Molecular mimicry may contribute to pathogenesis of ulcerative colitis

FEBS Letters

Volumn 579, Issue 11, 2005, Pages 2261-2266

  Kovvali, Gopala ^a   Das, Kiron M ^a  

^a ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

Author keywords

Autoimmunity; Chaperone; Epitope; Heat shock protein; Major histocompatibility complex; Molecular mimicry; Tropomyosin; Ulcerative colitis

Indexed keywords

BACTERIAL PROTEIN; NEUTROPHIL CYTOPLASMIC ANTIBODY; TROPOMYOSIN;

AMINO ACID SEQUENCE; ARTICLE; AUTOIMMUNE DISEASE; AUTOIMMUNITY; BACTERIAL GENOME; COLON MUCOSA; CROHN DISEASE; DATA BASE; HUMAN; IMMUNE RESPONSE; IMMUNOREACTIVITY; INFECTION; MOLECULAR MIMICRY; NONHUMAN; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PRIORITY JOURNAL; SEQUENCE HOMOLOGY; STATISTICAL SIGNIFICANCE; T LYMPHOCYTE; ULCERATIVE COLITIS;

EID: 17644385528     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2005.02.073     Document Type: Article

References (78)

1. N.R. Rose Infection, mimics, and autoimmune disease J. Clin. Invest. 107 2001 943 944
2. M. Kotb Infection and autoimmunity: a story of the host, the pathogen, and the copathogen Clin. Immunol. Immunopathol. 74 1995 10 22
3. R.S. Fujinami, M.B. Oldstone, Z. Wroblewska, M.E. Frankel, and H. Koprowski Molecular mimicry in virus infection: crossreaction of measles virus phosphoprotein or of Herpes simplex virus protein with human intermediate filaments Proc. Natl. Acad. Sci. USA 80 1983 2346 2350
4. I.R. Cohen The cognitive paradigm and the immunological homunculus Immunol. Today 13 1992 490 494
5. I.R. Cohen The cognitive principle challenges clonal selection Immunol. Today 13 1992 441 444
6. H. Tiwana, C. Wilson, A. Alvarez, R. Abuknesha, S. Bansal, and A. Ebringer Cross-reactivity between the rheumatoid arthritis-associated motif EQKRAA and structurally related sequences found in Proteus mirabilis Infect. Immun. 67 1999 2769 2775
7. S.L. Bridges Update on autoantibodies in rheumatoid arthritis Curr. Rheumatol. Rep. 6 2004 343 350
8. N. Balandraud, J. Roudier, and C. Roudier Epstein-Barr virus and rheumatoid arthritis Autoimmun. Rev. 3 2004 362 367
9. C.R. Chen, K. Tanaka, G.D. Chazenbalk, S.M. McLachlan, and B. Rapoport A full biological response to autoantibodies in Graves' disease requires a disulfide-bonded loop in the thyrotropin receptor N terminus homologous to a laminin epidermal growth factor-like domain J. Biol. Chem. 276 2001 14767 14772
10. L.D. Kohn, G. Napolitano, D.S. Singer, M. Molteni, R. Scorza, N. Shimojo, Y. Kohno, E. Mozes, M. Nakazato, L. Ulianich, H.K. Chung, H. Matoba, B. Saunier, K. Suzuki, F. Schuppert, and M. Saji Graves' disease: a host defense mechanism gone awry Int. Rev. Immunol. 19 2000 633 664
11. M. Fielder, S.J. Pirt, I. Tarpey, C. Wilson, P. Cunningham, C. Ettelaie, A. Binder, S. Bansal, and A. Ebringer Molecular mimicry and ankylosing spondylitis: possible role of a novel sequence in pullulanase of Klebsiella pneumoniae FEBS Lett. 369 1995 243 248
12. A. Ebringer Ankylosing spondylitis is caused by Klebsiella. Evidence from immunogenetic, microbiologic, and serologic studies Rheum. Dis. Clin. North Am. 18 1992 105 121
13. L. Ronnblom, and G.V. Alm An etiopathogenic role for the type I IFN system in SLE Trends Immunol. 22 2001 427 431
14. M.T. McClain, L.D. Heinlen, G.J. Dennis, J. Roebuck, J.B. Harley, and J.A. James Early events in lupus humoral autoimmunity suggest initiation through molecular mimicry Nat. Med. 11 2005 85 89
15. K.M. Kaufman, M.Y. Kirby, J.B. Harley, and J.A. James Peptide mimics of a major lupus epitope of SmB/B' Ann. N. Y. Acad. Sci. 987 2003 215 229
16. N.R. Rose, and I.R. Mackay Molecular mimicry: a critical look at exemplary instances in human diseases Cell Mol. Life Sci. 57 2000 542 551
17. H.S. Hiemstra, N.C. Schloot, P.A. van Veelen, S.J. Willemen, K.L. Franken, J.J. van Rood, R.R. de Vries, A. Chaudhuri, P.O. Behan, J.W. Drijfhout, and B.O. Roep Cytomegalovirus in autoimmunity: T cell crossreactivity to viral antigen and autoantigen glutamic acid decarboxylase Proc. Natl. Acad. Sci. USA 98 2001 3988 3991
18. I. Ferrari, M.J. Levin, G. Wallukat, R. Elies, D. Lebesgue, P. Chiale, M. Elizari, M. Rosenbaum, and J. Hoebeke Molecular mimicry between the immunodominant ribosomal protein P0 of Trypanosoma cruzi and a functional epitope on the human beta 1-adrenergic receptor J. Exp. Med. 182 1995 59 65
19. C.A. Bona Molecular mimicry of self-antigens Immunol. Ser. 55 1991 239 246
20. E.E. Sercarz, P.V. Lehmann, A. Ametani, G. Benichou, A. Miller, and K. Moudgil Dominance and crypticity of T cell antigenic determinants Annu. Rev. Immunol. 11 1993 729 766
21. K. Krisher, and M.W. Cunningham Myosin: a link between streptococci and heart Science 227 1985 413 415
22. J.B. Dale, and E.H. Beachey Epitopes of streptococcal M proteins shared with cardiac myosin J. Exp. Med. 162 1985 583 591
23. J.B. Zabriskie Rheumatic fever: a model for the pathological consequences of microbial-host mimicry Clin. Exp. Rheumatol. 4 1986 65 73
24. E.H. Beachey, M. Bronze, J.B. Dale, W. Kraus, T. Poirier, and S. Sargent Protective and autoimmune epitopes of streptococcal M proteins Vaccine 6 1988 192 196
25. C.R. Parish, and E.R. O'Neill Dependence of the adaptive immune response on innate immunity: some questions answered but new paradoxes emerge Immunol. Cell Biol. 75 1997 523 527
26. M.B. Oldstone Molecular mimicry and autoimmune disease Cell 50 1987 819 820
27. I.R. Cohen Antigenic mimicry, clonal selection and autoimmunity Journal of Autoimmunity 16 2001 337 340
28. C.B. Anfinsen The formation and stabilization of protein structure Biochem. J. 128 1972 737 749
29. D.B. Jones, A.F. Coulson, and G.W. Duff Sequence homologies between hsp60 and autoantigens Immunol. Today 14 1993 115 118
30. P. Brandtzaeg Autoimmunity and ulcerative colitis: can two enigmas make sense together? Gastroenterology 109 1995 307 312
31. B.A. Hendrickson, R. Gokhale, and J.H. Cho Clinical aspects and pathophysiology of inflammatory bowel disease Clin. Microbiol. Rev. 15 2002 79 94
32. T.T. MacDonald, G. Monteleone, and S.L. Pender Recent developments in the immunology of inflammatory bowel disease Scand. J. Immunol. 51 2000 2 9
33. J.P. Olives, A. Breton, J.P. Hugot, F. Oksman, C. Johannet, J. Ghisolfi, J. Navarro, and J.P. Cezard Antineutrophil cytoplasmic antibodies in children with inflammatory bowel disease: prevalence and diagnostic value J. Pediatr. Gastroenterol. Nutr. 25 1997 142 148
34. S.R. Targan, C.J. Landers, L. Cobb, R.P. MacDermott, and A. Vidrich Perinuclear anti-neutrophil cytoplasmic antibodies are spontaneously produced by mucosal B cells of ulcerative colitis patients J. Immunol. 155 1995 3262 3267
35. O. Cohavy, D. Bruckner, L.K. Gordon, R. Misra, B. Wei, M.E. Eggena, S.R. Targan, and J. Braun Colonic bacteria express an ulcerative colitis pANCA-related protein epitope Infect. Immun. 68 2000 1542 1548
36. C. Folwaczny, N. Noehl, K. Tschop, S.P. Endres, W. Heldwein, K. Loeschke, and H. Fricke Goblet cell autoantibodies in patients with inflammatory bowel disease and their first-degree relatives Gastroenterology 113 1997 101 106
37. B. Sadlack, H. Merz, H. Schorle, A. Schimpl, A.C. Feller, and I. Horak Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene Cell 75 1993 253 261
38. R. Kuhn, J. Lohler, D. Rennick, K. Rajewsky, and W. Muller Interleukin-10-deficient mice develop chronic enterocolitis Cell 75 1993 263 274
39. P. Mombaerts, E. Mizoguchi, M.J. Grusby, L.H. Glimcher, A.K. Bhan, and S. Tonegawa Spontaneous development of inflammatory bowel disease in T cell receptor mutant mice Cell 75 1993 274 282
40. R.E. Hammer, S.D. Maika, J.A. Richardson, J.P. Tang, and J.D. Taurog Spontaneous inflammatory disease in transgenic rats expressing HLA-B27 and human beta 2m: an animal model of HLA-B27-associated human disorders Cell 63 1990 1099 1112
41. R.B. Sartor Cytokines in intestinal inflammation: pathophysiological and clinical considerations Gastroenterology 106 1994 533 539
42. W. Strober, I.J. Fuss, and R.S. Blumberg The immunology of mucosal models of inflammation Annu. Rev. Immunol. 20 2002 495 549
43. L.J. Albert, and R.D. Inman Molecular mimicry and autoimmunity N. Engl. J. Med. 341 1999 2068 2074
44. A. Saxon, F. Shanahan, C. Landers, T. Ganz, and S. Targan A distinct subset of antineutrophil cytoplasmic antibodies is associated with inflammatory bowel disease J. Allergy Clin. Immunol. 86 1990 202 210
45. R.H. Duerr, S.R. Targan, C.J. Landers, N.F. LaRusso, K.L. Lindsay, R.H. Wiesner, and F. Shanahan Neutrophil cytoplasmic antibodies: a link between primary sclerosing cholangitis and ulcerative colitis Gastroenterology 100 1991 1385 1391
46. K.M. Das, A. Dasgupa, A. Mandel, and X. Gen Autoimmunity to cytoskeletal protein tropomyosin. A clue to the pathogenetic mechanism for ulcerative colitis J. Immunol. 150 1993 2487 2493
47. L. Biancone, A. Mandal, H. Yang, A. Dasgupta, A.O. Paoluzi, A. Marcheggiano, F. Paoluzi, and K.M. Das Production of immunoglobulin G and G1 antibodies to cytoskeletal protein by lamina propria cells in ulcerative colitis. Production of immunoglobulin G and G1 antibodies to cytoskeletal protein by lamina propria cells in ulcerative colitis Gasteroenterology 109 1995 3 12
48. X. Geng, L. Biancone, H.H. Dai, J.J. Lin, N. Yoshizaki, A. Dasgupta, F. Pallone, and K.M. Das Tropomyosin isoforms in intestinal mucosa: production of autoantibodies to tropomyosin isoforms in ulcerative colitis Gastroenterology 114 1998 912 922
49. L. Biancone, I. Monteleone, G. Blanco, P. Vavassori, and F. Pallone Del Vecchio resident bacterial flora and immune system Dig. Liver Dis. 34 Suppl. 2 2002 S37 S43
50. L. Biancone, G. Monteleone, R. Marasco, and F. Pallione Autoimmunity to tropomyosin isoforms in ulcerative colitis (UC) patients and unaffected relatives Clin. Exp. Immunol. 113 1998 198 205
51. E.K. Onuma, P.S. Amenta, K. Ramaswamy, J.J. Lin, and K.M. Das Autoimmunity in ulcerative colitis (UC): a predominant colonic mucosal B cell response against human tropomyosin isoform 5 Clin. Exp. Immunol 121 2000 466 471
52. K.M. Das Relationship of extraintestinal involvements in inflammatory bowel disease: new insights into autoimmune pathogenesis Dig. Dis. Sci. 44 1999 1 13
53. N. Ivanova, A. Sorokin, I. Anderson, N. Galleron, B. Candelon, V. Kapatral, A. Bhattacharyya, G. Reznik, N. Mikhailova, A. Lapidus, L. Chu, M. Mazur, E. Goltsman, N. Larsen, M. D'Souza, T. Walunas, Y. Grechkin, G. Pusch, R. Haselkorn, M. Fonstein, D.S.D. Ehrlich, R. Overbeek, and N. Kyrpides Genome sequence of Bacillus cereus and comparative analysis with Bacillus anthracis Nature 423 2003 87 91
54. F. Mor, A. Weinberger, and I.R. Cohen Identification of alpha-tropomyosin as a target self-antigen in Behcet's syndrome Eur. J. Immunol. 32 2002 356 365
55. J.G. Dohlman, A. Lupas, and M. Carson Long charge-rich α-helices in systemic autoantigens Biochem. Biophys. Res. Commun. 195 1993 686 696
56. C. Benoist, and D. Mathis Autoimmunity provoked by infection:how good is the case for T cell epitope mimicry? Nat. Immunol. 2 2001 797 801
57. M.W. Cunningham Pathogenesis of group A streptococcal infections Clin. Microbiol. Rev. 13 2000 470 511
58. R.L. Tarleton, and L. Zhang Chagas disease etiology: autoimmunity or parasite persistence? Parasitol. Today 15 1999 94 99
59. P.J. Talbot, J.S. Paquette, C. Ciurli, J.P. Antel, and F. Ouellet Myelin basic protein and human coronavirus 229E cross-reactive T cells in multiple sclerosis Ann. Neurol. 39 1996 233 240
60. K. Banki, E. Colombo, F. Sia, D. Halladay, D.H. Mattson, A.H. Tatum, P.T. Massa, P.E. Phillips, and A. Perl Oligodendrocyte-specific expression and autoantigenicity of transaldolase in multiple sclerosis J. Exp. Med. 180 1994 1649 1663
61. K.W. Wucherpfennig, and J.L. Strominger Molecular mimicry in T-cell mediated autoimmunity: viral peptides activate human T-cell clones specific for myelin basic protein Cell 80 1995 695 705
62. N. Neu, N.R. Rose, K.W. Beisel, A. Herskowitz, G. Gurri-Glass, and S. Craig Cardiac myosin induces myocarditis in genetically predisposed mice J. Immunol. 139 1987 3630 3636
63. C.J. Gauntt, S.M. Tracy, N. Chapman, H.J. Wood, P.C. Kolbeck, A.G. Karaganis, C.L. Winfrey, and M.W. Cunningham Coxsackievirus-induced chronic myocarditis in murine models Eur. Heart J. 16 1995 56 58
64. K. Schulze, and H.P. Schultheiss The role of the ADP/ATP carrier in the pathogenesis of viral heart disease Eur. Heart J. 16 1995 64 67
65. C.W. Ang, B.C. Jacobs, and J.D. Laman The Guillain-Barr A syndrome: a true case of molecular mimicry Trends Immunol. 25 2004 61 66
66. S.A. Huber, A. Moraska, and M. Cunningham Alterations in major histocompatibility complex association of myocarditis induced by coxsackievirus B3 mutants selected with monoclonal antibodies to group A streptococci Proc. Natl. Acad. Sci. USA 91 1994 5543 5547
67. K. Krisher, and M.W. Cunningham Myosin: a link between streptococci and heart Science 227 1985 413
68. P.L. Schwimmbeck, T. Dyrberg, D.B. Drachman, and M.B.A. Oldstone Molecular mimicry and myasthenia gravis J. Clin. Invest. 84 1989 1174 1180
69. C. Hafer-Macko, S.T. Hsieh, C.Y. Li, T.W. Ho, K. Sheikh, D.R. Cornblath, G.M. McKhann, A.K. Asbury, and J.W. Griffin Acute motor axonal neuropathy: an antibody-mediated attack on axolemma Ann. Neurol. 40 1996 635 644
70. N. Yuki, Y. Tagawa, and S. Handa Autoantibodies to peripheral nerve glycosphingolipids SPG, SLPG, and SGPG in Guillain-Barre' syndrome and chronic inflammatory demyelinating polyneuropathy J. Neuroimmunol. 70 1996 1 6
71. A. Marx, A. Wilisch, A. Schultz, S. Gattenlohner, R. Nenninger, and H.K. Muller-Hermelink Pathogenesis of myasthenia gravis Virchows Arch. 430 1997 355 364
72. D.P. Richman, and M.A. Agius Acquired myasthenia gravis Neurol. Clin. 12 1994 273 284
73. M.F. Kagnoff Celiac disease: adenovirus and alpha gliadin Curr. Top. Microbiol. Immunol. 145 1989 67 78
74. L. Tuckova, H. Tlaskalova-Hogenova, M.A. Farre, K. Karska, P. Rossmann, J. Kolinska, and P. Kocna Molecular mimicry as a possible cause of autoimmune reactions in celiac disease? Antibodies to gliadin cross-react with epitopes on enterocytes Clin. Immunol. Immunopathol. 74 1995 170 176
75. S.R. Thurau, M. Diedrichs-Mohring, H. Fricke, S. Arbogast, and G. Wildner Molecular mimicry as a therapeutic approach for an autoimmune disease: oral treatment of uveitis patients with an MHC-peptide crossreactive with autoantigen first results Immunol. Lett. 57 1997 193 201
76. B.J. Appelmelk, I. Simoons-Smit, R. Negrini, A.P. Moran, G.O. Aspinall, J.G. Forte, T. De Vries, H. Quan, T. Verboom, J.J. Maaskant, P. Ghiara, E.J. Kuipers, E. Bloemena, T.M. Tadema, R.R. Townsend, K. Tyagarajan, J.M. Crothers Jr., M.A. Monteiro, A. Savio, and F.J. De Graaf Potential role of molecular mimicry between Helicobacter pylori lipopolysaccharide and host Lewis blood group antigens in autoimmunity Infect. Immun. 64 1996 2031 2040
77. S. Shimoda, M. Nakamura, H. Ishibashi, A. Kawano, T. Kamihira, N. Sakamoto, S. Matsushita, A. Tanaka, H.J. Worman, M.E. Gershwin, and M. Harada Molecular mimicry of mitochondrial and nuclear autoantigens in primary biliary cirrhosis Gastroenterology 124 2003 1915 1925
78. S.W. Rogers, P.I. Andrews, L.C. Gahring, T. Whisenand, K. Cauley, B. Crain, T.E. Hughes, S.F. Heinemann, and J.O. McNamara Autoantibodies to glutamate receptor GluR3 in Rasmussen's encephalitis Science 265 1994 648 651