Triacsin C; VLDL

Indexed keywords

FATTY ACID; LONG CHAIN FATTY ACID COENZYME A LIGASE; MESSENGER RNA; STEARIC ACID; TRIACYLGLYCEROL; VERY LOW DENSITY LIPOPROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ATHEROSCLEROSIS; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DYSLIPIDEMIA; ENZYME INHIBITION; FATTY ACID METABOLISM; FEMALE; FOAM CELL; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; LIPOTOXICITY; MALE; MOUSE; NONHUMAN; OBESITY; PERITONEUM MACROPHAGE; PRIORITY JOURNAL;

ANIMALS; APOPTOSIS; CELL SURVIVAL; CELLS, CULTURED; CHOLESTEROL, VLDL; COENZYME A LIGASES; FATTY ACIDS, NONESTERIFIED; LIPID METABOLISM; MACROPHAGES, PERITONEAL; MICE; SENSITIVITY AND SPECIFICITY; TRIAZENES;

EID: 73949094213     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/ATVBAHA.109.195362     Document Type: Article

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