Directing cell motions on micropatterned ratchets

Nature Physics

Volumn 5, Issue 8, 2009, Pages 606-612

  Mahmud, Goher ^a   Campbell, Christopher J ^a   Bishop, Kyle J M ^a   Komarova, Yulia A ^a   Chaga, Oleg ^a   Soh, Siowling ^a   Huda, Sabil ^a   Kandere Grzybowska, Kristiana ^a   Grzybowski, Bartosz A ^a  

^a Northwestern University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; CELL PROLIFERATION; PHYSIOLOGICAL MODELS;

CELL MIGRATION; CELL MOTILITY; CELL POLARIZATION; CYTOSKELETONS; ENVIRONMENTAL CUES; MICRO GEOMETRY; MICROPATTERNED; RANDOM MOTIONS;

CELLS;

EID: 68749083308     PISSN: 17452473     EISSN: 17452481     Source Type: Journal    
DOI: 10.1038/nphys1306     Document Type: Article

References (49)

1. Lee, S. H. & Grier, D. G. One-dimensional optical thermal ratchets. J. Phys. Condens. Matter 17, S3685-S3695 (2005).
2. Lee, C. S., Janko, B., Derenyi, I. & Barabasi, A. L. Reducing vortex density in superconductors using the 'ratchet effect'. Nature 400, 337-340 (1999).
3. Lorke, A. et al. Far-infrared and transport properties of antidot arrays with broken symmetry. Physica B 251, 312-316 (1998).
4. Rousselet, J., Salome, L., Ajdari, A. & Prost, J. Directional motion of Brownian particles induced by a periodic asymmetric potential. Nature 370, 446-448 (1994).
5. Engel, A., Muller, H. W., Reimann, P. & Jung, A. Ferrofluids as thermal ratchets. Phys. Rev. Lett. 91, 060602 (2003).
6. Linke, H. et al. Experimental tunneling ratchets. Science 286, 2314-2317 (1999).
7. van Oudenaarden, A. & Boxer, S. G. Brownian ratchets: Molecular separations in lipid bilayers supported on patterned arrays. Science 285, 1046-1048 (1999).
8. Villegas, J. E. et al. A superconducting reversible rectifier that controls the motion of magnetic flux quanta. Science 302, 1188-1191 (2003).
9. Hiratsuka, Y., Tada, T., Oiwa, K., Kanayama, T. & Uyeda, T. Q. P. Controlling the direction of kinesin-driven microtubule movements along microlithographic tracks. Biophys. J. 81, 1555-1561 (2001).
10. Matthias, S. & Muller, F. Asymmetric pores in a silicon membrane acting as massively parallel Brownian ratchets. Nature 424, 53-57 (2003).
11. Reimann, P. Brownian motors: Noisy transport far from equilibrium. Phys. Rep.-Rev. Sec. Phys. Lett. 361, 57-265 (2002).
12. Astumian, R. D. & Hanggi, P. Brownian motors. Phys. Today 55, 33-39 (2002).
13. Feynman, R. P., Leighton, R. B. & Sands, M. L. The Feynman Lectures on Physics Vol. 1 (Pearson/Addison-Wesley, 2006).
14. Peskin, C. S., Odell, G. M. & Oster, G. F. Cellular motions and thermal fluctuations - the Brownian ratchet. Biophys. J. 65, 316-324 (1993).
15. Silva, C. C. D., de Vondel, J. V., Morelle, M. & Moshchalkov, V. V. Controlled multiple reversals of a ratchet effect. Nature 440, 651-654 (2006).
16. Kelly, T. R., De Silva, H. & Silva, R. A. Unidirectional rotary motion in a molecular system. Nature 401, 150-152 (1999).
17. Simon, S. M., Peskin, C. S. & Oster, G. F. What drives the translocation of proteins. Proc. Natl Acad. Sci. USA 89, 3770-3774 (1992).
18. Alt, W. Biased random-walk models for chemotaxis and related diffusion approximations. J. Math. Biol. 9, 147-177 (1980).
19. Dunn, G. A. & Brown, A. F. A unified approach to analyzing cell motility. J. Cell Sci. Suppl. 8, 81-102 (1987).
20. Theriot, J. A. & Mitchison, T. J. Actin microfilament dynamics in locomoting cells. Nature 352, 126-131 (1991).
21. Ponti, A., Machacek, M., Gupton, S. L., Waterman-Storer, C. M. & Danuser, G. Two distinct actin networks drive the protrusion of migrating cells. Science 305, 1782-1786 (2004).
22. Thery, M. et al. Anisotropy of cell adhesive microenvironment governs cell internal organization and orientation of polarity. Proc. Natl Acad. Sci. USA 103, 19771-19776 (2006).
23. Thery, M., Pepin, A., Dressaire, E., Chen, Y. & Bornens, M. Cell distribution of stress fibres in response to the geometry of the adhesive environment. Cell Motil. Cytoskeleton 63, 341-355 (2006).
24. Jiang, X. Y. et al. A general method for patterning gradients of biomolecules on surfaces using microfluidic networks. Anal. Chem. 77, 2338-2347 (2005).
25. Dertinger, S. K. W., Jiang, X. Y., Li, Z. Y., Murthy, V. N. & Whitesides, G. M. Gradients of substrate-bound laminin orient axonal specification of neurons. Proc. Natl Acad. Sci. USA 99, 12542-12547 (2002).
26. Brandley, B. K. & Schnaar, R. L. Tumor-cell haptotaxis on covalently immobilized linear and exponential gradients of a cell-adhesion peptide. Dev. Biol. 135, 74-86 (1989).
27. Smith, J. T. et al. Measurement of cell migration on surface-bound fibronectin gradients. Langmuir 20, 8279-8286 (2004).
28. Plummer, S. T., Wang, Q., Bohn, P. W., Stockton, R. & Schwartz, M. A. Electrochemically derived gradients of the extracellular matrix protein fibronectin on gold. Langmuir 19, 7528-7536 (2003).
29. Campbell, C. J., Smoukov, S. K., Bishop, K. J. M., Baker, E. & Grzybowski, B. A. Direct printing of 3d and curvilinear micrometer-sized architectures into solid substrates with sub-micrometer resolution. Adv. Mater. 18, 2004-2008 (2006).
30. Kandere-Grzybowska, K., Campbell, C., Komarova, Y., Grzybowski, B. A. & Borisy, G. G. Molecular dynamics imaging in micropatterned living cells. Nature Meth. 2, 739-741 (2005).
31. Maroudas, N. G. Polymer exclusion, cell adhesion and membrane-fusion. Nature 254, 695-696 (1975).
32. Prime, K. L. & Whitesides, G. M. Self-assembled organic monolayers - model systems for studying adsorption of proteins at surfaces. Science 252, 1164-1167 (1991).
33. Singhvi, R. et al. Engineering cell-shape and function. Science 264, 696-698 (1994).
34. Kandere-Grzybowska, K. et al. Cell motility on micropatterned treadmills and tracks. Soft Matter 3, 672-679 (2007).
35. Jiang, X. Y., Bruzewicz, D. A., Wong, A. P., Piel, M. & Whitesides, G. M. Directing cell migration with asymmetric micropatterns. Proc. Natl Acad. Sci. USA 102, 975-978 (2005).
36. Groisman, A. & Quake, S. R. A microfluidic rectifier: Anisotropic flow resistance at low reynolds numbers. Phys. Rev. Lett. 92, 094501 (2004).
37. Grazi, E., Cintio, O. & Trombetta, G. On the mechanics of the actin filament: The linear relationship between stiffness and yield strength allows estimation of the yield strength of thin filament in vivo. J. Muscle Res. Cell Motil. 25, 103-105 (2004).
38. Brown, C. M. et al. Probing the integrin-actin linkage using high-resolution protein velocity mapping. J. Cell Sci. 119, 5204-5214 (2006).
39. Thatcher, A. R. Studies in the history of probability and statistics vi. A note on the early solutions of the problem of the duration of play. Biometrika 44, 515-518 (1957).
40. Kumar, A., Galaev, I. Y. & Mattiasson, B. (eds) Cell Separation: Fundamentals, Analytical and Preparative Methods Vol. 106 (Springer, 2007).
41. Steinberg, M. S. & Takeichi, M. Experimental specification of cell sorting, tissue spreading, and specific spatial patterning by quantitative differences in cadherin expression. Proc. Natl Acad. Sci. USA 91, 206-209 (1994).
42. Xu, Q. L., Mellitzer, G., Robinson, V. & Wilkinson, D. G. In vivo cell sorting in complementary segmental domains mediated by eph receptors and ephrins. Nature 399, 267-271 (1999).
43. Keren, D. F., McCoy, J. P. & Carey, J. L. Flow Cytometry in Clinical Diagnosis 3rd edn (American Society Clinical Pathology, 2001).
44. Jennings, C. D. & Foon, K. A. Recent advances in flow cytometry: Application to the diagnosis of hematologic malignancy. Blood 90, 2863-2892 (1997).
45. Steinberg, M. S. Reconstruction of tissues by dissociated cells. Science 141, 401-408 (1963).
46. Townes, P. L. & Holtfreter, J. Directed movements and selective adhesion of embryonic amphibian cells. J. Exp. Zool. 128, 53-120 (1955).
47. Discher, D. E., Janmey, P. & Wang, Y. L. Tissue cells feel and respond to the stiffness of their substrate. Science 310, 1139-1143 (2005).
48. Wyckoff, J. B., Segall, J. E. & Condeelis, J. S. The collection of the motile population of cells from a living tumor. Cancer Res. 60, 5401-5404 (2000).
49. Gail, M. H. & Boone, C. W. Locomotion of mouse fibroblasts in tissue culture. Biophys. J. 10, 980-993 (1970).