Blockade of nitric oxide overproduction and oxidative stress by Nigella sativa oil attenuates morphine-induced tolerance and dependence in mice

Neurochemical Research

Volumn 35, Issue 10, 2010, Pages 1557-1565

  Abdel Zaher, Ahmed O ^a   Abdel Rahman, Mahran S ^a   Elwasei, Fahmy M ^a  

^a Assiut University Faculty of Medicine   (Egypt)

Author keywords

Dependence; Morphine; Nigella sativa oil; Nitric oxide; Oxidative stress; Tolerance

Indexed keywords

7 NITROINDAZOLE; ACETYLCYSTEINE; AMINOGUANIDINE; BLACK CUMIN EXTRACT; DIZOCILPINE; DIZOCILPINE MALEATE; ESSENTIAL OIL; GLUTAMIC ACID; GLUTATHIONE; GLUTATHIONE PEROXIDASE; MALONALDEHYDE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; PLANT EXTRACT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLACK CUMIN; BRAIN LEVEL; CONTROLLED STUDY; DRUG EFFECT; DRUG POTENTIATION; ENZYME ACTIVITY; HOT PLATE TEST; MALE; MORPHINE ADDICTION; MORPHINE TOLERANCE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; REPEATED DRUG DOSE; WITHDRAWAL SYNDROME;

ANALGESICS, OPIOID; ANIMALS; BRAIN; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG TOLERANCE; MALE; MICE; MORPHINE; MORPHINE DEPENDENCE; NIGELLA SATIVA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; OXIDATIVE STRESS; PLANT OILS; SUBSTANCE WITHDRAWAL SYNDROME;

MUS; NIGELLA SATIVA;

EID: 77957606509     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11064-010-0215-2     Document Type: Article

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