메뉴 건너뛰기




Volumn 1484, Issue , 2012, Pages 29-38

Effects of resveratrol on blood homocysteine level, on homocysteine induced oxidative stress, apoptosis and cognitive dysfunctions in rats

Author keywords

Apoptosis; Cognitive function; Homocysteine; Oxidative stress; Resveratrol; TUNEL

Indexed keywords

HOMOCYSTEINE; MESSENGER RNA; METHIONINE; RESVERATROL;

EID: 84867893982     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2012.09.026     Document Type: Article
Times cited : (29)

References (76)
  • 1
    • 79958243683 scopus 로고    scopus 로고
    • Resveratrol shows vasoprotective effect reducing oxidative stress without affecting metabolic disturbances in insulin-dependent diabetes of rabbits
    • F. Akar, M.B. Pektas, C. Tufan, S. Soylemez, A. Sepici, A.T. Ulus, B. Gokalp, K. Ozturk, and H.S. Surucu Resveratrol shows vasoprotective effect reducing oxidative stress without affecting metabolic disturbances in insulin-dependent diabetes of rabbits Cardiovasc. Drugs. Ther. 25 2011 119 131
    • (2011) Cardiovasc. Drugs. Ther. , vol.25 , pp. 119-131
    • Akar, F.1    Pektas, M.B.2    Tufan, C.3    Soylemez, S.4    Sepici, A.5    Ulus, A.T.6    Gokalp, B.7    Ozturk, K.8    Surucu, H.S.9
  • 2
    • 0034141698 scopus 로고    scopus 로고
    • Relationships between homocysteine, factor VIIa, and thrombin generation in acute coronary syndromes
    • M.K. Al-Obaidi, H. Philippou, P.J. Stubbs, A. Adami, R. Amersey, M.M. Noble, and D.A. Lane Relationships between homocysteine, factor VIIa, and thrombin generation in acute coronary syndromes Circulation 101 2000 372 377
    • (2000) Circulation , vol.101 , pp. 372-377
    • Al-Obaidi, M.K.1    Philippou, H.2    Stubbs, P.J.3    Adami, A.4    Amersey, R.5    Noble, M.M.6    Lane, D.A.7
  • 3
    • 77951553013 scopus 로고    scopus 로고
    • Upregulation of proteinase-activated receptor-2 and increased response to trypsin in endothelial cells after exposure to oxidative stress in rat aortas
    • M. Aman, M. Hirano, H. Kanaide, and K. Hirano Upregulation of proteinase-activated receptor-2 and increased response to trypsin in endothelial cells after exposure to oxidative stress in rat aortas J. Vasc. Res. 47 2010 494 506
    • (2010) J. Vasc. Res. , vol.47 , pp. 494-506
    • Aman, M.1    Hirano, M.2    Kanaide, H.3    Hirano, K.4
  • 5
    • 0345047707 scopus 로고    scopus 로고
    • Oxidative stress-induced dysregulation of arteriolar wall shear stress and blood pressure in hyperhomocysteinemia is prevented by chronic vitamin C treatment
    • Z. Bagi, C. Cseko, E. Toth, and A. Koller Oxidative stress-induced dysregulation of arteriolar wall shear stress and blood pressure in hyperhomocysteinemia is prevented by chronic vitamin C treatment Am. J. Physiol. Heart Circ. Physiol. 285 2003 2277 2283
    • (2003) Am. J. Physiol. Heart Circ. Physiol. , vol.285 , pp. 2277-2283
    • Bagi, Z.1    Cseko, C.2    Toth, E.3    Koller, A.4
  • 6
    • 20144372783 scopus 로고    scopus 로고
    • Melatonin improves learning and memory performances impaired by hyperhomocysteinemia in rats
    • G. Baydas, M. Ozer, A. Yasar, M. Tuzcu, and S.T. Koz Melatonin improves learning and memory performances impaired by hyperhomocysteinemia in rats Brain Res. 1046 2005 187 194
    • (2005) Brain Res. , vol.1046 , pp. 187-194
    • Baydas, G.1    Ozer, M.2    Yasar, A.3    Tuzcu, M.4    Koz, S.T.5
  • 7
    • 26044482418 scopus 로고    scopus 로고
    • Melatonin inhibits neural apoptosis induced by homocysteine in hippocampus of rats via inhibition of cytochrome c translocation and caspase-3 activation and by regulating pro- and anti-apoptotic protein levels
    • G. Baydas, R.J. Reiter, M. Akbulut, M. Tuzcu, and S. Tamer Melatonin inhibits neural apoptosis induced by homocysteine in hippocampus of rats via inhibition of cytochrome c translocation and caspase-3 activation and by regulating pro- and anti-apoptotic protein levels Neuroscience 135 2005 879 886
    • (2005) Neuroscience , vol.135 , pp. 879-886
    • Baydas, G.1    Reiter, R.J.2    Akbulut, M.3    Tuzcu, M.4    Tamer, S.5
  • 8
    • 34247337709 scopus 로고    scopus 로고
    • Effects of maternal hyperhomocysteinemia induced by high methionine diet on the learning and memory performance in offspring
    • G. Baydas, S.T. Koz, M. Tuzcu, V.S. Nedzvetsky, and E. Etem Effects of maternal hyperhomocysteinemia induced by high methionine diet on the learning and memory performance in offspring Int. J. Dev. Neurosci. 25 2007 133 139
    • (2007) Int. J. Dev. Neurosci. , vol.25 , pp. 133-139
    • Baydas, G.1    Koz, S.T.2    Tuzcu, M.3    Nedzvetsky, V.S.4    Etem, E.5
  • 9
    • 70450242876 scopus 로고    scopus 로고
    • A new insight into resveratrol as an atheroprotective compound: Inhibition of lipid peroxidation and enhancement of cholesterol efflux
    • H. Berrougui, G. Grenier, S. Loued, G. Drouin, and A. Khalil A new insight into resveratrol as an atheroprotective compound: inhibition of lipid peroxidation and enhancement of cholesterol efflux Atherosclerosis 207 2009 420 427
    • (2009) Atherosclerosis , vol.207 , pp. 420-427
    • Berrougui, H.1    Grenier, G.2    Loued, S.3    Drouin, G.4    Khalil, A.5
  • 10
    • 77954537252 scopus 로고    scopus 로고
    • Assessment of 3-nitropropionic acid-evoked peripheral neuropathy in rats: Neuroprotective effects of acetyl-l-carnitine and resveratrol
    • Z.K. Binienda, M.A. Beaudoin, B. Gough, S.F. Ali, and A. Virmani Assessment of 3-nitropropionic acid-evoked peripheral neuropathy in rats: neuroprotective effects of acetyl-l-carnitine and resveratrol Neurosci. Lett. 480 2010 117 121
    • (2010) Neurosci. Lett. , vol.480 , pp. 117-121
    • Binienda, Z.K.1    Beaudoin, M.A.2    Gough, B.3    Ali, S.F.4    Virmani, A.5
  • 11
    • 34249846128 scopus 로고    scopus 로고
    • Resveratrol stimulates AMP kinase activity in neurons
    • B. Dasgupta, and J. Milbrandt Resveratrol stimulates AMP kinase activity in neurons Proc. Nat. Acad. Sci. U.S.A. 104 2007 7217 7222
    • (2007) Proc. Nat. Acad. Sci. U.S.A. , vol.104 , pp. 7217-7222
    • Dasgupta, B.1    Milbrandt, J.2
  • 12
    • 51649112963 scopus 로고    scopus 로고
    • Murine models of hyperhomocysteinemia and their vascular phenotypes
    • S. Dayal, and S.R. Lentz Murine models of hyperhomocysteinemia and their vascular phenotypes Arterioscler Thromb. Vasc. Biol. 28 2008 1596 1605
    • (2008) Arterioscler Thromb. Vasc. Biol. , vol.28 , pp. 1596-1605
    • Dayal, S.1    Lentz, S.R.2
  • 13
    • 0347316389 scopus 로고    scopus 로고
    • Potential role of p53 mutation in chemical hepatocarcinogenesis of rats
    • W.G. Deng, Y. Fu, Y.L. Li, and T. Sugiyama Potential role of p53 mutation in chemical hepatocarcinogenesis of rats World J. Gastroenterol. 10 2004 46 52
    • (2004) World J. Gastroenterol. , vol.10 , pp. 46-52
    • Deng, W.G.1    Fu, Y.2    Li, Y.L.3    Sugiyama, T.4
  • 14
    • 0037295102 scopus 로고    scopus 로고
    • Molecular mechanism of the chemopreventive effect of resveratrol
    • Z. Dong Molecular mechanism of the chemopreventive effect of resveratrol Mutat. Res. 523-524 2003 145 150
    • (2003) Mutat. Res. , vol.523-524 , pp. 145-150
    • Dong, Z.1
  • 15
    • 40549110991 scopus 로고    scopus 로고
    • Take a break - Resveratrol in action on DNA
    • S.A. Gatz, and L. Wiesmüller Take a break - resveratrol in action on DNA Carcinogenesis 29 2008 321 332
    • (2008) Carcinogenesis , vol.29 , pp. 321-332
    • Gatz, S.A.1    Wiesmüller, L.2
  • 16
    • 0037443604 scopus 로고    scopus 로고
    • Lithium inhibits Abeta-induced stress in endoplasmic reticulum of rabbit hippocampus but does not prevent oxidative damage and tau phosphorylation
    • O. Ghribi, M.M. Herman, and J. Savory Lithium inhibits Abeta-induced stress in endoplasmic reticulum of rabbit hippocampus but does not prevent oxidative damage and tau phosphorylation J. Neurosci. Res. 71 2003 853 862
    • (2003) J. Neurosci. Res. , vol.71 , pp. 853-862
    • Ghribi, O.1    Herman, M.M.2    Savory, J.3
  • 17
    • 0030856008 scopus 로고    scopus 로고
    • Vitamins C, e and A and heme oxygenase in rats fed methyl/folate- deficient diets
    • S.M. Henning, M.E. Swendseid, B.T. Ivandic, and F. Liao Vitamins C, E and A and heme oxygenase in rats fed methyl/folate-deficient diets Free Radical Biol. Med. 23 1997 936 942
    • (1997) Free Radical Biol. Med. , vol.23 , pp. 936-942
    • Henning, S.M.1    Swendseid, M.E.2    Ivandic, B.T.3    Liao, F.4
  • 18
    • 0033152949 scopus 로고    scopus 로고
    • Resveratrol increases nitric oxide synthase, induces accumulation of p53 and p21(WAF1/CIP1), and suppresses cultured bovine pulmonary artery endothelial cell proliferation by perturbing progression through S and G2
    • T.C. Hsieh, G. Juan, Z. Darzynkiewicz, and J.M. Wu Resveratrol increases nitric oxide synthase, induces accumulation of p53 and p21(WAF1/CIP1), and suppresses cultured bovine pulmonary artery endothelial cell proliferation by perturbing progression through S and G2 Cancer Res. 59 1999 2596 2601
    • (1999) Cancer Res. , vol.59 , pp. 2596-2601
    • Hsieh, T.C.1    Juan, G.2    Darzynkiewicz, Z.3    Wu, J.M.4
  • 19
    • 77957875108 scopus 로고    scopus 로고
    • Differential regulation of proliferation, cell cycle control and gene expression in cultured human aortic and pulmonary artery endothelial cells by resveratrol
    • T.C. Hsieh, X. Lu, J. Guo, and J.M. Wu Differential regulation of proliferation, cell cycle control and gene expression in cultured human aortic and pulmonary artery endothelial cells by resveratrol Int. J. Mol. Med. 26 2010 743 749
    • (2010) Int. J. Mol. Med. , vol.26 , pp. 743-749
    • Hsieh, T.C.1    Lu, X.2    Guo, J.3    Wu, J.M.4
  • 20
    • 0035182406 scopus 로고    scopus 로고
    • Folate depletion and elevated plasma homocysteine promote oxidative stress in rat livers
    • R.F. Huang, Y.C. Hsu, H.L. Lin, and F.L. Yang Folate depletion and elevated plasma homocysteine promote oxidative stress in rat livers J. Nutr. 131 2001 33 38
    • (2001) J. Nutr. , vol.131 , pp. 33-38
    • Huang, R.F.1    Hsu, Y.C.2    Lin, H.L.3    Yang, F.L.4
  • 21
  • 22
    • 4444257621 scopus 로고    scopus 로고
    • Inhibition of thrombin-induced signaling by resveratrol and quercetin: Effects on adenosine nucleotide metabolism in endothelial cells and platelet-neutrophil interactions
    • N.C. Kaneider, B. Mosheimer, N. Reinisch, J.R. Patsch, and C.J. Wiedermann Inhibition of thrombin-induced signaling by resveratrol and quercetin: effects on adenosine nucleotide metabolism in endothelial cells and platelet-neutrophil interactions Thromb. Res. 114 2004 185 194
    • (2004) Thromb. Res. , vol.114 , pp. 185-194
    • Kaneider, N.C.1    Mosheimer, B.2    Reinisch, N.3    Patsch, J.R.4    Wiedermann, C.J.5
  • 23
    • 60249098801 scopus 로고    scopus 로고
    • Dietary supplementation with resveratrol reduces plaque pathology in a transgenic model of Alzheimer's disease
    • S.S. Karuppagounder, J.T. Pinto, H. Xu, H.L. Chen, M.F. Beal, and G.E. Gibson Dietary supplementation with resveratrol reduces plaque pathology in a transgenic model of Alzheimer's disease Neurochem. Int. 54 2009 111 118
    • (2009) Neurochem. Int. , vol.54 , pp. 111-118
    • Karuppagounder, S.S.1    Pinto, J.T.2    Xu, H.3    Chen, H.L.4    Beal, M.F.5    Gibson, G.E.6
  • 27
    • 77952886659 scopus 로고    scopus 로고
    • Effects of maternal hyperhomocysteinemia induced by methionine intake on oxidative stress and apoptosis in pup rat brain
    • S.T. Koz, N.T. Gouwy, N. Demir, V.S. Nedzvetsky, E. Etem, and G. Baydas Effects of maternal hyperhomocysteinemia induced by methionine intake on oxidative stress and apoptosis in pup rat brain Int. J. Dev. Neurosci. 28 2010 325 329
    • (2010) Int. J. Dev. Neurosci. , vol.28 , pp. 325-329
    • Koz, S.T.1    Gouwy, N.T.2    Demir, N.3    Nedzvetsky, V.S.4    Etem, E.5    Baydas, G.6
  • 28
    • 84863728716 scopus 로고    scopus 로고
    • Gingko biloba extract inhibits oxidative stress and ameliorates impaired glial fibrillary acidic protein expression, but can not improve spatial learning in offspring from hyperhomocysteinemic rat dams
    • 10.1002/ptr.3669
    • S.T. Koz, G. Baydas, S. Koz, N. Demir, and V.S. Nedzvetsky Gingko biloba extract inhibits oxidative stress and ameliorates impaired glial fibrillary acidic protein expression, but can not improve spatial learning in offspring from hyperhomocysteinemic rat dams Phytother. Res. 2011 10.1002/ptr.3669
    • (2011) Phytother. Res.
    • Koz, S.T.1    Baydas, G.2    Koz, S.3    Demir, N.4    Nedzvetsky, V.S.5
  • 29
    • 0034666267 scopus 로고    scopus 로고
    • Homocysteine elicits a DNA damage response in neurons that promotes apoptosis and hypersensitivity to excitotoxicity
    • I.I. Kruman, C. Culmsee, S.L. Chan, Y. Kruman, Z. Guo, L. Penix, and M.P. Mattson Homocysteine elicits a DNA damage response in neurons that promotes apoptosis and hypersensitivity to excitotoxicity J. Neurosci. 20 2000 6920 6926
    • (2000) J. Neurosci. , vol.20 , pp. 6920-6926
    • Kruman, I.I.1    Culmsee, C.2    Chan, S.L.3    Kruman, Y.4    Guo, Z.5    Penix, L.6    Mattson, M.P.7
  • 30
    • 77950189559 scopus 로고    scopus 로고
    • NF-kappaB inhibitory action of resveratrol: A probable mechanism of neuroprotection in experimental diabetic neuropathy
    • A. Kumar, and S.S. Sharma NF-kappaB inhibitory action of resveratrol: a probable mechanism of neuroprotection in experimental diabetic neuropathy Biochem. Biophys. Res. Commun. 394 2010 360 365
    • (2010) Biochem. Biophys. Res. Commun. , vol.394 , pp. 360-365
    • Kumar, A.1    Sharma, S.S.2
  • 31
    • 20044391979 scopus 로고    scopus 로고
    • Nitric oxide inhibition of homocysteine-induced human endothelial cell apoptosis by down-regulation of p53-dependent Noxa expression through the formation of S-nitrosohomocysteine
    • S.J. Lee, K.M. Kim, S. Namkoong, C.K. Kim, Y.C. Kang, H. Lee, K.S. Ha, J.A. Han, H.T. Chung, Y.G. Kwon, and Y.M. Kim Nitric oxide inhibition of homocysteine-induced human endothelial cell apoptosis by down-regulation of p53-dependent Noxa expression through the formation of S-nitrosohomocysteine J. Biol. Chem. 280 2005 5781 5788
    • (2005) J. Biol. Chem. , vol.280 , pp. 5781-5788
    • Lee, S.J.1    Kim, K.M.2    Namkoong, S.3    Kim, C.K.4    Kang, Y.C.5    Lee, H.6    Ha, K.S.7    Han, J.A.8    Chung, H.T.9    Kwon, Y.G.10    Kim, Y.M.11
  • 34
    • 28744448389 scopus 로고    scopus 로고
    • Mitochondrial damage induced by fetal hyperphenylalaninemia in the rat brain and liver: Its prevention by melatonin, vitamin E, and vitamin C
    • F. Martinez-Cruz, C. Osuna, and J.M. Guerrero Mitochondrial damage induced by fetal hyperphenylalaninemia in the rat brain and liver: its prevention by melatonin, vitamin E, and vitamin C Neurosci. Lett. 392 2006 1 4
    • (2006) Neurosci. Lett. , vol.392 , pp. 1-4
    • Martinez-Cruz, F.1    Osuna, C.2    Guerrero, J.M.3
  • 35
    • 79956039762 scopus 로고    scopus 로고
    • Response of blood platelets to resveratrol during a model of hyperhomocysteinemia
    • J. Malinowska, and B. Olas Response of blood platelets to resveratrol during a model of hyperhomocysteinemia Platelets 22 2011 277 283
    • (2011) Platelets , vol.22 , pp. 277-283
    • Malinowska, J.1    Olas, B.2
  • 37
    • 34248146970 scopus 로고    scopus 로고
    • Effect of resveratrol on antioxidant enzyme activities in the brain of healthy rat
    • M. Mokni, S. Elkahoui, F. Limam, M. Amri, and E. Aouani Effect of resveratrol on antioxidant enzyme activities in the brain of healthy rat Neurochem. Res. 32 2007 981 987
    • (2007) Neurochem. Res. , vol.32 , pp. 981-987
    • Mokni, M.1    Elkahoui, S.2    Limam, F.3    Amri, M.4    Aouani, E.5
  • 38
    • 33845735068 scopus 로고    scopus 로고
    • Strong cardioprotective effect of resveratrol, a red wine polyphenol, on isolated rat hearts after ischemia/reperfusion injury
    • M. Mokni, F. Limam, S. Elkahoui, M. Amri, and E. Aouani Strong cardioprotective effect of resveratrol, a red wine polyphenol, on isolated rat hearts after ischemia/reperfusion injury Arch. Biochem. Biophys. 457 2007 1 6
    • (2007) Arch. Biochem. Biophys. , vol.457 , pp. 1-6
    • Mokni, M.1    Limam, F.2    Elkahoui, S.3    Amri, M.4    Aouani, E.5
  • 39
    • 79952324401 scopus 로고    scopus 로고
    • Resveratrol improves hippocampal atrophy in chronic fatigue mice by enhancing neurogenesis and inhibiting apoptosis of granular cells
    • J. Moriya, R. Chen, J. Yamakawa, K. Sasaki, Y. Ishigaki, and T. Takahashi Resveratrol improves hippocampal atrophy in chronic fatigue mice by enhancing neurogenesis and inhibiting apoptosis of granular cells Biol. Pharm. Bull. 34 2011 354 359
    • (2011) Biol. Pharm. Bull. , vol.34 , pp. 354-359
    • Moriya, J.1    Chen, R.2    Yamakawa, J.3    Sasaki, K.4    Ishigaki, Y.5    Takahashi, T.6
  • 40
    • 0019957779 scopus 로고
    • Place navigation impaired in rats with hippocampal lesions
    • R.G. Morris, P. Garrud, J.N. Rawlins, and J. O'Keefe Place navigation impaired in rats with hippocampal lesions Nature 297 1982 681 683
    • (1982) Nature , vol.297 , pp. 681-683
    • Morris, R.G.1    Garrud, P.2    Rawlins, J.N.3    O'Keefe, J.4
  • 41
    • 50149097809 scopus 로고    scopus 로고
    • A complex barcode underlies the heterogeneous response of p53 to stress
    • F. Murray-Zmijewski, E.A. Slee, and X. Lu A complex barcode underlies the heterogeneous response of p53 to stress Nat. Rev. Mol. Cell Biol. 9 2008 702 712
    • (2008) Nat. Rev. Mol. Cell Biol. , vol.9 , pp. 702-712
    • Murray-Zmijewski, F.1    Slee, E.A.2    Lu, X.3
  • 42
    • 77953050012 scopus 로고    scopus 로고
    • Physiological concentrations of dietary polyphenols regulate vascular endothelial cell expression of genes important in cardiovascular health
    • S.K. Nicholson, G.A. Tucker, and J.M. Brameld Physiological concentrations of dietary polyphenols regulate vascular endothelial cell expression of genes important in cardiovascular health Br. J. Nutr. 103 2010 1398 1403
    • (2010) Br. J. Nutr. , vol.103 , pp. 1398-1403
    • Nicholson, S.K.1    Tucker, G.A.2    Brameld, J.M.3
  • 43
    • 58149279278 scopus 로고    scopus 로고
    • Resveratrol supplementation worsen the dysregulation of genes involved in hepatic lipid homeostasis observed in hyperhomocysteinemic mice
    • C. Noll, J. Hamelet, V. Ducros, N. Belin, J.L. Paul, J.M. Delabar, and N. Janel Resveratrol supplementation worsen the dysregulation of genes involved in hepatic lipid homeostasis observed in hyperhomocysteinemic mice Food Chem. Toxicol. 47 2009 230 236
    • (2009) Food Chem. Toxicol. , vol.47 , pp. 230-236
    • Noll, C.1    Hamelet, J.2    Ducros, V.3    Belin, N.4    Paul, J.L.5    Delabar, J.M.6    Janel, N.7
  • 44
    • 33845942205 scopus 로고    scopus 로고
    • Resveratrol protects dopaminergic neurons in midbrain slice culture from multiple insults
    • M. Okawara, H. Katsuki, E. Kurimoto, H. Shibata, T. Kume, and A. Akaike Resveratrol protects dopaminergic neurons in midbrain slice culture from multiple insults Biochem. Pharmacol. 73 2007 550 560
    • (2007) Biochem. Pharmacol. , vol.73 , pp. 550-560
    • Okawara, M.1    Katsuki, H.2    Kurimoto, E.3    Shibata, H.4    Kume, T.5    Akaike, A.6
  • 45
    • 29144534694 scopus 로고    scopus 로고
    • Resveratrol inhibits vascular smooth muscle cell proliferation and induces apoptosis
    • B. Poussier, A.C. Cordova, J.P. Becquemin, and B.E. Sumpio Resveratrol inhibits vascular smooth muscle cell proliferation and induces apoptosis J. Vasc. Surg. 42 2005 1190 1197
    • (2005) J. Vasc. Surg. , vol.42 , pp. 1190-1197
    • Poussier, B.1    Cordova, A.C.2    Becquemin, J.P.3    Sumpio, B.E.4
  • 46
    • 68449083925 scopus 로고    scopus 로고
    • Resveratrol protects spatial learning in middle-aged C57BL/6 mice from effects of ethanol
    • A. Ranney, and M.S. Petro Resveratrol protects spatial learning in middle-aged C57BL/6 mice from effects of ethanol Behav. Pharmacol. 20 2009 330 336
    • (2009) Behav. Pharmacol. , vol.20 , pp. 330-336
    • Ranney, A.1    Petro, M.S.2
  • 48
    • 60949087943 scopus 로고    scopus 로고
    • Long-term resveratrol administration reduces metabolic disturbances and lowers blood pressure in obese Zucker rats
    • L. Rivera, R. Morón, A. Zarzuelo, and M. Galisteo Long-term resveratrol administration reduces metabolic disturbances and lowers blood pressure in obese Zucker rats Biochem. Pharmacol. 77 2009 1053 1063
    • (2009) Biochem. Pharmacol. , vol.77 , pp. 1053-1063
    • Rivera, L.1    Morón, R.2    Zarzuelo, A.3    Galisteo, M.4
  • 50
    • 0035695652 scopus 로고    scopus 로고
    • Induction of endothelin-1 expression by oxidative stress in vascular smooth muscle cells
    • J. Ruef, M. Moser, W. Kübler, and C. Bode Induction of endothelin-1 expression by oxidative stress in vascular smooth muscle cells Cardiovasc. Pathol. 10 2001 311 315
    • (2001) Cardiovasc. Pathol. , vol.10 , pp. 311-315
    • Ruef, J.1    Moser, M.2    Kübler, W.3    Bode, C.4
  • 51
    • 77953711040 scopus 로고    scopus 로고
    • Resveratrol protects against experimental stroke: Putative neuroprotective role of heme oxygenase 1
    • Y. Sakata, H. Zhuang, H. Kwansa, R.C. Koehler, and S. Dore Resveratrol protects against experimental stroke: putative neuroprotective role of heme oxygenase 1 Exp. Neurol. 224 2010 325 329
    • (2010) Exp. Neurol. , vol.224 , pp. 325-329
    • Sakata, Y.1    Zhuang, H.2    Kwansa, H.3    Koehler, R.C.4    Dore, S.5
  • 53
    • 27744537688 scopus 로고    scopus 로고
    • Anti-inflammatory compound resveratrol suppresses homocysteine formation in stimulated human peripheral blood mononuclear cells in vitro
    • K. Schroecksnadel, C. Winkler, B. Wirleitner, H. Schennach, G. Weiss, and D. Fuchs Anti-inflammatory compound resveratrol suppresses homocysteine formation in stimulated human peripheral blood mononuclear cells in vitro Clin. Chem. Lab. Med. 43 2005 1084 1088
    • (2005) Clin. Chem. Lab. Med. , vol.43 , pp. 1084-1088
    • Schroecksnadel, K.1    Winkler, C.2    Wirleitner, B.3    Schennach, H.4    Weiss, G.5    Fuchs, D.6
  • 54
    • 34848900430 scopus 로고    scopus 로고
    • Inhibitory mechanisms of resveratrol in platelet activation: Pivotal roles of p38 MAPK and NO/cyclic GMP
    • M.Y. Shen, G. Hsiao, C.L. Liu, T.H. Fong, K.H. Lin, D.S. Chou, and J.R. Sheu Inhibitory mechanisms of resveratrol in platelet activation: pivotal roles of p38 MAPK and NO/cyclic GMP Br. J. Haematol. 139 2007 475 485
    • (2007) Br. J. Haematol. , vol.139 , pp. 475-485
    • Shen, M.Y.1    Hsiao, G.2    Liu, C.L.3    Fong, T.H.4    Lin, K.H.5    Chou, D.S.6    Sheu, J.R.7
  • 55
    • 77953956124 scopus 로고    scopus 로고
    • Resveratrol attenuates behavioral impairments and reduces cortical and hippocampal loss in a rat controlled cortical impact model of traumatic brain injury
    • R.H. Singleton, H.Q. Yan, W. Fellows-Mayle, and C.E. Dixon Resveratrol attenuates behavioral impairments and reduces cortical and hippocampal loss in a rat controlled cortical impact model of traumatic brain injury J. Neurotrauma 27 2010 1091 1099
    • (2010) J. Neurotrauma , vol.27 , pp. 1091-1099
    • Singleton, R.H.1    Yan, H.Q.2    Fellows-Mayle, W.3    Dixon, C.E.4
  • 56
    • 0037189154 scopus 로고    scopus 로고
    • Protective effect of resveratrol against oxidative stress in middle cerebral artery occlusion model of stroke in rats
    • K. Sinha, G. Chaudhary, and Y.K. Gupta Protective effect of resveratrol against oxidative stress in middle cerebral artery occlusion model of stroke in rats Life Sci. 71 2002 655 665
    • (2002) Life Sci. , vol.71 , pp. 655-665
    • Sinha, K.1    Chaudhary, G.2    Gupta, Y.K.3
  • 58
    • 77951684623 scopus 로고    scopus 로고
    • Signal transduction by protease-activated receptors
    • U.J. Soh, M.R. Dores, B. Chen, and J. Trejo Signal transduction by protease-activated receptors Br. J. Pharmacol. 160 2010 191 203
    • (2010) Br. J. Pharmacol. , vol.160 , pp. 191-203
    • Soh, U.J.1    Dores, M.R.2    Chen, B.3    Trejo, J.4
  • 59
    • 0030963473 scopus 로고    scopus 로고
    • Resveratrol: A molecule whose time has come? and gone?
    • G.J. Soleas, E.P. Diamandis, and D.M. Goldberg Resveratrol: a molecule whose time has come? And gone? Clin. Biochem. 30 1997 91 113
    • (1997) Clin. Biochem. , vol.30 , pp. 91-113
    • Soleas, G.J.1    Diamandis, E.P.2    Goldberg, D.M.3
  • 60
    • 34249321307 scopus 로고    scopus 로고
    • Neuroprotective effects of resveratrol against traumatic brain injury in immature rats
    • U. Sönmez, A. Sönmez, G. Erbil, I. Tekmen, and B. Baykara Neuroprotective effects of resveratrol against traumatic brain injury in immature rats Neurosci. Lett. 420 2007 133 137
    • (2007) Neurosci. Lett. , vol.420 , pp. 133-137
    • Sönmez, U.1    Sönmez, A.2    Erbil, G.3    Tekmen, I.4    Baykara, B.5
  • 62
    • 3242676904 scopus 로고    scopus 로고
    • Chronic hyperhomocysteinemia provokes a memory deficit in rats in the Morris water maze task
    • E.L. Streck, C.S. Bavaresco, C.A. Netto, and A.T. Wyse Chronic hyperhomocysteinemia provokes a memory deficit in rats in the Morris water maze task Behav. Brain Res. 153 2004 377 381
    • (2004) Behav. Brain Res. , vol.153 , pp. 377-381
    • Streck, E.L.1    Bavaresco, C.S.2    Netto, C.A.3    Wyse, A.T.4
  • 63
    • 34547115974 scopus 로고    scopus 로고
    • Resveratrol neuroprotective effects during focal cerebral ischemia injury via nitric oxide mechanism in rats
    • S.K. Tsai, L.M. Hung, Y.T. Fu, H. Cheng, M.W. Nien, H.Y. Liu, F.B. Zhang, and S.S. Huang Resveratrol neuroprotective effects during focal cerebral ischemia injury via nitric oxide mechanism in rats J. Vasc. Surg. 46 2007 346 353
    • (2007) J. Vasc. Surg. , vol.46 , pp. 346-353
    • Tsai, S.K.1    Hung, L.M.2    Fu, Y.T.3    Cheng, H.4    Nien, M.W.5    Liu, H.Y.6    Zhang, F.B.7    Huang, S.S.8
  • 66
    • 0037167677 scopus 로고    scopus 로고
    • Resveratrol, a polyphenolic phytoalexin present in red wine, enhances expression and activity of endothelial nitric oxide synthase
    • T. Wallerath, G. Deckert, T. Ternes, H. Anderson, H. Li, K. Witte, and U. Förstermann Resveratrol, a polyphenolic phytoalexin present in red wine, enhances expression and activity of endothelial nitric oxide synthase Circulation 106 2002 1652 1658
    • (2002) Circulation , vol.106 , pp. 1652-1658
    • Wallerath, T.1    Deckert, G.2    Ternes, T.3    Anderson, H.4    Li, H.5    Witte, K.6    Förstermann, U.7
  • 67
    • 0242516020 scopus 로고    scopus 로고
    • 2 and NO on apoptosis involving activation of p38 mitogen-activated protein kinase and caspase-3
    • 2 and NO on apoptosis involving activation of p38 mitogen-activated protein kinase and caspase-3 J. Neurosci. Res. 72 2003 508 519
    • (2003) J. Neurosci. Res. , vol.72 , pp. 508-519
    • Wang, J.Y.1    Shum, A.Y.2    Ho, Y.J.3    Wang, J.Y.4
  • 69
    • 0035863857 scopus 로고    scopus 로고
    • Different effects of genistein and resveratrol on oxidative DNA damage in vitro
    • W. Win, Z. Cao, X. Peng, M.A. Trush, and Y. Li Different effects of genistein and resveratrol on oxidative DNA damage in vitro Mutat. Res. 513 2002 113 120
    • (2002) Mutat. Res. , vol.513 , pp. 113-120
    • Win, W.1    Cao, Z.2    Peng, X.3    Trush, M.A.4    Li, Y.5
  • 70
    • 39649090942 scopus 로고    scopus 로고
    • Resveratrol attenuates thromboxane A2 receptor agonist-induced platelet activation by reducing phospholipase C activity
    • Y.M. Yang, J.Z. Chen, X.X. Wang, S.J. Wang, H. Hu, and H.Q. Wang Resveratrol attenuates thromboxane A2 receptor agonist-induced platelet activation by reducing phospholipase C activity Eur. J. Pharmacol. 583 2008 148 155
    • (2008) Eur. J. Pharmacol. , vol.583 , pp. 148-155
    • Yang, Y.M.1    Chen, J.Z.2    Wang, X.X.3    Wang, S.J.4    Hu, H.5    Wang, H.Q.6
  • 71
    • 58149279285 scopus 로고    scopus 로고
    • Resveratrol exerts its neuroprotective effect by modulating mitochondrial dysfunctions and associated cell death during cerebral ischemia
    • S. Yousuf, F. Atif, M. Ahmad, N. Hoda, T. Ishrat, B. Khan, and F. Islam Resveratrol exerts its neuroprotective effect by modulating mitochondrial dysfunctions and associated cell death during cerebral ischemia Brain Res. 1250 2009 242 253
    • (2009) Brain Res. , vol.1250 , pp. 242-253
    • Yousuf, S.1    Atif, F.2    Ahmad, M.3    Hoda, N.4    Ishrat, T.5    Khan, B.6    Islam, F.7
  • 72
    • 79957532361 scopus 로고    scopus 로고
    • Resveratrol attenuates doxorubicin-induced cardiomyocyte apoptosis in mice through SIRT1-mediated deacetylation of p53
    • C. Zhang, Y. Feng, S. Qu, X. Wei, H. Zhu, Q. Luo, M. Liu, G. Chen, and X. Xiao Resveratrol attenuates doxorubicin-induced cardiomyocyte apoptosis in mice through SIRT1-mediated deacetylation of p53 Cardiovasc. Res. 90 2011 538 545
    • (2011) Cardiovasc. Res. , vol.90 , pp. 538-545
    • Zhang, C.1    Feng, Y.2    Qu, S.3    Wei, X.4    Zhu, H.5    Luo, Q.6    Liu, M.7    Chen, G.8    Xiao, X.9
  • 73
    • 68149150584 scopus 로고    scopus 로고
    • Resveratrol improves endothelial function: Role of TNF{alpha} and vascular oxidative stress
    • H. Zhang, J. Zhang, Z. Ungvari, and C. Zhang Resveratrol improves endothelial function: role of TNF{alpha} and vascular oxidative stress Arterioscler Thromb. Vasc. Biol. 29 2009 1164 1171
    • (2009) Arterioscler Thromb. Vasc. Biol. , vol.29 , pp. 1164-1171
    • Zhang, H.1    Zhang, J.2    Ungvari, Z.3    Zhang, C.4
  • 74
    • 82955205728 scopus 로고    scopus 로고
    • Interaction between resveratrol and thrombin and its biological implication
    • J. Zhang, W.J. Yu, N. Yang, and L. Sun Interaction between resveratrol and thrombin and its biological implication Int. J. Food Sci. Nutr. 62 2011 814 820
    • (2011) Int. J. Food Sci. Nutr. , vol.62 , pp. 814-820
    • Zhang, J.1    Yu, W.J.2    Yang, N.3    Sun, L.4
  • 75
    • 0034548869 scopus 로고    scopus 로고
    • Effect of resveratrol on intimal hyperplasia after endothelial denudation in an experimental rabbit model
    • J. Zou, Y. Huang, K. Cao, G. Yang, H. Yin, J. Len, T.C. Hsieh, and J.M. Wu Effect of resveratrol on intimal hyperplasia after endothelial denudation in an experimental rabbit model Life Sci. 68 2000 153 163
    • (2000) Life Sci. , vol.68 , pp. 153-163
    • Zou, J.1    Huang, Y.2    Cao, K.3    Yang, G.4    Yin, H.5    Len, J.6    Hsieh, T.C.7    Wu, J.M.8
  • 76
    • 0042773944 scopus 로고    scopus 로고
    • Effect of red wine and wine polyphenol resveratrol on endothelial function in hypercholesterolemic rabbits
    • J.G. Zou, Z.R. Wang, Y.Z. Huang, K.J. Cao, and J.M. Wu Effect of red wine and wine polyphenol resveratrol on endothelial function in hypercholesterolemic rabbits Int. J. Mol. Med. 11 2003 317 320
    • (2003) Int. J. Mol. Med. , vol.11 , pp. 317-320
    • Zou, J.G.1    Wang, Z.R.2    Huang, Y.Z.3    Cao, K.J.4    Wu, J.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.