Oleuropein, chief constituent of olive leaf extract, prevents the development of morphine antinociceptive tolerance through inhibition of morphine-induced l-type calcium channel overexpression

Phytotherapy Research

Volumn 26, Issue 11, 2012, Pages 1731-1737

  Zare, Leila ^a   Esmaeili Mahani, Saeed ^a   Abbasnejad, Mehdi ^a   Rasoulian, Bahram ^b   Sheibani, Vahid ^c   Sahraei, Hedayat ^d   Kaeidi, Ayat ^b  

^a SHAHID BAHONAR UNIVERSITY OF KERMAN   (Iran)

^b LORESTAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c KERMAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^d BAQIYATALLAH UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

calcium channel; morphine antinociception; oleuropein; olive leaf extract; rats; tolerance

Indexed keywords

ALCOHOL; CALCIUM CHANNEL L TYPE; MESSENGER RNA; MORPHINE; OLEUROPEIN; OLIVE EXTRACT; PLANT EXTRACT; UNCLASSIFIED DRUG;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTINOCICEPTION; ANTITOLERANT EFFECT; ARTICLE; CONTROLLED STUDY; DRUG DOSE COMPARISON; DRUG EFFECT; DRUG EFFICACY; DRUG TOLERANCE; EVENING DOSAGE; GENE EXPRESSION; INHIBITION KINETICS; LUMBAR SPINAL CORD; MALE; MORNING DOSAGE; NONHUMAN; NUCLEOTIDE SEQUENCE; OLIVE; PAIN THRESHOLD; PHYTOCHEMISTRY; PLANT LEAF; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TAIL FLICK TEST; TREATMENT DURATION;

ANALGESICS, OPIOID; ANIMALS; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS, L-TYPE; DRUG TOLERANCE; MALE; MORPHINE; OLEA; PAIN MEASUREMENT; PLANT EXTRACTS; PYRANS; RATS; RATS, WISTAR;

ANIMALIA; RATTUS; RATTUS NORVEGICUS;

EID: 84867869052     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.4634     Document Type: Article

References (39)

1. Abdel-Zaher AO, Abdel-Rahman MS, ELwasei FM,. 2010. Blockade of nitric oxide overproduction and oxidative stress by Nigella sativa oil attenuates morphine-induced tolerance and dependence in mice. Neurochem Res 35: 1557-1565.
2. Antkiewicz-Michaluk L, Michaluk J, Romanska I, Vetulani J,. 1993. Reduction in morphine dependence and potentiation of the analgesia by chronic coadministration of nifedipine. Psychopharmacology (Berl) 111: 457-464.
3. Briante R, Patumi M, Terenziani S, Bismuto E, Febbraio F, Nucci R,. 2002. Olea europaea L. leaf extract and derivatives: antioxidant properties. J Agric Food Chem 50: 4934-4940.
4. D'Amour FE, Smith DL,. 1941. A method of determining loss of pain sensation. J Pharmacol Exp Ther 27: 74-79.
5. Diaz A, Florez J, Pazos A, Hurle MA,. 2000. Opioid tolerance and supersensitivity induce regional changes in the autoradiographic density of dihydropyridine-sensitive calcium channels in the rat central nervous system. Pain 86: 227-235.
6. 2+ channels during opioid tolerance and supersensitivity in rats. J Pharmacol Exp Ther 274: 1538-1544.
7. Dogrul A, Bilsky EJ, Ossipov MH, Lai J, Porreca F,. 2005. Spinal L-type calcium channel blockade abolishes opioid-induced sensory hypersensitivity and antinociceptive tolerance. Anesth Analg 101: 1730-1735.
8. Dogrul A, Zagli U, Tulunay FC,. 2002. The role of T-type calcium channels in morphine analgesia, development of antinociceptive tolerance and dependence to morphine, and morphine abstinence syndrome. Life Sci 71: 725-734.
9. Doyle T, Bryant L, Batinic-Haberle I, et al,. 2009. Supraspinal inactivation of mitochondrial superoxide dismutase is a source of peroxynitrite in the development of morphine antinociceptive tolerance. Neuroscience 164: 702-710.
10. El SN, Karakaya S,. 2009. Olive tree (Olea europaea) leaves: potential beneficial effects on human health. Nutr Rev 67: 632-638.
11. Esmaeili-Mahani S, Fathi Y, Motamedi F, Hossein-Panah F, Ahmadiani A,. 2008. L-type calcium channel blockade attenuates morphine withdrawal: in vivo interaction between L-type calcium channels and corticosterone. Horm Behav 53: 351-357.
12. Esmaeili-Mahani S, Motamedi F, Javan M, Ahmadiani A,. 2005. Involvement of hypothalamic pituitary adrenal axis on the effects of nifedipine in the development of morphine tolerance in rats. Pharmacol Biochem Behav 81: 152-157.
13. Esmaeili-Mahani S, Rezaeezadeh-Roukerd M, Esmaeilpour K, et al,. 2010. Olive (Olea europaea L.) leaf extract elicits antinociceptive activity, potentiates morphine analgesia and suppresses morphine hyperalgesia in rats. J Ethnopharmacol 132: 200-205.
14. Farag RS, El-Baroty GS, Basuny AM,. 2003. Safety evaluation of olive phenolic compounds as natural antioxidants. Int J Food Sci Nutr 4: 159-174.
15. Gilani AH, Khan A, Shah AJ, Connor J, Jabeen Q,. 2005. Blood pressure lowering effect of olive is mediated through calcium channel blockade. Int J Food Sci Nutr 56: 613-620.
16. Hajializadeh Z, Esmaeili-Mahani S, Sheibani V, Kaeidi A, Atapour M, Abbasnejad M,. 2010. Changes in the gene expression of specific G-protein subunits correlate with morphine insensitivity in streptozotocin-induced diabetic rats. Neuropeptides 44: 299-304.
17. Haller VL, Bernstein MA, Welch SP,. 2008. Chronic morphine treatment decreases the Cav1.3 subunit of the L-type calcium channel. Eur J Pharmacol 578: 101-107.
18. Hashemi P, Delfan B, Ghiasvand AR, Alborzi M, Raeisi F,. 2010. A study of the effects of cultivation variety, collection time and climate on the level of oleuropein in olive leaves. Acta Chromatogr 22: 131-138.
19. 2+ channels in neuroblastoma cells: involvement of the orphan opioid receptor. Eur J Pharmacol 379: 191-198.
20. King T, Ossipov MH, Vanderah TW, Porreca F, Lai J,. 2005. Is paradoxical pain induced by sustained opioid exposure an underlying mechanism of opioid antinociceptive tolerance? Neurosignals 14: 194-205.
21. Kiritsakis K, Kontominas MG, Kontogiorgis C, Hadjipavlou-Litina D, Moustakas A, Kiritsakis A,. 2010. Composition and antioxidant activity of olive leaf extracts from Greek olive cultivars. J Am Oil Chem Soc 87: 369-376.
22. Lee OH, Lee BY,. 2010. Antioxidant and antimicrobial activities of individual and combined phenolics in Olea europaea leaf extract. Bioresour Technol 101: 3751-3754.
23. Marone M, Mozzetti S, Ritis DD, Pierelli L, Scambia G,. 2001. Semiquantitative RT-PCR analysis to assess the expression levels of multiple transcripts from the same sample. Biol Proced Online 3: 19-25.
24. Meng G, Wu N, Zhang C, et al,. 2008. Analgesic activity of ZC88, a novel N-type voltage-dependent calcium channel blocker, and its modulation of morphine analgesia, tolerance and dependence. Eur J Pharmacol 586: 130-138.
25. 2+ channel antagonists on morphine analgesia, tolerance and dependence, and on blood pressure in the rat. Eur J Pharmacol 352: 189-197.
26. Mohagheghi F, Bigdeli MR, Rasoulian B, Hashemi P, Pour MR,. 2011. The neuroprotective effect of olive leaf extract is related to improved blood-brain barrier permeability and brain edema in rat with experimental focal cerebral ischemia. Phytomedicine 18: 170-175.
27. 2+ channel and adenylyl cyclase modulation by cloned mu-opioid receptors in GH3 cells. Mol Pharmacol 47: 1041-1049.
28. Qiusheng Z, Yuntao Z, Rongliang Z, Dean G, Changling L,. 2005. Effects of verbascoside and luteolin on oxidative damage in brain of heroin treated mice. Pharmazie 60: 539-543.
29. Ramkumar V, El-Flakani EE,. 1988. Prolonged morphine treatment increase rat brain dihydropyridine binding sites: possible involvement in development of morphine dependence. Eur J Pharmacol 146: 73-83.
30. Ray SB, Mishra P, Verma D, Gupta A, Wadhwa S,. 2008. Nimodipine is more effective than nifedipine in attenuating morphine tolerance on chronic co-administration in the rat tail-flick test. Indian J Exp Biol 46: 219-228.
31. Salvemini D., 2009. Peroxynitrite and opiate antinociceptive tolerance: a painful reality. Arch Biochem Biophys 484: 238-244.
32. Santilan R, Maestre JM, Hurle MA, Florez J,. 1994. Enhancement of opiate analgesia by nimodipine in cancer patients chronically treated with morphine: a preliminary report. Pain 58: 129-132.
33. +2 channel antagonistic effects. J Ethnopharmacol 120: 233-240.
34. Shibasaki M, Katsura M, Kurokawa K, Torigoe F, Ohkuma S,. 2007. Regional differences of L-type high voltage-gated calcium channel subunit expression in the mouse brain after chronic morphine treatment. J Pharmacol Sci 105: 177-183.
35. Smith FL, Dombrowski SD, Deway LW,. 1999. Involvement of intracellular calcium in morphine tolerance in mice. Pharmacol Biochem Behav 62: 381-388.
36. Verma D, Gupta YK, Parashar A, Ray SB,. 2009. Differential expression of L- and N-type voltage-sensitive calcium channels in the spinal cord of morphine + nimodipine treated rats. Brain Res 1249: 128-134.
37. 2+ in synaptosomes. Life Sci 48: 1853-1861.
38. Xiao GS, Zhou JJ, Wang GY, Cao CM, Li GR, Wong TM,. 2005. In vitro electrophysiologic effects of morphine in rabbit ventricular myocytes. Anesthesiology 103: 280-286.
39. Zimmermann M., 1983. Ethical guidelines for investigations of experimental pain in conscious animals. Pain 16: 109-110.