Differential expression of L- and N-type voltage-sensitive calcium channels in the spinal cord of morphine + nimodipine treated rats

Brain Research

Volumn 1249, Issue , 2009, Pages 128-134

  Verma, Dilip ^a   Gupta, Y K ^a   Parashar, Akhil ^a   Ray, Subrata Basu ^a  

^a ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

Ca2+ channel; Dorsal horn; Immunohistochemistry; Morphine tolerance; Pain

Indexed keywords

CALCIUM CHANNEL L TYPE; CALCIUM CHANNEL N TYPE; MORPHINE; NIMODIPINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN REGION; CONTROLLED STUDY; DRUG TOLERANCE; IMMUNOHISTOCHEMISTRY; MALE; NONHUMAN; PAIN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SPINAL CORD;

ANALYSIS OF VARIANCE; ANIMALS; CALCIUM CHANNELS, L-TYPE; CALCIUM CHANNELS, N-TYPE; DRUG TOLERANCE; IMMUNOHISTOCHEMISTRY; MALE; MORPHINE; NIMODIPINE; POSTERIOR HORN CELLS; RATS; RATS, WISTAR; SPINAL CORD;

ANIMALIA; RATTUS;

EID: 58149117554     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2008.10.038     Document Type: Article

References (39)

1. Abbadie C., Lombard M.C., Besson J.M., Trafton J.M., and Basbaum A.I. Mu and delta opioid receptor like immunoreactivity in the cervical spinal cord of the rat after dorsal rhizotomy or neonatal capsaicin: an analysis of pre- and postsynaptic receptor distributions. Brain Res. 930 (2002) 150-162
2. Bernstein M.A., and Welch S.P. Alterations in L-type calcium channels in the brain and spinal cord of acutely treated and morphine-tolerant mice. Brain Res. 696 (1995) 83-88
3. Brand-Schieber E., and Werner P. Calcium channel blockers ameliorate disease in a mouse model of multiple sclerosis. Exp. Neurol. 189 (2004) 5-9
4. 2+ channels and axonic injury in rat CNS white matter. J. Neurophysiol. 85 (2001) 900-911
5. Catterall W.A., Perez-Reyes E., Snutch T.P., and Striessnig J. International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels. Pharmacol. Rev. 57 (2005) 411-425
6. 2+ channels in the rat spinal cord following chronic constrictive nerve injury. Exp. Brain Res. 147 (2002) 456-463
7. 2+ channels in rat cortical astrocytes. Glia 45 (2004) 354-363
8. Diaz A., Florez J., Pazos A., and Hurle M.A. Opioid tolerance and supersensitivity induce regional changes in the autoradiographic density of dihydropyridine-sensitive calcium channels in the rat central nervous system. Pain 86 (2000) 227-235
9. Dierssen M., Florez J., and Hurle M.A. Calcium channel modulation by dihydropyridines modifies sufentanil-induced antinociception in acute and tolerant conditions. Naunyn Schmiedeberg's Arch. Pharmacol. 342 (1990) 559-565
10. Dobremez E., Bouali-Benazzouz R., Fossat P., Monteils L., Dulluc J., Nagy F., and Landry M. Distribution and regulation of L-type calcium channels in deep dorsal horn neurons after sciatic nerve injury in rats. Eur. J. Neurosci. 21 (2005) 3321-3333
11. Dogrul A., Bilsky E.J., Ossipov M.H., Lai J., and Porreca F. Spinal L-type calcium channel blockade abolishes opioid-induced sensory hypersensitivity and antinociceptive tolerance. Anesth. Analg. 101 (2005) 1730-1735
12. Gupta H., Verma D., Ahuja R.K., Srivastava D.N., Wadhwa S., and Ray S.B. Intrathecal co-administration of morphine and nimodipine produces higher antinociceptive effect by synergistic interaction as evident by injecting different doses of each drug in rats. Eur. J. Pharmacol. 561 (2007) 46-53
13. Hagiwara S., and Byerly L. Calcium channel. Annu. Rev. Neurosci. 4 (1981) 69-125
14. Haller V.L., Bernstein M.A., and Welch S.P. Chronic morphine treatment decreases the Ca(v)1.3 subunit of the L-type calcium channel. Eur J. Pharmacol. 578 (2008) 101-107
15. Hell J.W., Westenbroek R.E., Warner C., Ahlijanian M.K., Prystay W., Gilbert M.M., Snutch T.P., and Catterall W.A. Identification and differential subcellular localization of the neuronal class C and class D L-type calcium channel alpha 1 subunit. J. Cell Biol. 123 (1993) 949-962
16. Johnson E.E., Chieng B., Napier I., and Connor M. Decreased μ-opioid receptor signaling and a reduction in calcium current density in sensory neurons from chronically morphine-treated mice. Br. J. Pharmacol. 148 (2006) 947-955
17. Katsura M., Torigoe F., Hayashida S., Honda T., Tsujimura A., and Ohkuma S. Ethanol physical dependence is accompanied by up-regulated expression of L-type high voltage-gated calcium channel α1 subunits in mouse brain. Brain Res. 1039 (2005) 211-215
18. Katsura M., Shibasaki M., Kurokawa K., Tsujimura A., and Ohkuma S. Up-regulation of L-type high voltage-gated calcium channel subunits by sustained exposure to 1,4- and 1,5-benzodiazepines in cerebrocortical neurons. J. Neurochem. 103 (2007) 2518-2528
19. Law P.Y., Wong Y.H., and Loh H.H. Molecular mechanisms and regulation of opioid receptor signaling. Annu. Rev. Pharmacol. Toxicol. 40 (2000) 389-430
20. Matthews E.A., and Dickenson A.H. Effects of spinally delivered N- and P-type voltage-dependent calcium channel antagonists on dorsal horn neuronal responses in a rat model of neuropathy. Pain 92 (2001) 235-246
21. 2+ channel antagonists on morphine analgesia, tolerance and dependence, and on blood pressure in the rat. Eur. J. Pharmacol. 352 (1998) 189-197
22. 2+ channels at the primary afferent neurons in mice. Eur. J. Pharmacol. 419 (2001) 175-181
23. 1 subunits in the dorsal horn of spinal cord in mice. Brain Res. 1024 (2004) 122-129
24. 2+ channel alpha 1C (Cav1.2) to synaptic and extrasynaptic compartments in hippocampal neurons. Eur. J. Neurosci. 19 (2004) 2109-2122
25. Ray S.B., and Wadhwa S. The enigma of morphine tolerance: recent insights. J. Biosci. 26 (2001) 555-559
26. Ray S.B., Gupta H., and Gupta Y.K. Up-regulation of μ-opioid receptors in the spinal cord of morphine-tolerant rats. J. Biosci. 29 (2004) 51-56
27. Ray S.B., Mishra P., Verma D., Gupta A., and Wadhwa S. Nimodipine is more effective than nifedipine in attenuating morphine tolerance on chronic co-administration in the rat tail-flick test. Indian J. Exp. Biol. 46 (2008) 219-228
28. Reid C.A., Bekkers J.M., and Clements J.D. Presynaptic calcium channels: a functional patchwork. Trends Neurosci. 26 (2003) 683-687
29. Ruskin K.I., and Moises H.C. mu-Opioid receptor activation reduces multiple components of high-threshold calcium current in rat sensory neurons. J. Neurosci. 15 (1995) 4315-4327
30. Shibasaki M., Katsura M., Kurokawa K., Torigoe F., and Ohkuma S. Regional differences of L-type high voltage-gated calcium channel subunit expression in the mouse brain after chronic morphine treatment. J. Pharmacol Sci. 105 (2007) 177-183
31. Smith F.L., Dombrowski D.S., and Dewey W.L. Involvement of intracellular calcium in morphine tolerance in mice. Pharmacol. Biochem. Behav. 62 (1999) 381-388
32. Trimmer J.S., and Rhodes K.J. Localization of voltage-gated ion channels in mammalian brain. Annu. Rev. Physiol. 66 (2004) 477-519
33. Wang Y.X., Gao D., Pettus M., Phillips C., and Bowersox S.S. Interactions of intrathecally administered ziconotide, a selective blocker of neuronal N-type voltage-sensitive calcium channels, with morphine on nociception in rats. Pain 84 (2000) 271-281
34. Welch S.P., and Olson K.G. Opiate-tolerance-induced modulation of free intracellular calcium in synaptosomes. Life Sci. 48 (1991) 1853-1861
35. Westenbroek R.E., Hell J.W., Warner C., Dubel S.J., Snutch T.P., and Catterall W. Biochemical properties and subcellular distribution of an N-type calcium channel α1 subunit. Neuron 6 (1992) 1099-1115
36. 2+ channels. J. Neurosci. 15 (1995) 6403-6418
37. 2+ channel subtypes on rat spinal motor neurons, interneurons, and nerve terminals. J. Neurosci. 18 (1998) 6319-6330
38. 2+ channel currents to a mu opioid in isolectin B4-positive and -negative dorsal root ganglion neurons. J. Pharmacol. Exp. Ther. 311 (2004) 939-947
39. Yokoyama K., Kurihara T., Makita K., and Tanabe T. Plastic change of N-type Ca channel expression after preconditioning is responsible for prostaglandin E2-induced long-lasting allodynia. Anesthesiology 99 (2003) 1364-1370